Sentences with phrase «in immunodeficient mice»

The researchers also tested a Runx2 knock - down variant of a human multiple myeloma cell line and found that it produced significantly less tumor growth in immunodeficient mice than the original human multiple myeloma cells.

In mouse models, carcinogen - induced tumors that arise in immunodeficient mice, when transplanted to wild - type mice, are usually eliminated by the intact immune system of the new host.

Presumably, tumors induced in immunodeficient mice are highly immunogenic, and therefore easily identified and removed by a healthy immune system.

Once seeded onto a proper support, these keratinocytes appeared capable of forming a pluristratified epidermis both in vitro and in vivo as xenografts in immunodeficient mice.

However, their initial finding demonstrated that progenitor derived from iPSCs generated using lentiviral gene transduction led to the high incidence of highly aggressive tumors in immunodeficient mice after transplantation under the kidney capsule.

Another study in the same issue of Nature also investigated cancer immunoediting in immunodeficient mice, this time in an oncogene - driven model of sarcoma.

In immunodeficient mice, for example, carcinogen - induced tumors develop more often and progress more rapidly than in wildtype mice.