Sentences with phrase «in human airway»

Olsen CE, Liguori AE, Zong Y, Lantz RC, Burgess JL, Boitano S. Arsenic upregulates MMP - 9 and inhibits wound repair in human airway epithelial cells.

A multi-institution research team that includes Children's National Health System attempted to characterize gender - based epigenomic signatures in the human airway early in children's lives with a special attention to defining DNA methylation patterns of the X chromosome.

According to Earl Brown, professor of medicine at the University of Ottawa, the more limited ability of the avian flu virus to infect cells in the human airway thus also appears to be associated with infection of the deep areas of the lung where oxygen and carbon dioxide are exchanged.

In both human airway cells and mouse nasal cells, the researchers observed corrections in the targeted genes.

«In our human airway epithelial model system, one of the drugs destabilizes and deactivates the protein that the other drug tries to correct,» said Martina Gentzsch, PhD, an assistant professor of cell biology and physiology and senior author of the UNC Science Translational Medicine paper.

The new coronavirus latches onto a protein called dipeptidyl peptidase 4, or DPP4, which decorates the surface of many cells, including some in human airways and kidneys, Bart Haagmans of Erasmus Medical Center in Rotterdam, the Netherlands, and colleagues report in the March 14 Nature.

Not exact matches

Scientists at the Johns Hopkins Kimmel Cancer Center say they have preliminary evidence in laboratory - grown, human airway cells that a condensed form of cigarette smoke triggers so - called «epigenetic» changes in the cells consistent with the earliest steps toward lung cancer development.

To create the effect of tobacco smoke on cells, Vaz, Baylin and their colleagues began their studies with human bronchial cells, which line the airways of the lungs, and grew them in a laboratory.

The unaltered hemagglutinin is akin to a key that unlocks a so - called receptor molecule in cells lining the upper airways of humans and other mammals.

In earlier work, Stevens and his co-workers altered the equivalent amino acids in H5N1 that Tumpey's group did for 1918 flu, but the virus failed to acquire a preference for the human upper airway receptoIn earlier work, Stevens and his co-workers altered the equivalent amino acids in H5N1 that Tumpey's group did for 1918 flu, but the virus failed to acquire a preference for the human upper airway receptoin H5N1 that Tumpey's group did for 1918 flu, but the virus failed to acquire a preference for the human upper airway receptor.

Now, scientists from the Perelman School of Medicine at the University of Pennsylvania reveal that the release of AMPs is partially controlled by bitter taste receptors in the upper airway on a cell previously identified in animals and only recently in humans known as solitary chemosensory cells (SCCs).

Human nasal epithelial cells, cultured on a microchip, react to air pollutants just like they would in the upper airway.

«Since the virus doesn't have attachment factors that can work in the upper airway, it's very rare for it to go human to human, and then it almost always stops and doesn't get to a third person,» Schaffner notes.

«We compared the ability of RSV and parainfluenza virus (PIV3)-- another common virus in children that causes much less severe airway disease — to infect and cause inflammatory responses in a cell culture model of human epithelial cells, which compose the lining of the lung airway.

When Liesman infected human airway cells in the lab with this re-engineered virus, she saw infected cells ball up and puff out of the airway epithelium.

Their test includes three types of human cells that are typically in a person's airway.

If this type of therapy proves safe in humans, a syringe full of oxygen microbubbles could help avert brain damage and death for the victims of cardiac arrest, asthma attacks, strokes, and injuries to the lungs, airway, or face.

Asthma is a disease of the human respiratory system in which the airways narrow, often in response to a «trigger» such as exposure to an allergen, cold air, exercise, or emotional stress.

Human flu strains can infect both kinds of cells, but avian flu strains can bind to and infect only the ciliated kind, which are similar to cells in the airway and the gut of birds.

Microscopic images show that RMC - 1 prevented FOXM1 from entering the nucleus in cultured human airway epithelial cells and in mouse allergen - sensitized respiratory airways.

A number of bacterial and viral infections can gain a foothold in the human body through adsorption via the intestines and airways, such as Salmonella and the flu.

The research team then tested RMC - 1 in cultured human airway epithelial cells and mouse models of asthma (via injection into the animals» peritoneal cavities).

«This is a whole new way of looking at immune surveillance in the epithelium of the human gut and airway,» said Lo, a distinguished professor in the medical school's Division of Biomedical Sciences.

Hypertonic Saline Primes Activation of the p53 — p21 Signaling Axis in Human Small Airway Epithelial Cells That Prevents Inflammation Induced by Pro-inflammatory Cytokines.

The public disclosure of this expanded collaboration coincides with the publication in the peer reviewed journal Nature Methods of data showing new capabilities of the Lung - Chip technology to achieve accurate modeling of the human lung small airways.

Building on that project, the researchers have now designed a machine that smokes cigarettes in a very human - like manner, and hooked it up to organs - on - chips lined by human lung small airway cells so the smoke interacts with these cells in a realistic way.

This micro-engineered Airway Lung - Chip recapitulates key features of viral - induced human asthma exacerbation and provides unique opportunities to explore the complex mechanisms underlying asthma exacerbation in a human - relevant model.

Monell researcher and University of Pennsylvania medical student Jennifer Douglas will discuss new frontiers in taste biology, with a focus on taste receptors located throughout the human body (including the stomach, intestines, pancreas, testes, and airways).

The bill, expected to come up for a vote in the Senate after Thanksgiving, also would require the U.S. Centers for Disease Control and Prevention to conduct a five - year study on the human health effects of per - and polyfluoroalkyl substances — classes that include the compounds in Airway Heights» groundwater.

Enhanced Expression of Myristoylated Alanine — Rich C Kinase Substrate (MARCKS) in Airway Epithelium of an Animal Model of Allergic Airway Inflammation and Human Patients with COPD

Additionally, we clarified the role of iNKT cells in human asthma by carefully enumerating cell numbers in airway samples from asthma and COPD patients.

Once produced, NO is freely diffusible and enters target cells and into the airway and can be detected in exhaled breath of all humans.

IMAGE: Human airways already demonstrate gender - based differences in DNA methylation signatures at birth, providing an early hint of which infants may be predisposed to develop respiratory disorders like asthma later in...

In this study, published in Stem Cell Reports, the researchers used both murine and human pluripotent stem cell lines with airway secretory lineage reporters, which enables their tracking, purification and profilinIn this study, published in Stem Cell Reports, the researchers used both murine and human pluripotent stem cell lines with airway secretory lineage reporters, which enables their tracking, purification and profilinin Stem Cell Reports, the researchers used both murine and human pluripotent stem cell lines with airway secretory lineage reporters, which enables their tracking, purification and profiling.

WASHINGTON - Human airways already demonstrate gender - based differences in DNA methylation signatures at birth, providing an early hint of which infants may be predisposed to develop respiratory disorders like asthma later in life, a research team reports in a paper published online April 3, 2018, in Scientific Reports.

Similar to asthma in humans, these airways can become inflamed and make it difficult for your cat to breathe.

For example, in humans we know that while actual symptoms of asthma occur in episodes, the airways of the lung are diseased all the time.

Feline asthma is similar to human asthma, in that it is a chronic inflammation of the airways inside the lungs.

In humans, and in particular asthmatics, increases in specific airway resistance or decreases in forced expiratory volume or forced expiratory flow are the primary response following acute exposure.In humans, and in particular asthmatics, increases in specific airway resistance or decreases in forced expiratory volume or forced expiratory flow are the primary response following acute exposure.in particular asthmatics, increases in specific airway resistance or decreases in forced expiratory volume or forced expiratory flow are the primary response following acute exposure.in specific airway resistance or decreases in forced expiratory volume or forced expiratory flow are the primary response following acute exposure.in forced expiratory volume or forced expiratory flow are the primary response following acute exposure...