Patients using the pump also spent on average almost 3 hours less every day
in hyperglycaemia (when blood sugar becomes too high).
Not exact matches
With regard to microvascular complications, the authors say that «a refocus towards intensive management of
hyperglycaemia at diagnosis, particularly
in younger people, may be warranted if the long - term risk of microvascular complications is to be minimised.
The most common, more severe adverse event (grade 3) was
hyperglycaemia, which was observed
in 14 % of patients.
One of the greatest health concerns
in developed countries is the increase
in obesity, diabetes, and metabolic syndrome, which is a combination of high blood pressure (hypertension), blood sugar (
hyperglycaemia), and cholesterol (dyslipidemia) along with increased belly fat.
Research is underway to evaluate these closed - loop systems
in the very young,
in pregnant women with type 1 diabetes, and
in hospital
in - patients who are suffering episodes of
hyperglycaemia.»
Chronic treatment with a glucokinase activator delays the onset of
hyperglycaemia and preserves beta cell mass
in the Zucker diabetic fatty rat.
A cross-sectional study of glucose regulation
in young adults with very low birth weight: impact of male gender on
hyperglycaemia
Conversely, within non-diabetic populations, periods of IER (75 - 85 % ER on restricted days) do not typically affect fasting glucose levels 37, 41, 45, 48 or HbA1c 41, 48; results of which can often be replicated by short term CER studies.62 - 65These findings are unsurprising given that frank
hyperglycaemia within the T2DM diagnostic range is effectively a late - stage manifestation of IR, which along with compensatory increases insulin secretion, can precede the onset of T2DM by many years.66, 67 Findings from one large scale prospective cohort study, Whitehall II, reveal a sharp increase
in the trajectory towards fasting
hyperglycaemia which is only detectable three years prior to diagnosis with T2DM.67 Consequently, it can be argued that changes
in circulating insulin concentrations, fasting (hepatic) insulin sensitivity and glucose uptake / clearance are more sensitive markers of deteriorating glucose control than fasting glycaemia
in non - diabetics.68 - 70
«Postprandial
Hyperglycaemia as an Eitiological Risk Factor
in Vascular Failure,» Cadiovascular Diabetology, 8, 23.
Hyperglycaemia is associated with all - cause and cardiovascular mortality
in the Hoorn population: the Hoorn study
In the past two decades several medical treatments that exert their effects despite
hyperglycaemia have been derived from the experimental pathogenetic concepts of diabetic neuropathy.