Sentences with phrase «in lamin»

Comparing cells from children with progeria and their symptom - free parents, the team found that the progeria cells have increased chromatin «sticky note» mesas in lamin regions that are not normally marked as mesas.

Importantly, more that 400 different mutations in the lamin A gene have been reported, which are associated with a wide range of human degenerative diseases including muscular dystrophy, lipodystrophies and neuropathies.

Not exact matches

Yale scholar Lamin Sanneh notes that around 1900 there were roughly 9.8 million Christians in Africa.

Consider, for example, how often Alice Walker's The Color Purple is used in seminary teaching, or how C. S. Song, Kosuke Koyama and Lamin Sanneh draw on personal cross-cultural encounters to bring new perceptions to scriptural and theological themes.

Lamin Sanneh's article is the second in a series)

Lamin Sanneh seeks to broaden our categories horizontally, going beyond a Western worldview, while Wilbert R. Shenk sets out to broaden our historical categories vertically by going back in time.

Apologia: Contextualization, Globalization and Mission in Theological Education, by Max L. Stackhouse with Nantawan Boonprasat - Lewis, J. G. F. Collison, Lamin Sanneh, Leander Harding, Ilse von Loewenclau and Robert W. Pazmiño (Eerdmans, 237 pp., $ 14.95 paperback), is a major contribution to this growing literature.

Lamin Sanneh reviews a new work by Leslie Newbigin in which Newbigin claims the focus on the dichotomy between «knowledge» of so - called objective facts and «belief» in so - called subjective values is a dichotomy that is rationally indefensible.

On 2nd and 4 from the LSU 31 - yard - line, Connor Shaw hit receiver Justice Cunningham for a 29 yard strike that was aided by LSU defenders Tharold Simon and Lamin Barrow colliding in a glorious moment of DOINK:

Success continued on the ice in February as Christie took World Cup golds in Dresden and Dordrecht, but Lamin Deen and his four - man bobsleigh crew missed out on a World Championship medal after crashing out on the third run while sitting in fourth.

The Commissioner for Education in Yobe state, Mohammed Lamin, has disclosed that Government Girls Secondary School, GGSS Dapchi, in Bursari local government area, recently attacked by...

At Lafayette High School, former Bhutan refugee Lamin Tamang recounted how he was «kicked out» of his country in 1992 and spent 20 years in a refugee camp in Nepal before making his way to Buffalo in 2012.

In collaboration with the University of Texas Southwestern Medical Center (UTSW) in Dallas, the researchers found that the tumor - suppressive activity of geranylgeraniol was accompanied by down - regulation of HMG CoA reductase, a key enzyme in the mevalonate pathway that provides essential intermediates for the posttranslational modification of growth - related proteins such as Ras, nuclear lamins and insulin - like growth factor receptorIn collaboration with the University of Texas Southwestern Medical Center (UTSW) in Dallas, the researchers found that the tumor - suppressive activity of geranylgeraniol was accompanied by down - regulation of HMG CoA reductase, a key enzyme in the mevalonate pathway that provides essential intermediates for the posttranslational modification of growth - related proteins such as Ras, nuclear lamins and insulin - like growth factor receptorin Dallas, the researchers found that the tumor - suppressive activity of geranylgeraniol was accompanied by down - regulation of HMG CoA reductase, a key enzyme in the mevalonate pathway that provides essential intermediates for the posttranslational modification of growth - related proteins such as Ras, nuclear lamins and insulin - like growth factor receptorin the mevalonate pathway that provides essential intermediates for the posttranslational modification of growth - related proteins such as Ras, nuclear lamins and insulin - like growth factor receptors.

We demonstrated the technique on 20 different biological processes spanning four orders of magnitude in space and time, including the binding kinetics of single Sox2 transcription factor molecules, 3D superresolution photoactivated localization microscopy of nuclear lamins, dynamic organelle rearrangements and 3D tracking of microtubule plus ends during mitosis, neutrophil motility in a collagen mesh, and subcellular protein localization and dynamics during embryogenesis in Caenorhabditis elegans and Drosophila melanogaster.

Progeria and lamin A processing in mammalian cells; ubiquitin - proteasome mediated protein quality control in yeast.

Nuclear titin interacts with A-and B - type lamins in vitro and in vivo.

Using mutated versions of the lamin A gene as an example to demonstrate the versatility of their virus - based approach, researchers at the Salk Institute for Biological Studies successfully edited a diseased gene in patient - specific induced pluripotent stem cells as well as adult stem cells.

A rare, premature aging disease, Hutchinson - Gilford progeria is caused by a single point mutation in the gene encoding lamin A, which forms a protein scaffold on the inner edge of the nucleus that helps maintain chromatin structure and organize nuclear processes such as RNA and DNA synthesis.

«Lamin A mutations mainly effect mesoderm - derived tissues, thus gene - editing in these cells could be an attractive therapeutic option.»

Director: Patrick Ryder Cast: Leila Kotori, Alex Phillips, Nadia Lamin, Mitch Rouse Plot: In a dystopian future, a lonely girl Continue reading →