Recently, the crucial involvement of IRFs in innate and adaptive immune responses has been gaining much attention, particularly with the discovery of their role
in immunoregulation by Toll - like receptors and other pattern - recognition receptors.
Not exact matches
This thinking may change thanks to the new finding by scientists
in the Laboratory of
Immunoregulation at the National Institute of Allergy and Infectious Diseases (NIAID), part of NIH.
As for therapeutics, Xavier, who is also the Kurt Isselbacher Chair
in Medicine at Harvard Medical School and Co-Director of the Center for Microbiome Informatics and Therapeutics at MIT, says that knowing which species are absent and which are flourishing
in the gastrointestinal tract of children with T1D may help make it possible to slow progression of the disease after onset by revealing ways to manipulate the microbiome and,
in turn, microbiome - induced
immunoregulation.
Studies suggest that the anti-inflammatory properties of melon are mainly related to its capacity to induce the production of interleukin 10 (IL - 10), an anti-inflammatory cytokine that affects
immunoregulation and inflammation processes
in the human body.
Proposed causes for human IBD include defective
immunoregulation of the gut - associated lymphoid tissue that may be precipitated by permeability defects, 14 infectious and parasitic agents, 15,16 and dietary allergies.13, 17 There is provocative evidence from clinical observations and animal models to incriminate normal luminal bacteria or bacterial products
in the initiation and perpetuation of canine IBD.18, 19 The clinical response to hypoallergenic or elimination diets suggest that dietary factors may influence the pathogenesis of canine IBD.8 - 11 The term «hypoallergenic» refers to a diet that is generally free of additives and preservatives, and contains a hydrolyzed protein source.