Sentences with phrase «in human obesity»

Interindividual variation in posture allocation: possible role in human obesity.

This gene, which the companies believe is involved in regulating how the body stores and uses energy, implicates a novel pathway in human obesity.

Elevated circulating levels of succinate in human obesity are linked to specific gut microbiota — Carolina Serena — The ISME Journal

Reduced adipose tissue oxygenation in human obesity.

Not exact matches

This has not been shown in humans but may spark additional research in the battle against obesity.

This factor is being touted as having great potential towards reducing obesity in humans.

In addition to reducing the chance of obesity and improving mental health, gardening is relaxing and helps us engage with our human roots.

Human milk is low in protein compared to other milks and formula which appears to lead to decreased risk of obesity.

I think that medicalized birth practices resulting in inter-generational deprivation of our basic human rights has been a major contributor epidemics of diabetes and obesity and mental health problems.

Because HUMAN Healthy Vending co-founders Sean Kelly and Andy Mackensen know that there is a link between low access to nutritious foods and childhood obesity, they are on a mission to place these machines in areas where people need access to healthful meals the most, including in areas designated as food deserts.

We know there is so much more to do in solving the problem of childhood obesity and in bringing healthy food to food deserts; so, we're just getting started,» said Andy, HUMAN's managing partner.

Two are the Office of Minority Health in the Department of Health and Human Services, and HBO, which produced the Weight of the Nation obesity documentary I discussed a few weeks ago.

Low levels of physical activity and inefficient sleep patterns intensify the effects of genetic risk factors for obesity, according to results of a large - scale study presented at the American Society of Human Genetics (ASHG) 2017 Annual Meeting in Orlando, Fla..

«Alterations in the gut microbiota are associated with obesity and the metabolic syndrome in both humans and rodents,» Shulman noted.

Segal says that the global rise in sweetener consumption — along with other major shifts in human nutrition — coincided with the dramatic increase in obesity and diabetes epidemics around the world.

Similarly, jet lag in two humans who had traveled from the United States to Israel changed the composition of gut microbes, favoring the growth of bacteria that have been linked to obesity and metabolic disease.

«Our findings confirm in humans what has been shown in animal models — that maternal obesity has a more significant impact on the body composition of boys than girls,» said Dr. Andres.

Obesity in animals, including humans, is not dependent on the amount of body weight, but on the amount of body fat - specifically adipose tissue.

«We wanted to investigate whether human adults had the ability to transform some white fat deposits into beige fat when they were exposed to cold,» said one of the study's authors, Philip A. Kern, MD, of the University of Kentucky School of Medicine in Lexington, KY. «Browning fat tissue would be an excellent defense against obesity.

With global increase in obesity and diet - related metabolic diseases, interest has intensified in ancestral or «Palaeolithic» diets, not least because — to a first order of approximation — human physiology should be optimized for the nutritional profiles we have experienced during our evolution.

If it can be shown to work in humans, it could decrease obesity, lengthening life.

Mice without the leptin gene, called ob / ob, overeat, weigh in at three to four times normal, and develop symptoms similar to the obesity - related diabetes seen in humans.

In humans, too much fructose puts the liver at risk for conditions such as fatty liver disease, and raises the overall risk of obesity and type 2 diabetes (SN: 10/5/13, p. 18).

Similar alterations in humans taking antibiotics, especially children, might be adding to the obesity epidemic

If the therapy can be improved and shown to work well in humans, it could be an entirely new way to help battle obesity, diabetes and related conditions.

Regulatory issues must be addressed before moving to human studies, Davies said, but the findings published in the August issue of the Journal of Clinical Investigation suggest that it may be possible to manipulate the bacterial residents of the gut — the gut microbiota — to treat obesity and other chronic diseases.

Comparative anatomy and human evolution experts from the University's School of Medicine have been studying the correlation between meat consumption and obesity rates in 170 countries.

This pattern of weight gain and insulin resistance parallels the development of obesity and Type 2 diabetes in humans, Hinton said.

If acetate does the same in humans, dietary fibre may hold the key to curbing appetites and perhaps help battle obesity — although boosting our intake might not be the best way to see an effect.

In the study, the scientists examined the human serotonin receptor, which plays a role in learning, mood and sleep and is the target of drugs that combat obesity, depression and migraineIn the study, the scientists examined the human serotonin receptor, which plays a role in learning, mood and sleep and is the target of drugs that combat obesity, depression and migrainein learning, mood and sleep and is the target of drugs that combat obesity, depression and migraines.

«Knowing which microbes live in various ecological niches in healthy people allows us to better investigate what goes awry in diseases thought to have a microbial link, like Crohn's disease and obesity,» says George Weinstock, associate director of the Genome Institute at Washington University in St Louis and one of the Human Microbiome Project's principal investigators.

He explained that rimonabant, a drug which blocked endocannabinoid signaling at cannabinoid receptors, was on the market in Europe for the treatment of human obesity.

DiPatrizio and Argueta caution that further research is necessary to identify whether similar mechanisms drive obesity in humans.

For example, researchers reported in a much touted 2006 Science article that they had discovered a gene variant that seemed to confer a risk for obesity, and they replicated the results in four human populations.

Kajimura is hopeful but cautious about the prospects for using these drugs to treat human obesity in the near future.

It is exciting that there is now evidence that brown fat can be useful in treating obesity in adult humans,...

«The BDNF gene has previously been linked to obesity, and scientists have been working for several years to understand how changes in this particular gene may predispose people to obesity,» said Jack A. Yanovski, M.D., Ph.D., one of the study authors and an investigator at NIH's Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).

Given the importance of this discovery, the researchers are confident they will obtain the funding needed to continue their work — says principle researcher Ahmad Agil — «and be able to achieve their final objective: to confirm these findings in humans, by administering melatonin to help combat obesity and diabetes.»

The results suggest that drugs capable of targeting similar molecular pathways in human fat cells could one day become major tools for fighting the growing worldwide epidemics of obesity and type 2 diabetes, according to senior investigator Shingo Kajimura, PhD, an assistant professor of cell and tissue biology in UCSF's School of Dentistry.

Their analysis — which used DNA data from a Neandertal woman from the Altai Mountains in Siberia (SN: 1/25/14, p. 17) and 112,338 present - day British people — confirmed some links between Neandertal heritage and human diseases made by previous studies (SN: 3/5/16, p. 18), but didn't find evidence that Neandertal gene variants contribute to obesity.

The researchers are now examining whether CK2 - inhibitors can effectively reduce obesity as well as prevent it, and whether they can be used alongside next - generation drugs that mimic the effects of cold to trigger brown fat to burn energy in humans.

From that perspective, it becomes clear that humans are prone to obesity because our bodies evolved in an environment of scarcity, where consuming as much high - energy food as possible was a useful survival strategy.

The researchers note that while some genes involved in obesity could already have been implicated in other aspects of human health, others could be part of pathways that are not yet understood.

By analyzing genetic samples for over half a million individuals as part of the GIANT research project, which aims to identify genes that regulate human body and size, researchers found more than 100 locations across the genome that play roles in various obesity traits.

«Since BPA has also been linked to obesity in humans, people need to be aware that environmental factors can lead to increased susceptibility to obesity and cardio - metabolic disorders.»

But in the past decade, researchers have come to appreciate that the bacteria living in and on our bodies — collectively called the human microbiome — play a role in how our bodies work, affecting everything from allergies to obesity.

«The addition of osteocalcin as a metabolic regulator may one day lead to novel therapies, but we need to understand much better how it works and how it fits into physiology before such therapies can be attempted in humans,» says endocrinologist Mitch Lazar, director of the Institute for Diabetes, Obesity, and Metabolism at the University of Pennsylvania.

Satellite studies of outdoor lighting have also found an increased risk of obesity in humans who live in highly lit areas.

Acute sleep loss in humans is associated with increased appetite and insulin insensitivity, while chronically sleep - deprived individuals are more likely to develop obesity, metabolic syndrome, type 2 diabetes, and cardiovascular disease.

A hormonal imbalance could lead to overeating; indeed, obesity runs rampant in certain human families that have a genetic deficiency in leptin.