Sentences with phrase «in kidney cancer patients»

After clinical trials in kidney cancer patients demonstrated improved survival, it won FDA approval in December 2005.
The second clinical study COG - ANGIO (Pr Joly) demonstrated that antiangiogenics exert a direct negative impact on cognitive functions and fatigue in kidney cancer patients.

Not exact matches

MEG TIRRELL, NIGHTLY BUSINESS REPORT CORRESPONDENT: Since they were approved in 2014, drugs that stimulate the immune system have been giving new hope to patients with melanoma, kidney cancer, lymphoma and other cancers, including famously to President Jimmy Carter, who credited the drug called Keytruda with shrinking tumors that had spread to his brain.
As someone who had a cancerous kidney removed (a nephrectomy) in 2005 I know how mucH better the patient, me or Arsenal if you like, will always be with the cancer completelY cut out and gone from the body.
Half of the patients treated in this study responded to either ponatinib (typically used for certain types of leukemia) or pazopinib (a kidney cancer drug), depending on the genetic alterations identified through sequencing.
«The power of this study is that we looked at genes discovered to be over-expressed in patients» tumors and determined their function in kidney cancer, which has not been done on a large scale before,» he says.
Co-author Derek Radisky, Ph.D., a cancer biologist, then searched for prevalence of the NPTX2 gene in kidney cancer using nine public genomic datasets, representing thousands of patients, and found it to be the top aberrantly expressed gene associated with this cancer.
Lead author Christina von Roemeling, a graduate student at Mayo Clinic in Florida, used genomic profiling of nearly 100 kidney cancer patient samples to identify genes that were either over-expressed or under - expressed as compared to patient matched normal kidney tissue samples.
To further investigate the role of obesity in kidney cancer, South Korean researchers identified 1,543 patients who had undergone surgery to remove a kidney tumour between 1994 and 2008.
When the researchers zoomed in on these patients» medical histories and looked at their BMI trajectories they found that obese participants were more likely not only to develop kidney cancer, but also to die from it.
In one of the new papers, Zitvogel's group examined data for 249 lung, kidney, and bladder cancer patients, 69 of whom took antibiotics for routine reasons such as dental work or a urinary tract infection before or soon after starting a PD - 1 drug.
DNA sequencing demonstrated how cancer evolved from a primary tumor in the cervix to metastases in the kidney, liver, and ovary of a patient.
In previous studies, including recent genome sequencing of cancer patients, human SETD2 has been implicated in several cancer types, especially in renal cell carcinoma — the most common kind of kidney canceIn previous studies, including recent genome sequencing of cancer patients, human SETD2 has been implicated in several cancer types, especially in renal cell carcinoma — the most common kind of kidney cancein several cancer types, especially in renal cell carcinoma — the most common kind of kidney cancein renal cell carcinoma — the most common kind of kidney cancer.
Joachim Fandrey, a physiologist at the University of Duisburg - Essen in Germany, adds that the results suggest that nitroglycerin patches, which have a long track record in treating chest pain in heart disease patients, might boost EPO production in people suffering from anemia due to kidney disease or cancer.
«While IVC tumor thrombus occurs in only 4 - 10 % of all patients with otherwise organ - confined kidney cancer, surgery is the only cure.
«In reviewing this patient's case, I think we might have found a novel strategy of using pre-emptive steroids and sirolimus to mitigate organ rejection in transplant patients receiving cancer treatment involving PD - 1 inhibitors,» said Dr. Jhaveri, associate chief of the Division of Kidney Diseases and Hypertension in Northwell Health's Department of Internal MedicinIn reviewing this patient's case, I think we might have found a novel strategy of using pre-emptive steroids and sirolimus to mitigate organ rejection in transplant patients receiving cancer treatment involving PD - 1 inhibitors,» said Dr. Jhaveri, associate chief of the Division of Kidney Diseases and Hypertension in Northwell Health's Department of Internal Medicinin transplant patients receiving cancer treatment involving PD - 1 inhibitors,» said Dr. Jhaveri, associate chief of the Division of Kidney Diseases and Hypertension in Northwell Health's Department of Internal Medicinin Northwell Health's Department of Internal Medicine.
Kenar D. Jhaveri, MD, and Richard Barnett, MD, Feinstein Institute for Medical Research scientists and Northwell Health Department of Internal Medicine nephrologists, published a Letter to the Editor in the New England Journal of Medicine, which profiles a novel drug combination with the potential to help prevent rejection of a donor kidney in transplant patients undergoing cancer treatment.
In a preliminary trial of an unconventional vaccine, several patients rid themselves of kidney cancer, a kind of cancer that is particularly hard to cure.
Should the results of this study be repeated in the larger Phase III trial, it would lead to a new standard of care for kidney cancer patients, said Dr. Hammers, formerly of Johns Hopkins medical system, who holds the Eugene P. Frenkel, M.D. Scholar in Clinical Medicine at UT Southwestern.
Another derivative, called Allopurinol, is applied to prevent kidney blockage in gout patients and in cancer patients receiving radiation or chemotherapy.
«Cancer treatment for transplant patients discovered: Letter notes combination of steroids and immunosuppressants, combined with immune checkpoint inhibitors helps prevent organ rejection in kidney transplant patients undergoing cancer treatment.&Cancer treatment for transplant patients discovered: Letter notes combination of steroids and immunosuppressants, combined with immune checkpoint inhibitors helps prevent organ rejection in kidney transplant patients undergoing cancer treatment.&cancer treatment.»
While effective in most cancer patients, this course of treatment has been less successful in kidney transplant patients because if the immune system is activated, it causes the patient's body to start rejecting their donor kidney.
«We believe that these findings can lead to novel treatment options to prevent kidney damage and improve survival rates in cancer patients,» says Jessica Cedervall, researcher at the Department of Medical Biochemistry and Microbiology at Uppsala University.
«Potential new treatment for kidney failure in cancer patients
The data suggests that these neutrophils are promising targets for future therapies to treat kidney injury in cancer patients.
About 1 in 1,111 patients who undergo urologic surgery for conditions such as prostate cancer and kidney stones experience opioid dependence or overdose (ODO), a Loyola Medicine study has found.
Renal cell carcinoma, the most common form of kidney cancer, is expected to be diagnosed in over 60,000 new patients this year and claim approximately 14,000 lives, according to the American Cancer Socancer, is expected to be diagnosed in over 60,000 new patients this year and claim approximately 14,000 lives, according to the American Cancer SoCancer Society.
The signs of kidney damage in mice resemble those observed in cancer patients, suggesting that NETs could be a cause of kidney dysfunction also in humans.
An anti-PD-1 antibody developed by Bristol - Myers Squibb generates excitement with results from a phase I trial showing that, among 236 patients with various types of cancer, the treatment shrank tumors in 28 percent of melanoma patients, 30 percent of patients with kidney cancer, and 18 percent of patients with advanced non-small cell lung cancer.
Oncophage, the therapeutic vaccine for kidney cancer developed by Pramod Srivastava, is approved in Russia, making it the first therapeutic vaccine worldwide to be approved for patients.
Through CRI's Clinical Accelerator program, two new checkpoint inhibitor drugs, MEDI4736 (anti-PD-L1) and tremelimumab (anti-CTLA-4), are being tested in a phase I trial for patients with six different cancer types, including colorectal cancer, cervical cancer, head and neck cancer, kidney cancer, lung cancer, and ovarian cancer.
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The issue of kidney toxicity would also be bypassed in cancer patients because the course of treatment is much shorter, measured in weeks to months compared to years of treatment for diabetes patients.
At 11 a.m., on Wednesday, June 1, Edward Murphy — a 66 - year - old Osceola, IN, man who suffers from advanced kidney cancer that has spread throughout his body — became the first patient ever to be treated in the Chicago - area with gene therapIN, man who suffers from advanced kidney cancer that has spread throughout his body — became the first patient ever to be treated in the Chicago - area with gene therapin the Chicago - area with gene therapy.
[9, 10] Since that time, seven agents targeting the angiogenesis pathway have been FDA approved for use in patients with advanced kidney cancer.
From 2008 to 2014, I directed the Programs in Kidney and Testicular Cancers at the Rutgers Cancer Institute of New Jersey and currently oversee the Division of Urology's Program in Surgical Outcomes, Quality Care, and Patient Safety.
The cytokines interleukin - 2 (IL - 2) and interferon - alpha cause kidney cancers to shrink in approximately 10 % -20 % of patients, and provide durable remissions in a subset of these patients.
Dr. Kauffman specializes in the care of patients with kidney and prostate cancers and provides expertise in both robot - assisted and open operative approaches, including partial or radical nephrectomy and radical prostatectomy.
The Department of Urology's kidney cancer program continues to innovate and push research breakthroughs that will improve patient care, and the patient was enrolled in two clinical trials in which Dr. Badani is the primary investigator.
In cases such as heart disease, kidney and liver disease, immune diseases, cancer, allergies, skin disease, hair loss, neurology issues, physical therapy, and orthopedic surgery, we refer patients out to local specialists.
Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.
Global, based in Amsterdam About Blog IKCC is an independent and democratic network of patient support and advocacy organisations established with the mission of improving the quality of life of patients and their families living with kidney cancer.
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