Sentences with phrase «in immuno»

Genocea's pipeline includes GEN - 003, a novel T cell - enabled immunotherapy for genital herpes currently in Phase 2 clinical development, and earlier - stage investments in immuno - oncology.

Toxoplasma do rarely cause disease in immuno - suppressed cats.

Infection with toxoplasmosis, a one - celled parasite, may cause blindness, pneumonia and nervous system disease in immuno - compromised people, and blindness and mental retardation in unborn babies of infected women.

Expansion of the Research Centre, creation of the Integrated Cancer Centre and innovative patient care projects in immuno - oncology, vision health, nephrology and cellular therapy

Circulating autoantibodies are powerful resources to aid in the diagnosis and treatment of autoimmune disorders, infectious diseases and cancer - especially with promising advances in immuno - oncology.

The CRI iAtlas database is the first comprehensive effort in immuno - oncology to address the recent National Cancer Moonshot Blue Ribbon Panel recommendation to establish a pan-cancer immune atlas that would help catalyze new research in cancer immunotherapy.

«Like CRI, we at BMS are committed to advancing research in immuno - oncology and making treatment with immunotherapy available to more people with cancer.»

We're driving discovery research in immuno - oncology which is leading to new and exciting immunotherapeutic possibilities.

iTeos» pipeline addresses key unmet needs in immuno - oncology: the inhibition of immune suppression in inflamed (hot) tumors and the increase of immunogenicity in non-inflamed (cold) tumors.

The project associates the expertise of IRIBHM in GPCR discovery and validation, the unique technology on sensory GPCRs developed by ChemCom, the in - depth tumor immunology expertise of de Duve with the drug discovery capabilities of iTeos and the expertise of ImmunXperts with human primary cells in immuno - oncology.

Affigen's team houses deep expertise in immuno - oncology, mass - personalized biomolecular engineering and complex therapeutic development.

The researchers are organized in different expert focus groups, based on their expertise in different cancer types and research areas in immuno - oncology.

«Our work could also contribute to ongoing efforts in immuno - oncology and the treatment of cancer,» explained Tao Xu, postdoctoral scholar in Ding's laboratory and first author of the study.

Namouni credits trailblazing and bold leadership for BMS's success in immuno - oncology.

This study tested a new combination therapy in immuno oncology and found encouraging response rates with omaveloxolone plus ipilimumab or nivolumab in patients who were checkpoint inhibitor naïve or resistant.

Much current research in immuno - oncology focuses on improving these treatments, for example, by finding new immunotherapy targets and identifying biomarkers that predict a patient's response.

For example, we've seen new discoveries in health care recently, especially in immuno - oncology therapies, which help the immune systems of cancer patients recognize and destroy cancerous cells.

Investigators have repeatedly touted the drug as a potential lynchpin in immuno - oncology, focusing on an enzyme that suppresses the immune cells Opdivo and a whole new class of PD - 1 / L1 checkpoints are designed to unleash in an attack on cancer cells.

Merck & Co. just scored a point in its immuno - oncology rivalry against Bristol - Myers Squibb.

In immuno - oncology — what might seem a classic «biotech - y» niche in Big Pharma — Bristol might actually need some heft to be a market leader.

The so - called bio-pharma player has been a pioneer in immuno - oncology, recently taking steps to further expand the business.

Not exact matches

More news on the GBM front: Tomorrow (Thursday) and Friday, the Parker Institute for Cancer Immunotherapy, is hosting a glioblastoma immuno - oncology research summit in Los Angeles — bringing together top industry and academic scientists to share their research.

These products — largely innovative and pricey specialty medications that include breakthrough Hepatitis C treatments and immuno - oncology drugs — reflect the increased productivity and improved pipelines of pharma's R&D departments in recent years.

• TCR2 Therapeutics Inc, a Cambridge, Mass. - based immuno - oncology company, raised $ 125 million in Series B funding.

Bristol's $ 2.4 billion purchase of Medarex — which pharmaceutical analysts routinely cite as one of the best acquisitions in the history of the industry — would give the company not only a new blockbuster but also a leadership position in a burgeoning drug category: immuno - oncology.

Related Articles: Merck's Keytruda held back by docs who don't want to wait for diagnostics Bristol's Opdivo - Yervoy combo ups response rates in first - line lung cancer patients Roche's Tecentriq bursts onto immuno - oncology scene, with Merck and BMS in its sights Bristol - Myers» new Opdivo ad touts biomarker advantage over Merck's Keytruda Merck's Keytruda lines up its survival data for stepped - up battle with BMS» Opdivo

«Dr. Hambleton's unique clinical background in both immuno - oncology and synthetic lethality will strengthen our organization's capabilities as we advance multiple first - in - class programs into the clinic, leveraging our clinical strategy in patient selection and combinations.»

Tesaro has a coveted position as a leader in the so - called immuno - oncology sector, which harnesses the body's own immune system to combat cancer cells.

The adjusted tally beat consensus expectations of $ 1.00, thanks in part to stronger demand for its standout immuno - oncology drug KEYTRUDA, and management responded by raising its full - year guidance.

U.S. health regulators on Tuesday granted accelerated approval for Pfizer Inc's immuno - oncology drug Bavencio to treat advanced bladder cancer, marking the second approval in less than two months for the treatment developed along with Germany's Merck KGaA.

«We are pleased to share this vision with the unique blend of crossover funds, pharmaceutical companies, and venture capital investors participating in our Series B, and look forward to advancing our position as the leading biotech with a dual focus on synthetic lethality and immuno - oncology.»

He also served as Global Head of the Immuno - Oncology Translational Innovation Platform where he was instrumental in rebuilding immuno - oncology (IO) research at the company, including pruning and re-orienting the discovery pipeline.

first as a research analyst in a large Pharmaceutical company — working with off licence immuno suppressive drugs and latterly as... Continue reading →

We're going to probably have to put her on an immuno suppressive drug staring in November.

«There are authentic dietary supplements — multivitamins, calcium, iron — which do supplement the diet» and can help many people, says rheumatologist and immuno - logist Donald Marcus of Baylor College of Medicine in Houston, Texas, an early critic of the supplement industry.

«The treatment of multiple myeloma has improved significantly in recent years with the introduction of therapies such as proteasome inhibitors [which interfere with tumor cells» protein - disposal system] and potent immuno - modulatory agents,» said the paper's senior author and lead investigator, Paul Richardson, MD, clinical program leader and director of clinical research at Dana - Farber's Jerome Lipper Multiple Myeloma Center, and the R.J. Corman professor at Harvard Medical School.

According to a report by the industry group PhRMA, almost 250 immuno - oncology medicines and vaccines were in development in 2017.

A number of immuno - oncology therapies on the horizon tackle this problem in novel ways.

Grape - like structures of viral replication territories in the nucleus of a human cell visualized by click - chemistry and immuno - fluorescence confocal microscopy.

Protein drugs are currently used to treat arthritis, anemia, and immuno - suppression in cancer patients undergoing chemotherapy, but they have the potential to treat many more ailments.

Pedro de Noronha Pissarra, chief executive officer of Biotecnol said: «We're very proud to work with Cancer Research UK on the development of advanced clinical trial approaches in this competitive and highly promising field of immuno - oncology.

Seres Therapeutics, Inc. (NASDAQ: MCRB) today announced that new preclinical data supporting the development of microbiome therapeutics for immuno - oncology (leveraging gut microbiota to impact tumor immunotherapy) 1 will be presented today by Sceneay et al in the late breaking poster session at the 2018 American Association for Cancer Research Annual Meeting (AACR) in Chicago.

No improvement in long - term survival over time for chronic lymphocytic leukemia patients in stereotyped subsets # 1 and # 2 treated with chemo (immuno) therapy

Under the terms of the new agreement, AstraZeneca and Moderna, a pioneer of mRNA Therapeutics ™, have agreed to collaborate on two specific immuno - oncology programs, based on promising pre-clinical data, including pharmacology in tumor models.

The company showed how they first defined A2A as the receptor required for mediating the effect of adenosine on immune cells within the tumor microenvironment and reported the characterization of a novel immuno - oncology - dedicated adenosine receptor 2A antagonist that functions in the high adenosine concentration found in tumors.

The immuno - oncology revolution has spurred a renewed interest in T cell biology, including therapeutic use of T cells themselves.

Topics range from toll - like receptors and composite limb grafts to recent immuno - suppression trials and issues in the globalization of transplantation.

iTeos Therapeutics has developed a novel and potent best - in - class A2A blocker that has been specifically optimized for immuno - oncology indications to retain a high potency in the adenosine - rich environment found in tumors and to restore cytokine production even in the presence of high concentrations of adenosine.

NEMO / IKK: Targeting the interaction between NEMO and IKK to block pathological NF - kB signaling has many therapeutic applications in inflammatory and autoimmune diseases (RA, IBD, psoriasis, acute inflammatory indications, etc.) and oncology (immuno - oncology, B - cell lymphomas, and solid tumors).

The AS02A Adjuvant System is composed of an oil - in - water emulsion and 2 immuno - stimulants, 3 - deacylated monophosphoryl lipid A and QS21, a saponin agent derived from the soap bark tree, Quillaja saponaria [26], [27].