Sentences with phrase «in immune surveillance»

These allogeneic cells have the potential to participate in immune surveillance for breast or other cancers as observed in clinical hematopoietic stem cell transplantation.

Italian and American researchers report that the PD - 1 (programmed cell death protein 1) / PD - L1 (ligand 1) axis is a key player in immune surveillance in hematologic malignances.

Research in the UCR School of Medicine laboratory of David Lo found that certain cells of the epithelium have a potentially important role in immune surveillance — creating an electrostatic repulsion field to microbial invasion.

These antibodies are typically involved in immune surveillance, but in this case they promote the myelination of axons.»

Not exact matches

«The cells we found perform immune surveillance and contain the virus in the key battlefield where infection occurs, which is the dermal - epidermal junction,» said Zhu.

When ICZ binds to and activates the Aryl hydrocarbon receptor (AHR) in the intestinal lining, it aids in maintaining a healthy balance in the gut flora and immune surveillance, and enhances host barrier function, according to the researchers.

«Promising way to boost body's immune surveillance via p53 in fight against cancer.»

In other words, bacterial prions, could boost bacteria's ability to cause disease, evade immune system surveillance and elude drugs.

Using the JEDI technology, Mount Sinai researchers uncovered evidence that immune cells can find cells in the brain expressing their target antigen, even in non-infected states, which provides evidence of an immune surveillance pathway within the body's central nervous system.

The authors said that this result suggests that the reason bacterial numbers are so high in these mice, and, by extension, human LAD patients, is not because of a defect in the immune system's surveillance mechanism but because of the inflammation caused by the immune system's abnormal response to normal levels of bacteria in the gums.

The immune system plays a critical role not only in fending off pathogen attack, but also in cancer surveillance, and more recently as a tool in immunotherapy - based treatments.

In turn, it appears microbes on the skin tweak the complement system, as well as immune surveillance of the skin.

«This is because the stress led to poor function against the cancer by T - cells, which are very important in the immune system's control and surveillance of tumours and are a major target in many immunotherapy treatments.»

«This is a whole new way of looking at immune surveillance in the epithelium of the human gut and airway,» said Lo, a distinguished professor in the medical school's Division of Biomedical Sciences.

After an initial acute disease state, that is kept in check by host immune response, bacteria as Pseudomonas aeruginosa and Staphylococcus aureus can establish persistent infections and colonize the host by evading immune surveillance.

Interestingly tumor cells, whilst not allogeneic, are in many cases both «altered - self» and immunogenic but often actively modulate immune responsiveness to evade immune surveillance 76.

«The study of PD - 1 / PD - L1 axis in hematologic malignancies highlighted the importance of immune surveillance to cure these diseases.

As a postdoctoral fellow in the Department of Biochemistry at Trinity College, Dublin, she uncovered a new adapter molecule and new immune surveillance receptors, and was subsequently awarded a Wellcome Trust International Research Fellowship.

«If exercise indeed strengthens the immune system and potentially improves cancer surveillance, it's one more thing we should educate patients about as a reason they should schedule regular activity throughout their day and make it a priority in their lives.»

Allogeneic cells, particularly mismatched or haploidentical cells, in the context of hematopoietic transplantation have been found to provide potent immune surveillance for both hematologic and solid tumor malignancies in a process referred to as graft - versus - tumor [13]--[15].

One possible role of FMc in healthy women might be the provision of allogeneic immune surveillance for (pre --RRB- malignant cells.

Warren Alpert Foundation Honors Five Pioneers in Cancer Immunology Scientists recognized for seminal discoveries in cancer's ability to thwart immune surveillance that paved the way to immune - based cancer therapies.

Residing in the epithelial cells that line our skin and gut are specialised T cell compartments that run tight immune surveillance on local tissues.

By integrating the aforementioned observations of FMc in autoimmunity and transplantation immunobiology, we reasoned that allogeneic FMc might provide immune surveillance for breast cancer in parous women.

In the hours following intense exercise, the ability of the immune system to conduct good surveillance of the body is easily compromised, and for this reason, sufficient protein intake to restore healthy immune function can be important.

In turn, it appears microbes on the skin tweak the complement system, as well as immune surveillance of the skin.

An important function of the immune system is in tumor surveillance and this function may be decreased in Shar - Pei.