Sentences with phrase «in human keratinocytes»

Annexin A2 and S100A10 regulate human papillomavirus type 16 entry and intracellular trafficking in human keratinocytes.

Induction of GITRL expression in human keratinocytes by Th2 cytokines and TNF - α: implications for atopic dermatitis.

AV119, a Natural Sugar from Avocado gratissima, Modulates the LPS - Induced Proinflammatory Response in Human Keratinocytes.

Not exact matches

A comparison of epidermal equivalents generated from iPSC, hESC and primary human keratinocytes (skin cells) from skin biopsies showed no significant difference in their structural or functional properties compared with the outermost layer of normal human skin.

«We culture typical skin cell of the epidermis, such as human keratinocytes, in our dishes to form an artificial epidermis with all of its natural layers,» explained Sibylle Thude, the biologist who led the investigation into the accreditation.

Wei Long Ng explained: «The two - step bioprinting strategy involves the fabrication of hierarchical porous collagen - based structures (that closely resembles the skin's dermal region), and deposition of epidermal cells such as keratinocytes and melanocytes at pre-defined positions on top of the biomimetic dermal skin constructs, to create 3D in - vitro pigmented human skin constructs.

In humans, iRhoms have been implicated in EGFR - mediated keratinocyte proliferation and cancer growth, but the molecular mechanisms underlying these biological functions have not been well defined.&raquIn humans, iRhoms have been implicated in EGFR - mediated keratinocyte proliferation and cancer growth, but the molecular mechanisms underlying these biological functions have not been well defined.&raquin EGFR - mediated keratinocyte proliferation and cancer growth, but the molecular mechanisms underlying these biological functions have not been well defined.»

Papillomaviruses are a diverse group of DNA - based viruses that infect the skin and mucous membranes of humans and a variety of animals (replicating exclusively in keratinocytes).

In human skin, keratinocytes, the cells found in the outer layer of our skin known as the epidermis, soak up our naturally occurring melanosomeIn human skin, keratinocytes, the cells found in the outer layer of our skin known as the epidermis, soak up our naturally occurring melanosomein the outer layer of our skin known as the epidermis, soak up our naturally occurring melanosomes.

Gianneschi and his team found that the synthetic melanin nanoparticles in their experiments were not only absorbed and distributed normally by the keratinocytes in the epidermis, but they also protected human skin cells from UV radiation damage.

For the expansion and differentiation of human keratinocyte stem cells for permanent skin restoration in victims of extensive burns.

Ng explains, «The two - step bioprinting strategy involves the fabrication of hierarchical porous collagen - based structures (that closely resembles the skin's dermal region), and deposition of epidermal cells such as keratinocytes and melanocytes at pre-defined positions on top of the biomimetic dermal skin constructs, to create 3D in - vitro pigmented human skin constructs.

Functional and phenotypic characterization of human keratinocytes expanded in microcarrier culture.

In fact, they repeatedly generated iPS cells from the tiny number of keratinocytes attached to a single hair plucked from a human scalp.

The researchers then successfully prodded what they call keratinocyte - derived iPS cells or KiPS cells to distinguish them from fibroblast - derived iPS cells into becoming all the cell types in the human body, including heart muscle cells and dopamine - producing neurons, which are affected by Parkinson's disease.

For the first set of experiments, first author Trond Aasen, Ph.D., a postdoctoral researcher at the Center of Regenerative Medicine in Barcelona, used viral vectors to slip the genes for the master regulators Oct4, Sox2, as well as Klf4 and c - Myc into keratinocytes cultured from human skin explants.

In a study published in Molecular & Cellular Proteomics, researchers at the University of Freiburg led by Jorn Dengjel performed a global transcriptome and proteome profiling comparing primary DEB keratinocytes to normal human keratinocyteIn a study published in Molecular & Cellular Proteomics, researchers at the University of Freiburg led by Jorn Dengjel performed a global transcriptome and proteome profiling comparing primary DEB keratinocytes to normal human keratinocytein Molecular & Cellular Proteomics, researchers at the University of Freiburg led by Jorn Dengjel performed a global transcriptome and proteome profiling comparing primary DEB keratinocytes to normal human keratinocytes.

The research, described in the journal Stem Cells under the title «Reprogramming Postnatal Human Epidermal Keratinocytes Toward Functional Neural Crest Fates,» was supported by grants from the National Institutes of Health.

Pioneering work by Barrandon and Green more than 20 years ago (2) showed that when primary human keratinocytes were put in culture, their abilities to establish a clone were related to the heterogeneity in cell size — only cells ≤ 11 μm in diameter could form a clone whereas cells ≥ 12 μm were irreversibly committed to terminal differentiation.

Parsa R, Yang A, McKeon F, Green H. Association of p63 with proliferative potential in normal and neoplastic human keratinocytes.