Sentences with phrase «in human diseases such»

Our computational biology research programme focuses on gene expression regulation and the mechanisms by which it can be disrupted in human diseases such as cancer.

Not exact matches

What it does: This bacteria is most notorious for causing severe illnesses such as tuberculosis, leprosy, and Hansen's disease, though most species of mycobacteria in nature are benign in humans, unless in cases of those who have weakened immune systems.

InvivoSciences will continue to contribute to the improvement of human health by establishing a new paradigm for discovering drugs that focus on diseases with limited treatment options such as cardiac fibrosis, scleroderma, and lupus in a time - effective manner while remaining safe and cost effective.»

research; since most of the reports have concentrated on justifying the creation of cloned human embryos for research into and treatment of neurodegenerative diseases such as Parkinson's, «stem - cells» has become synonymous with «embryonic stem - cells» in the public imagination.

When we think of all that has come from him in the impulse toward human freedom and dignity — the challenge of ignorance and the attempt to remedy it, the concern for and conquest of disease, the sensitivity to the needs and plight of the weak, destitute, helpless, and those in every kind of suffering, the stabilizing of the inner lives of millions of his followers around the world, and the fostering of a prophetic attack on such giant social evils as prejudice, injustice, and war — when we consider the things that have stemmed from this «penniless teacher of Nazareth,» we are dull indeed if the wonder of it does not sweep over our souls.

Indeed in agriculture and in human and animal health, diseases are now forestalled wherever possible, by such methods as the application of trace elements to the soil, sterilization, a balanced diet and immunization.

With the advances in knowledge that are almost certain to be gained from the Human Genome Initiative — or, if its critics should win the day and it lose support, from more piecemeal genetic - research — we will know more and - more about genetic factors causally related to health and disease and to other important aspects of life, such as intelligence and emotional states.

Such an attitude is ultimately in conflict with itself; for the urge to cure disease presupposes openness to the human dignity of sufferers and concern for them.

Out of the Earth ~ Natural Raw Diet for Dogs Many of the commercial dog food companies would have us believe that they actually use human grade meat in the production of their food, when in fact the sources of this «meat» are not even fit for animal consumption.In some areas of North America this list can also include euthanized companion animals from clinics and shelters, roadkill, zoo animals, livestock which die from disease or disability.The «meat» is purchased from a rendering plant which also receives material from slaughterhouses such as hair, feathers, hooves and any part of the mammal which is condemned for human consumtion.

Many of the commercial dog food companies would have us believe that they actually use human grade meat in the production of their food, when in fact the sources of this «meat» are not even fit for animal consumption.In some areas of North America this list can also include euthanized companion animals from clinics and shelters, roadkill, zoo animals, livestock which die from disease or disability.The «meat» is purchased from a rendering plant which also receives material from slaughterhouses such as hair, feathers, hooves and any part of the mammal which is condemned for human consumtion.

According to the University of Maryland Medical Center polyunsaturated fatty acids (PUFAs)-- also known as omega - 3 fatty acids — play a crucial role in human brain function, as well as normal growth and development, with research showing that they can also reduce inflammation in addition to helping lower the risk of chronic diseases such as heart disease, cancer, and arthritis.

Such standards help eliminate product contamination by any number of microorganisms known to cause dangerous infection and disease in humans.

The U.S. Centers for Disease Control and Prevention (CDC) says human exposure to BPA has dropped significantly in recent years, but some health and environmental groups believe more needs to be done to get BPA out of consumer products because a wide range of products — such as food storage containers, plastic tableware, and food packaging — are still manufactured with BPA.

In Canada, vaccines prevent illnesses such as diphtheria, tetanus, pertussis (whooping cough), polio, Haemophilus influenzae type B (Hib), rotavirus, hepatitis B, measles, mumps, rubella, chickenpox, pneumococcal and meningococcal diseases, and human papillomavirus virus (HPV).

These and other food allergens implicated in atopic disease, such as egg and peanut, can be detected in human breast milk 4 hours after maternal intake and remain in the milk for several days (20).

Additional human studies are needed to explore how individual differences in maternal breast milk composition could predispose to intestinal inflammatory conditions, such as allergic disease.

Risks for the baby include exposure to infectious diseases, including HIV, to chemical contaminants, such as some illegal drugs, and to a limited number of prescription drugs that might be in the human milk, if the donor has not been adequately screened.

Studies have shown that a protein in human milk aids in brain development, and breast - fed babies are less likely to get gastrointestinal infections and diarrhea, respiratory and ear infections or more serious diseases such as pneumonia, and there is a lower risk of Sudden Infant Death Syndrome.

As a human being: As a human being living in Africa, I am more prone to die through preventable diseases such as cholera and malaria; it is more probable that I will experience wars and conflicts; I am more likely to live under one dollar a day and for either myself or my children to suffer from malnutrition.

And you may end up being born in utter poverty that may prevent you from being happy, or you may start off being wealthy but then you may suffer calamities like disease and natural disasters, so assuming you're risk averse (as humans tend to be in most circumstances), you'd want the government to have a safety net to shelter you from such risks.

The charity said this was «particularly concerning» as most of these experiments studied human diseases which do not exist in non-human primates, such as Parkinson's Disease, and this they suggested «significantly challenges» the validity of the tests.

Of the thousands of ancestral variants reintroduced into modern humans, only 41 have been linked in genetic studies to diseases, such as skin conditions and neurological and psychiatric disorders, he said.

The genome - editing technique earned top honors, in part because of achievements such as «the creation of a long - sought «gene drive» that could eliminate pests or the diseases they carry, and the first deliberate editing of the DNA of human embryos.»

Since the first human brain organoids were created from stem cells in 2013, scientists have gotten them to form structures like those in the brains of fetuses, to sprout dozens of different kinds of brain cells, and to develop abnormalities like those causing neurological diseases such as Timothy syndrome.

One - third of yeast genes have counterparts in the human genome, many of which are associated with diseases, such as cancer.

The stocks are helping the development of new countermeasures such as drugs, vaccines and diagnostics in case smallpox should reappear, and may also allow researchers to explore the impact of smallpox on the human immune system, providing insights into other diseases such as AIDS.

Human embryonic stem cells are at last being tested in common, potentially fatal diseases such as heart failure and diabetes

The behavioral tests used here modeled one dimension of the disease — an inability to experience pleasure from normal activities — but not others, such as stress and anxiety, and probably tap into different brain mechanisms in mice than in humans, he says.

In humans, prion diseases can cause a variety of rapidly progressive neurological symptoms, such as difficulty walking and speaking, and dementia.

The results, published online in the journal Brain, Behavior and Immunity, strengthen the case that transgenic Huntington's disease monkeys could be used to evaluate emerging treatments (such as this) before launching human clinical trials.

The findings, appearing online Feb. 19, 2015, in Current Biology, may lend insight into not only what makes the human brain special but also why people get some diseases, such as autism and Alzheimer's disease, whereas chimpanzees don't.

In the United States, some of the most alarming outbreaks are occurring in the suburbs, where rising temperatures may help explain the spike in such tick - borne illnesses as babesiosis; hga (human granulocytic anaplasmosis), a potentially lethal flulike infection; and Lyme disease, the most common vector - borne disease in this countrIn the United States, some of the most alarming outbreaks are occurring in the suburbs, where rising temperatures may help explain the spike in such tick - borne illnesses as babesiosis; hga (human granulocytic anaplasmosis), a potentially lethal flulike infection; and Lyme disease, the most common vector - borne disease in this countrin the suburbs, where rising temperatures may help explain the spike in such tick - borne illnesses as babesiosis; hga (human granulocytic anaplasmosis), a potentially lethal flulike infection; and Lyme disease, the most common vector - borne disease in this countrin such tick - borne illnesses as babesiosis; hga (human granulocytic anaplasmosis), a potentially lethal flulike infection; and Lyme disease, the most common vector - borne disease in this countrin this country.

This is advantageous, since dogs provide new models to investigate the disease mechanisms and to plan new therapies such as gene therapy, successfully applied to blindness in dogs and human previously,» explains Lohi.

An inflammatory protein that triggers a pregnant mouse's immune response to an infection or other disease appears to cause brain injury in her fetus, but not the premature birth that was long believed to be linked with such neurologic damage in both rodents and humans, new Johns Hopkins - led research suggests.

Chotiwan et al. describe a loop - mediated amplification (LAMP) assay that detects Zika virus RNA in human biofluids such as serum and semen as well as in mosquitoes, the insect vector that transmits the disease.

«It has profound implications for our understanding of human development and physiology, and gives us a remarkable wealth of resources to examine how disturbances of this system might result in diseases such as cancer.»

Unexplained cases of spontaneous reversions also appear in human genetic diseases, although the natural frequency of such events is unclear.

«This paper represents an exciting advance in a field that has become increasingly important with the discovery that defects in RNA - binding proteins contribute to human diseases such as metabolic disorders, cancer and neurodegeneration,» Lipshitz said.

Hunting and deforestation have already brought chimpanzees to the brink of extinction, but «diseases such as anthrax, Ebola, or introduced human respiratory viruses may serve as the final nail in their coffin,» says disease ecologist Tom Gillespie of Emory University in Atlanta.

These techniques include: human tissue created by reprogramming cells from people with the relevant disease (dubbed «patient in a dish»); «body on a chip» devices, where human tissue samples on a silicon chip are linked by a circulating blood substitute; many computer modelling approaches, such as virtual organs, virtual patients and virtual clinical trials; and microdosing studies, where tiny doses of drugs given to volunteers allow scientists to study their metabolism in humans, safely and with unsurpassed accuracy.

The first group includes such diseases as type 2 diabetes and cardiovascular disease, whose incidence is linked to recent changes in human environment and lifestyle.

The paramyxovirus family includes virus that cause important diseases in humans and animals, such as measles virus, mumps virus, human parainfluenza virus, human respiratory syncytial virus, canine distemper virus, Newcastle disease virus, and Nipah virus.

The study was done with rodent malaria, but the researchers, at Pennsylvania State University in University Park, expect the pattern to apply to human malaria and possibly to other mosquito - borne diseases such as dengue fever and West Nile virus.

To maintain its foothold in large - scale, world - class research, Japan has launched its own Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain / MINDS) project, in line with the increasing interest in brain - mapping projects around the world, such as the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative project in the United States and the Human Brain Project (HBP) in Europe.

In humans, too much fructose puts the liver at risk for conditions such as fatty liver disease, and raises the overall risk of obesity and type 2 diabetes (SN: 10/5/13, p. 18).

Unseen by the human eye, plants interact with many species of fungi and other microbes in the surrounding environment, and these exchanges can impact the plant's health and tolerance to stressors such as drought or disease, as well as the global carbon cycle.

Poinar suggested in the journal American Entomologist that the origins of this deadly disease, which today can infect animals ranging from humans and other mammals to birds and reptiles, may have begun in an insect such as the biting midge more than 100 million years ago.

The researchers caution, however, that it's not yet clear how closely the toxin - induced neural damage in rats mimics the state of diseased neurons in Parkinson's, especially because the mechanism that leads to such damage in humans remains unknown.

They found that although the protein stayed soluble for a week or two, it eventually polymerized into long fibers resembling those in so - called prion diseases — brain diseases such as scrapie in sheep, «mad cow disease» in cattle, and Creutzfeldt - Jakob disease in humans.

Changes in the composition of the gut microbiota are seen in many human diseases such IBD, a chronic, lifelong inflammatory disorder that includes Crohn's disease and ulcerative colitis.