Sentences with phrase «in human microbiota»

Associate Professor D'Amato said: «Primarily a proof - of - concept investigation, our pilot study reinforces the idea that large - scale analyses should be undertaken to unravel how variation in the entire human genome relates to variation in the human microbiota.»

Commensal Koch's postulates: establishing causation in human microbiota research — Anne Neville — Current Opinion in Microbiology

Not exact matches

How do the microbes within cheese interact with the natural microbiota of the human gut and can cheese be used to assist in maintaining a healthy gut microbiota?

The human microbiome is the composite of genes of the microorganisms (microbiota) living in and on the human body that influence the health and development of the host (1).

Her main research areas are Perinatal and human milk microbiota and Characterization of probiotic bacteria and study of their use in bacterial dysbiosis.

The age - related successional mechanisms involved in the differentiation of the human microbiota across body habitats are only beginning to be understood (6), and defining the pioneer colonizers is a first step toward elucidating the initial stages of microbiota development.

In collaboration with Synchrotron Oxford, the University of East Anglia and the University of California, the researchers, using a commonly - found member of human gut microbiota called Ruminococcus gnavus as a model organism identified carbohydrate binding modules with the ability to bind to mucus.

Over 100 different oligosaccharides have been identified in the human colon, and recent research has shown that variations in the oligosaccharides within the mucus are associated with variations in the composition of the gut microbiota.

«Alterations in the gut microbiota are associated with obesity and the metabolic syndrome in both humans and rodents,» Shulman noted.

The researchers found that changes in the amount of protein and carbohydrates in the diet had a similar effect on the microbiota of dogs and humans, independent of the dog's breed or sex.

Dr Luis Pedro Coelho, commented: «These findings suggest that dogs could be a better model for nutrition studies than pigs or mice and we could potentially use data from dogs to study the impact of diet on gut microbiota in humans, and humans could be a good model to study the nutrition of dogs.

As noted by Dr. Vicki Ellingrod — the Chair of this session, «Current state - of - the - art research in both animal models as well as humans point to the link between the gut microbiota and mood and anxiety models, as well as the potential for psychiatric medications to directly affect the gut microbiome.»

«Both in humans and mice there is a correlation between altered gut microbiota composition and inflammaging, but the link between the two remains to be proven in humans» concludes Fransen.

Regulatory issues must be addressed before moving to human studies, Davies said, but the findings published in the August issue of the Journal of Clinical Investigation suggest that it may be possible to manipulate the bacterial residents of the gut — the gut microbiota — to treat obesity and other chronic diseases.

Changes in the composition of the gut microbiota are seen in many human diseases such IBD, a chronic, lifelong inflammatory disorder that includes Crohn's disease and ulcerative colitis.

Like plants in a garden, the diverse populations of microbes that normally line the intestinal tract, called the microbiota, are essential to human health.

The study (which also involved a colleague) may sound simple, if a little gross, but variation in intestinal microbes, known as human microbiota, is highly complex.

Kilner adds that there are potential parallels with the way the human immune system interacts with the gut microbiota: «The language in this field is now more about management than warfare.»

Trillions of bacteria exist within the human intestinal microbiota, which plays a critical role in the development and progression of IBD.

In addition, cohousing coprophagic mice harboring transplanted microbiota from discordant pairs provides an opportunity to determine which bacterial taxa invade the gut communities of cage mates, how invasion correlates with host phenotypes, and how invasion and microbial niche are affected by human diets.

The goal of the study was to explore whether fecal microbiota from human IBS patients with diarrhea has the ability to influence gut and brain function in recipient mice.

«It's increasingly clear that our gut bacteria, or microbiota, can communicate with the human brain,» said Kathy Magnusson, a professor in the OSU College of Veterinary Medicine and principal investigator with the Linus Pauling Institute.

The work «represents a significant step in understanding human microbiota coevolutionary history,» says Justin Sonnenburg of Stanford University in Palo Alto, California, who was not involved with the research.

Known as «microbiota,» these bacteria have a vital role to play in human health: they are central to our metabolism and well - being.

Fu notes that the human body and its microbiota have evolved to live in harmony over millions of years.

People with diets high in fat, for example, have a different microbiota than do vegans, though in humans it is far more difficult to identify a core microbiota.

«Previous studies in mice have indicated that bacteria that are able to encroach upon the epithelium might be able to promote inflammation that drives metabolic diseases, and now we've shown that this is also a feature of metabolic disease in humans, specifically type 2 diabetics who are exhibiting microbiota encroachment.»

Given that the investigators have previously shown the influence of the host molecular clock on the gut microbiota, they will also ask if taking this NSAID at different times of day might lead to higher efficacy and less side effects in animal models and eventually in humans.

Although the fucose findings are still preliminary, unlocking the role of this sugar in competitions between gut microbiota and pathogens could theoretically give rise to new therapies for treating human illness.

In order to find out which bacterial species may be present in the air and on the surfaces inside spacecraft and how the composition of the microbiota may change during human habitation, a crew of six male «Marsonauts» lived inside a mock - up spacecraft, located in Moscow, from 3rd June 2010 to 5th November 201In order to find out which bacterial species may be present in the air and on the surfaces inside spacecraft and how the composition of the microbiota may change during human habitation, a crew of six male «Marsonauts» lived inside a mock - up spacecraft, located in Moscow, from 3rd June 2010 to 5th November 201in the air and on the surfaces inside spacecraft and how the composition of the microbiota may change during human habitation, a crew of six male «Marsonauts» lived inside a mock - up spacecraft, located in Moscow, from 3rd June 2010 to 5th November 201in Moscow, from 3rd June 2010 to 5th November 2011.

While a core microbiota of the same bacteria was present in all areas of the mock - up spacecraft, the authors noticed specific bacterial signatures for each individual area, or module, indicating that — much like in other indoor environments — microbial presence is associated with human presence as well as the type of activity that an area is used for.

There is increasing awareness that the intestinal microbiota, the vast, diverse population of microorganisms that inhabits the human intestines, play a role in driving colorectal cancer.

Human intestinal flora, known as microbiota, can be considered as an additional organ in the body.

Heiman and Greenway describe how the reduction in dietary diversity has changed the richness of human gut microbiota, the community of microorganisms living in the gut.

«Reduction in dietary diversity impacts richness of human gut microbiota: Dietary diversity necessary for a healthy gastrointestinal microbiome.»

The intestinal microbiota of healthy humans progressively develops in complexity from birth until adulthood, where a stable microbiome is established for the majority of an individual's adult life (Arumugam et al., 2011; Jalanka - Tuovinen et al., 2011; Durbán et al., 2012).

The findings illuminate the specialized roles played by key members of the vast microbial community living in the human gut, and could inform the development of tailored microbiota transplants to improve intestinal health after antibiotic use or illness.

Mammals — humans included — depend on their microbiota, the collection of microorganisms they host in and on their bodies.

Functional metagenomics: a high throughput screening method to decipher microbiota ‐ driven NF ‐ κB modulation in the human gut

Investigating mouse models for biological for research The congress aims to promote the International Mouse Phenotyping Consortium (IMPC) mouse lines, importance of mouse phenotyping & clinical and drug discovery collaboration, to present progresses performed by IMPC with regards CRISPR editing genome, rare diseases, microbiota and ageing pipeline, as well as illustration of examples of scientific projects about «Animal models for human diseases» and recent developments in mouse models phenotyping imaging.

BIOASTER conducts innovative collaborative research, with and for public and private partners in the four major application fields of microbiology including human and veterinary infectious diseases: vaccines, antimicrobials, diagnosis and microbiota.

Of special note today: gut microbiota species expressing orthologs of human Ro60 might be involved in triggering and sustaining chronic autoimmunity in lupus; The portal vein blood microbiome in patients with liver cirrhosis; A randomized clinical study suggests dietary promotion of short chain fatty acid producing gut microbes as an effective treatment for type 2 diabetes; and the sexual dimorphism of root, flower and leaf microbiomes in the wild strawberry plant

Methodology challenges in studying human gut microbiota — effects of collection, storage, DNA extraction and next generation sequencing technologies — Marina Panek — Scientific Reports

In a study published as a letter to the journal Gut, the team outline new evidence suggesting that the human genome may play a role in determining the makeup of the billions of microbes in the human gastrointestinal tract collectively known as the gut microbiotIn a study published as a letter to the journal Gut, the team outline new evidence suggesting that the human genome may play a role in determining the makeup of the billions of microbes in the human gastrointestinal tract collectively known as the gut microbiotin determining the makeup of the billions of microbes in the human gastrointestinal tract collectively known as the gut microbiotin the human gastrointestinal tract collectively known as the gut microbiota.

We are interested in developing and applying bioinformatics methods to study the intricate interactions between host (e.g., human and mouse) and microbes (pathogens or bacterial microbiota).

Spurred by this finding, Littman's team examined the gut microbiota in patients with rheumatoid arthritis, a debilitating autoimmune disease, and found a much higher proportion of patients than healthy individuals who harbored the human intestinal bacterium Prevotella copri.

A few interesting articles in early life human microbiome, plus: A comparison between Staphylococcus epidermidis commensal and pathogenic lineages from the skin of healthy individuals living in North American and India; A new tool to reconstruct microbial genome - scale metabolic models (GSMMs) from their genome sequence; The seasonal changes in Amazon rainforest soil microbiome are associated with changes in the canopy; A specific class of chemicals secreted by birds modulates their feather microbiome; chronic stress alters gut microbiota and triggers a specific immune response in a mouse model of colitis; and evidence that the short chain fatty acids profile in the gut reflects the impact of dietary fibre on the microbiome using the PolyFermS continuous intestinal fermentation model.

The congress aims to promote the International Mouse Phenotyping Consortium (IMPC) mouse lines, importance of mouse phenotyping & clinical and drug discovery collaboration, to present progresses performed by IMPC with regards CRISPR editing genome, rare diseases, microbiota and ageing pipeline, as well as illustration of examples of scientific projects about «Animal models for human diseases» and recent developments in mouse models phenotyping imaging.

Plentiful opportunities for researchers to learn about and discuss important developments in the field of human microbiota, the collection of microbes living in and on our body that have a significant impact on human health and well - being.

* Potential and active functions in the gut microbiota of a healthy human cohort — Alessandro Tanca — Microbiome