The best education consists
in immunizing people against systematic attempts at education.
«This shows that the vaccine induced a protective response
in the immunized monkeys.
Forty days later, the tumors
in the immunized mice were one - tenth the size of those in the animals that did not get the vaccine.
In this study, the anti-HIV immune responses
in immunized llamas were studied via deep sequencing analysis using broadly neutralizing monoclonal HCAbs as a guides.
Notably, a population of sequences with identity to J3 greater than the germ line precursor (85.6 %) is found only
in immunized llama 8 which produced the J3 HCAb (population above the dotted line in Fig. 5C right - hand panel compared to naïve llama 3 sequences shown in left - hand panel).
(A) Prior to infection, total IFN - γ — producing gp33 - specific CD8 T cells per spleen (CD90, CD8, CD44, IFN - γ) as represented by IFN - γ production in response to gp33 peptide restimulation
in immunized and control mice (n = 3).
Serum levels of the proinflammatory cytokines IL - 6 and TNF - α were unchanged
in immunized mice, whereas the anti-inflammatory cytokine IL - 10 was significantly depressed (Fig. 2A).
Then 30 d after priming the CD8 T cell memory response, we compared the development of HLH
in immunized and control mice prior to LCMV infection.
We considered that the apparent loss of efficacy of IFN - γ blockade
in immunized mice might be explained by increased IFN - γ production and therefore an underdosing of blocking Ab and incomplete IFN - γ blockade.
To test this hypothesis, TNF - α and IFN - γ were blocked in gp33 - immunized mice to determine whether dual blockade would enhance survival
in immunized mice.
Serum levels of IFN - γ were significantly elevated
in immunized mice compared with controls.
Unlike IFN - γ blockade, which lost effectiveness in immunization - enhanced HLH, ST2 blockade remained equally effective
in immunized and control mice, with equivalent survival in both immunized and control mice to up to 18 d postinfection (Fig. 3C).
For gp33 - immunized mice, average survival after LCMV infection decreased from 14 d in control mice to 9 d
in immunized mice (Fig. 1B).
(A) Serum cytokine levels
in immunized and control mice (n = 8 — 12).
The total number of TNF - α — producing gp33 - specific CD8 T cells
in immunized mice was increased by ∼ 4-fold, a difference that remained with IFN - γ blockade (Fig. 4D).
In infected mice, absolute numbers of splenic gp33 - specific CD8 T cells
in immunized mice were increased 6-fold compared with control mice as shown by IFN - γ production with peptide stimulation (Fig. 2B).
Hepatitis was markedly enhanced
in immunized Prf1 − / − mice compared with control mice, with significantly more inflammatory lobular infiltrates (Fig. 1E).
However, these data argued that IFN - γ is not the only component leading to the increased disease severity of enhanced HLH
in immunized mice.
Abetax - 40 levels were elevated approximately 2 - to 5-fold in plasma and decreased up to 64 % in CSF
in immunized vervets.
While we found positive relationships between asexual multiplication and virulence across all the lines including the ancestral ones (Figure 3A), the I - lines and N - lines were statistically indistinguishable (p > 0.05) for (i) parasitemia on day 4, (ii) parasitemia on day 6 or 7, (iii) the increase in parasitemia from day 4 to day 6 or 7, and (iv) maximum parasitemia, with one exception: maximum parasitemia was significantly higher in I - lines than N - lines derived from unadapted ancestors when measured
in immunized mice, and this only in one of the two replicate experiments (23 % versus 6.9 % parasitemia, p < 0.001).
Ancestral pretransmission lines had similar levels of virulence in the separate pretransmission and posttransmission experiments, with the exception of the preadapted ancestral line
in immunized mice, which had higher virulence in the latter than the former (p = 0.002).
Regression analysis for both traits showed significant (p < 0.001) and similar (p > 0.05) slopes within both naïve and immunized mice, and significantly lower (p < 0.001) maximum parasitemia and gametocyte production
in immunized than in naïve mice.
Our data are consistent with this idea, since mosquito transmission eliminated the difference between the I - lines and N - lines
in immunized mice but not in naïve mice, suggesting that part of the virulence advantage
in immunized hosts was due to novelty in the clonally variant surface antigens.
No deaths occurred during the pretransmission experiments, but in addition to the one death that occurred early in the infection prior to the occurrence of any weight loss or anemia (excluded from analyses), five occurred in the posttransmission experiment, four of these in naïve mice (two in the N - lines, one in the I - lines, and one in the nontransmitted ancestral line, all derived from the preadapted line) and one
in an immunized mouse (preadapted, nontransmitted ancestral line).
Additional vaccine doses
in an immunized animal do not increase or improve the immunity, but they do increase the risks.
Not exact matches
There was no racial intent
in my remarks - false, defamatory charges of racism are a transparent attempt to
immunize entertainment and sports elites from scrutiny and criticism.»
Congress obliged the banks by authorizing interstate banking
in 1994, repealing Glass - Steagall
in 1999, and
immunizing derivatives from state and federal gambling laws
in 2000.
In the meantime, American banks have had more time to immunize themselves from potential European defaults, further reducing the risks that a blowup in Europe could cause financial panic in the U.
In the meantime, American banks have had more time to
immunize themselves from potential European defaults, further reducing the risks that a blowup
in Europe could cause financial panic in the U.
in Europe could cause financial panic
in the U.
in the U.S.
Hedgers try to
immunize themselves against a future change
in the rate.
Since its launch
in 2000, GAVI has helped
immunize 370 million children
in the poorest countries.
§ § 554.01 — 554.05 (1994) Lawful conduct or speech that is genuinely aimed
in whole, or
in part, at procuring government action, unless constituting a tort or violation of a person's constitutional rights, is
immunized under the law.
A better option for everyone, people with and without cancer alike, would be to find a cure to the disease so that everyone
in the future can be
immunized against it.
Thanks to largely American military efforts, they were able to bring
in oral rehydration salts to add to clean water dropped by air... they
immunized every child under 5 yrs against measles, which is the biggest killer
in these circu.mstances.
(i) the question of gay rights — funny I agree with gay rights, must be a political debate at its heart (ii) a wonan's right to choose — funny I agree with this, see above thought (iii) teaching evolution
in school — again I agree (iv) my ability to buy a glass of wine on Sunday — definitely politics here (v)
immunizing teens against HPV — got my kids
immunized, not even politics here (vi) population control — this is religions fault??? no this is cultural (vii) assisted suicide at end of life — agree with that, still have my religion (viii) global warmning — agree it needs to get fixed, doesn't have anything to do with religion
She was poking fun at this language, but her point was serious: if even
immunizing kids has to be defended through market language, the progressive idea is
in deep trouble.
And when it comes to
immunizing such «choices» from legal restriction or even private remonstration, the Court's liberals can be counted upon to flip on the switch of what Justice Antonin Scalia, writing
in dissent, describes as «the ad hoc nullification machine that [is] set
in motion to push aside whatever doctrines of constitutional law stand
in the way of the highly favored practice of abortion.»
In all four traditions, we are not made into free persons by becoming autonomous selves who have been
immunized from all obligations that we have not independently chosen.
According to chili historian F. Starr, «Cincinnati chili was concocted
in October, 1922, by a man who had never eaten a bit of Texas chili, and it has been made ever since by people
immunized against it by geography and culture.»
«We've all but conquered paralytic polio
in this country, and what's the point of
immunizing against one crippler if we permit our children to risk paralysis as the result of trampoline accidents?»
Sugar water is often given to babies while they are being
immunized in order to keep them calm.
I had a nasty cold when my son was vey young and was concerned about passing it on, and was assured by a clinic nurse that the antibodies I was passing on
in my breast milk would
immunize him, so no need to worry.
Just as you protect your kids against illnesses like measles, you can help «
immunize» them against drug use by giving them the facts before they're
in a risky situation.
Therefore, parents need to exercise greater caution
in protecting their babies and ensuring that they are
immunized properly.
Dogs
in the park would be required to be healthy, fully
immunized and display current park district and village ID tags on their collar if applicable, officials said.
In addition, we chose not to immunize my son Jason and if you choose the same, I can help you obtain a legal religious exemption recognized in New York Stat
In addition, we chose not to
immunize my son Jason and if you choose the same, I can help you obtain a legal religious exemption recognized
in New York Stat
in New York State.
The vaccine is believed to be extremely effective at preventing HBV, as long as a person,
in this case your baby, is
immunized before contracting the virus.
Maybe he has an ear infection
in one ear, or maybe the side that he was just
immunized on is tender, for example.
So if you were wondering why your baby is scheduled to be
immunized for a whopping 14 diseases
in her first year of life, think about this: The reason these ailments sound so outdated is because of the success of vaccines.
For getting the child
immunized at the right time, you need to maintain a schedule, and an immunization chart helps you
in this regard.
Evidence shows babies who've been
immunized in accordance with recommendations from the American Academy of Pediatrics and the CDC have a 50 % reduced risk of SIDS compared with babies who aren't fully
immunized.