Sentences with phrase «in immune»

Epigenetically - effected hypothalamic GnRH secretion is central to my model of nutrient - dependent pheromone - controlled adaptive evolution, which was presented as «Olfactory - genetic - neuronal - hormonal reciprocity in learning, memory, behavior and in immune function» during a 1995 Anti-Aging medicine conference.

When the researchers looked at the role of genes that were methylated by genes with code differences related to ASD, including additional genes beyond those with direct code changes, they found that the majority were involved in biological pathways that were important in immune function.

Based on data from Robinson and other people who had similar experiences, Newell has been able to identify a pattern of genes turned on in their immune cells that may predict whether someone could be able to become «tolerant.»

Many of the downregulated genes are involved in the immune system — an interesting result given the recent finding that D. sechellia can't mount an immune response to an attack by the parasitoid wasp Asobara tabida.

With respect to biological applications, the group is focusing on how cellular heterogeneity and cell - to - cell communication drive ensemble - level decision - making in the immune system, with an emphasis on «two - body» interaction (e.g., host cell - virus interactions, innate immune control of adaptive immunity, tumor infiltration by immune cells).

«The collaboration is important for Biotecnol's strategy of working with top cancer institutions in the immune - oncology field which will accelerate the development of cutting - edge therapeutic approaches to fight cancer.»

«It was known that acute exposure to pyrethroids could lead to immune dysfunction, and that the molecules they act on can be found in immune cells; now we need to know more about how longer - term exposure affects the immune system in a way that increases risk for Parkinson's.»

Systems analysis can extend further than vaccinology in immunosenescence research and, indeed, the emerging and exciting field of «immunomics» has vast potential for characterising age - associated alterations in immune function.

Ongoing projects are directed toward understanding the role that the alpha2 beta1 integrin plays in immune modulation in the tumor microenvironment.

She holds a Tier 2 Canada Research Chair in Aging & Immunity, and investigates how changes in the immune system of older adults and vulnerable populations predispose them to pneumonia infection.The aim of Dr. Bowdish's research at McMaster University is to develop novel preventative and therapeutic strategies that reduce the burden of pneumonia.

«The catalogue of genes involved in immune defence responses is well conserved among different bee species regardless of their level of social organisation,» explained Dr. Robert Waterhouse from the University of Geneva and the SIB Swiss Institute of Bioinformatics, «but it is much smaller than in solitary insects such as flies and mosquitoes that often live in more pathogen - rich environments.»

We do not want to say that blood pressure medicine can cure toxoplasmosis, but we have discovered a new signalling pathway in immune cells that is linked to their motility and that the parasite utilizes in a very smart way.

Exposing the samples from the blood bank to peptide sequences from certain gut and soil bacteria and a species of ocean algae resulted in an immune response to HIV (Immunology, doi.org/kgg).

In asthma there is a constriction of the airways and an increase in immune activation — typically these are treated with a dilator (salbutamol) and a steroid (to reduce immune response).

«Our team discovered an enzymatic pathway that converts omega -3-derived endocannabinoids into more potent anti-inflammatory molecules that predominantly bind to the receptors found in the immune system,» Das said.

PEOPLE who suffer long - term infection with hepatitis B may have a genetic weakness in their immune response to the virus, say researchers in Britain and Qatar.

The multidisciplinary Southampton team, led by Dr Jessica Teeling, and in collaboration with Lundbeck (a multinational pharmaceutical company based in Denmark), engineered three antibodies to change the way they engage cells in the immune system.

At the same time, the drugs can spark a reduction in immune system cells known as T regulatory cells (Tregs), which usually tamp down the immune response to disease or infection.

Almo's group, for instance, is now investigating proteins involved in the immune system, to look for molecules that could be useful as drugs or drug targets.

«The method enables us to manipulate cells into producing proteins that are suspected to be involved in the immune system.

Numerous changes were also observed in the immune and cardiovascular systems, whereas the digestive system remained relatively unchanged.

This will help us to focus on how the genetic changes act in those immune cells to cause disease.»

A T - cell marker panel that can identify subsets of tumor - associated T - cells allows scientists to identify and target subpopulations of T - cells playing unique roles in the immune response against a tumor.

Since HIV infection itself alters epigenetic processes in the immune system, the research team wondered whether a distinct DNA methylation profile, a major epigenetic modification where methyl groups are added to DNA, occurs in those with HIV associated - cognitive impairment and whether it exists in distinct immune cell populations from the blood.

Other investigational therapeutics historically piloted in pet dogs with cancer include muramyl tripeptide, an immune - stimulating agent that could not be tested in immune - deficient mice or rats with induced cancers, Fan said.

Cannabinoids bind to two types of cannabinoid receptors in the body — one that is found predominantly in the nervous system and one in the immune system, Das said.

Although these developmental roles are well documented it is less clear how competent these cells are to respond to infection and whether they play a significant role in the immune response of the embryo.

«We can demonstrate that there is a profound change in the immune activity in the brain» after surgery, Eriksson says.

In further studies, they plan to explore the role of autophagy in immune reactions toward other tumor cell types, to determine whether such therapies might be effective in a broad range of cancers.

The researchers determined that the virus did indeed activate many genes involved in the immune response.

Previous studies have shown an association between high folic acid intake and a reduction in the immune system defenses needed to fight viral infections and cancer.

It was only by looking across the whole human genome that we were able to identify the function of P - TEFb in the immune system, offering potential new treatments for autoimmune conditions.»

Carroll's team wondered if changes in the immune system in lupus patients were directly causing these symptoms from a pathological standpoint.

Another group, led by molecular biologist Gregory Hannon of Cold Spring Harbor Laboratory, New York, knew that a set of seven microRNAs showed up in some immune system tumors.

Both of these compounds, which are called stilbenoids, worked in synergy with vitamin D and had a significant impact in raising the expression of the human cathelicidin antimicrobial peptide, or CAMP gene, that is involved in immune function.

Breast cells become cancerous when they express Env, a viral gene that contains a growth - promoting genetic sequence expressed in immune cells.

Research in the UCR School of Medicine laboratory of David Lo found that certain cells of the epithelium have a potentially important role in immune surveillance — creating an electrostatic repulsion field to microbial invasion.

Their importance in the immune response could be one reason those pathways have survived through millions of years of separate evolution of these species.

Allergies are like false alarms in the immune system.

Lo's laboratory has for more than a dozen years studied immune responses in the gut and airways, focusing particularly on cells which function as an early warning in the immune system.

To measure the differences in immune system function between the two groups of older mice, the researchers examined the lungs to assess damage, counted the number of bacteria in the lungs, and calculated the number of the white blood cells (neutrophils).

Hojo's group is now looking for ways to block TGF - b's tumor - promoting ability without curtailing its effectiveness at reining in the immune system during transplant operations.

«This is because the stress led to poor function against the cancer by T - cells, which are very important in the immune system's control and surveillance of tumours and are a major target in many immunotherapy treatments.»

A clear contrast in immune response to TB between groups of African and Eurasian descent indicates that drug trials should take ethnicity into account

«Changes in immune regulation and increased inflammation also impact the brain, brain functioning and behaviour.

«We study the role of certain epithelial cells in the immune system.

A snippet of genetic code normally expressed in immune system cells can trigger the disease when its part of a virus's DNA.

Neutrophils play an important role in our immune system to protect us against infections.

Genome studies show that several such viruses, including one that infects mouse mammary cells and has been linked to cancer, have something in common — a sequence of DNA similar to that found in immune system cells.

It is important to point out that the region of the 5qll chromosome contains various known genes that play a role in immune response.