Sentences with phrase «in lamina»

Typically, there is an increased number of lymphocytes and plasmocytes in the lamina propria (less frequently in the submucosa and muscularis).

This occurs in the lamina propria and crypt regions of the intestine when the patient eats specific food - grain antigens, or toxic amino acid sequences.

In the lamina cribrosa, like the trabecular meshwork we hypothesize that exosomes participate in the turnover of extracellular matrix and homeostatic signaling with cell neighbors, particularly in response to elevations in intraocular pressure / pulsations.

Though the precise mechanism is unclear, it is thought that these changes in the lamina are detrimental to the nerve fibers.

Our proposed experiments simulate the forces experienced by cells in the lamina in two ways.

Significant increases in neuron numbers were not observed in lamina 4, 5, 6 adjacent to injury centers, despite rescue of neurons more distal to the zone of injury; an outcome most likely due to neuron loss resulting from direct trauma to these laminae at time of injury.

b - d) Representative high - magnification confocal micrographs depicting co-localization between pab27576 (red) and b) McSA1 (green) binding sites, c) MOAB - 2 (green) and d) Nu1 (green) in lamina V neurons of the parietal cortex, at the pre-plaque stage (3 month - old transgenic rats).

We hope to determine if proteins present in lamina cribrosa of glaucoma patients differ to those found in people who do not have the disease; as these proteins may contribute to disease progression.

But it seems a lot more worrying to me in that Lamina is not the answer to the two big problems facing the boss in his squad options.

In contrast, although SCI rats that were treated with hGPCs and hGDAsCNTF showed positive trends in neuron protection for laminae 8 and 9, this did not translate to improvements in grid - walk performance and these cells failed to promote statistically significant increases in neuronal survival even in laminae into which they had migrated.

hGDAsBMP were able to promote survival of multiple neuronal populations within multiple gray matter laminae with notably robust increases of up to 69 % in neuronal survival in laminae 8 and 9 containing motor neurons.

Transplantation of hGDAsBMP (C) promotes significant protection of neurons in laminae 7, 8, and 9 at the injury center.

At 5 weeks post injury / transplantation, NeuN + neuron cell bodies were counted in laminae 4 to 9 on the injured, right hand side of the spinal cord (Tables 1 and 2).

Graphs show percentage changes in numbers of NeuN + neurons in laminae 4 to 9; laminae 4, 5, and 6; 7; and 8 and 9 in spinal cords from animals that received transplants of 9W2 or 9W1 hGDAsBMP, hGDAsCNTF or hGPCs and untreated control injuries.

Not exact matches

When, in the universe in movement to which we have just awakened, we look at the temporal and spatial series diverging and amplifying themselves around and behind us like the laminae of a cone, we are perhaps engaging in pure science.

The sorting machine sorts whole leaf tobacco prior to threshing, but has proven itself also in sorting oriental, Rajangan and even lamina type of tobaccos.

Lyon did have a golden opportunity to score in the first half when Lacazette missed a penalty and the Ligue 1 outfit were unable to capitalise following Lamina being sent off for Juve.

In count three, Lamina was accused of forcefully taking over and remaining in possession of 200 plots of land in Mowo Kekere belonging to Planet Properties Ltd contrary to Section 2 (2) of the same law, while in count five, the defendants were said to have fraudulently sold 60 hectares of land which had been previously sold by the rightful owner contrary to Section 8 (1)(b) of the laIn count three, Lamina was accused of forcefully taking over and remaining in possession of 200 plots of land in Mowo Kekere belonging to Planet Properties Ltd contrary to Section 2 (2) of the same law, while in count five, the defendants were said to have fraudulently sold 60 hectares of land which had been previously sold by the rightful owner contrary to Section 8 (1)(b) of the lain possession of 200 plots of land in Mowo Kekere belonging to Planet Properties Ltd contrary to Section 2 (2) of the same law, while in count five, the defendants were said to have fraudulently sold 60 hectares of land which had been previously sold by the rightful owner contrary to Section 8 (1)(b) of the lain Mowo Kekere belonging to Planet Properties Ltd contrary to Section 2 (2) of the same law, while in count five, the defendants were said to have fraudulently sold 60 hectares of land which had been previously sold by the rightful owner contrary to Section 8 (1)(b) of the lain count five, the defendants were said to have fraudulently sold 60 hectares of land which had been previously sold by the rightful owner contrary to Section 8 (1)(b) of the law.

The scientists measured how much the soil animals ate using «bait lamina strips»: small sticks with holes in which the researchers filled substrate that resembled the organic matter in the soil.

At the same time, coauthor Peter Adams, from the University of Glasgow, published a previous study on the breakdown of the nuclear lamina in which he observed a peculiar protrusion, or blebbing, of the nuclear envelope into the cytoplasm, and these blebs contained DNA, nuclear lamina proteins, and chromatin (the nuclear structures in which genes reside).

In support of this notion, the team found that in late middle - aged normal cells, blocking the autophagy - driven breakdown of the nuclear lamina can make cells live 60 percent longeIn support of this notion, the team found that in late middle - aged normal cells, blocking the autophagy - driven breakdown of the nuclear lamina can make cells live 60 percent longein late middle - aged normal cells, blocking the autophagy - driven breakdown of the nuclear lamina can make cells live 60 percent longer.

Using sophisticated biochemical and sequencing methods, Dou found that laminB1, a key component of the nuclear lamina, and LC3 were contacting each other in same places on chromatin.

«We found that the molecular machinery of autophagy guides the degradation of components of the nuclear lamina in mammals,» said senior author Shelley Berger, PhD, the Daniel S. Och University Professor in the departments of Cell & Developmental Biology, Genetics, and Biology.

We selectively ablated lamina I neurons expressing GRPR in the spinal cord of mice.

Here, we show that in germ - free (GF) mice, invariant natural killer T (iNKT) cells accumulate in the colonic lamina propria and lung, resulting in increased morbidity in models of IBD and allergic asthma as compared with that of specific pathogen - free mice.

The structure shows that the genome is arranged such that the most active genetic regions are on the interior and separated in space from the less active regions that associate with the nuclear lamina.

These cells are localized in the gut lamina propria and require the presence of B cells in the same location both in humans and in mice.

In the absence of dystrophin, the polarity effector Par1b is dysregulated, leading to the failure of Par3 to become localized to the cortex associated with the basal lamina.

Improving our understanding of the relationship between changes in the retinal microvasculature, RNFL and lamina cribrosa in the pathophysiology of glaucoma can inform the development of new therapeutic targets designed to slow the microvasculature changes as a new non-IOP lowering approach to glaucoma therapy.

Roles of the Nuclear Lamina in Stable Nuclear Association and Assembly of a Herpesviral Transactivator Complex on Viral Immediate - Early Genes.

It is characterized by thin laminae breaking with an irregular curving fracture parallel to in situ bedding planes.

a-b) Representative high - magnification confocal micrographs depicting co-localization between pab27576 (red) and MOAB - 2 (green) in CA1 neurons of the hippocampus a) and neurons of lamina V of the parietal cortex b) at post-plaque stages (13 months).

Representative high - magnification confocal micrographs depicting lack of complete co-localization between pab27576 (red) and McSA1 (green) immunoreactive sites at 3 months and 13 months in CA1 neurons of the hippocampus, and neurons of lamina V and III of the parietal cortex.

While future studies will reveal whether transplantation of hGDAsBMP to DLF injuries provide protection of red nucleus neurons, hGDAsBMP provided robust neuron protection in multiple spinal cord laminae, even in more distant gray matter in which there was no evidence of hGDAsBMP migration.

Montaged images of NeuN immuno - histochemistry at the C5 spinal level of normal (A) and untreated injured (control) spinal cords (B) show that the unilateral DLF transection injury causes loss of NeuN + neurons in multiple spinal cord laminae adjacent to the transected white matter.

Here we show that T cells that express the canonical hValpha7.2 - Jalpha33 or mValpha19 - Jalpha33 TCR rearrangement are preferentially located in the gut lamina propria of humans and mice, respectively, and are therefore genuine mucosal - associated invariant T (MAIT) cells.

(B) Analysis of neuron survival within laminae immediately adjacent to the site of injury shows that hGDABMP transplantation promoted significant protection of neurons when all laminae were considered (4 to 9), with the most robust increases in neuron numbers in intermediate (7) and ventral (8 and 9) gray matter laminae.

Analysis of a region closer to the site of injury, through 750 µm of tissue spanning the injury center, revealed notably robust increases in numbers of neurons for lamina 7 (35 % and 32 %) and laminae 8 and 9 (70 % and 54 %) above control injured cords (Fig. 7 B; Table 2).

In the first few years we successfully reconstructed an array of lamina cartridges and a medulla column using a newly developed automated reconstruction pipeline for transmission electron microscopy (TEM) images.

W. Daniel Stamer, PhD Duke University Eye Center, Durham, NC Funded by The Alcon Foundation Project: Role of Exosomes in Glaucomatous Lamina Cribrosa Remodeling

In the present study we mimicked pressure pulsations by cyclically stretching lamina cribrosa cells and collecting / purifying released exosomes from the cell culture media.

The analysis in the G93A mice showed that lithium delayed cell death within lamina IX and cranial MN while it increased the number of lamina VII Renshaw - like neurons above control values.

In the thoracic region the lumbodorsal fascia is a thin fibrous lamina which serves to bind down the Extensor muscles of the vertebral column and to separate them from the muscles connecting the vertebral column to the upper extremity.

INFLAMMATORY BOWEL DISEASE (IBD) The inflammatory bowel diseases (IBD) are the most common causes of chronic vomiting and diarrhea in dogs, and refer to a group of idiopathic, chronic gastrointestinal tract disorders, characterized by infiltration of the lamina propria by lymphocytes, plasma cells, eosinophils, macrophages, neutrophils, or combinations of these cells.12 The diagnosis of IBD requires the comprehensive exclusion of potential causes of gastrointestinal inflammation, including intestinal parasites, small intestinal bacterial overgrowth, bacterial enterocolitis, dietary intolerances or allergies, and neoplasia.12 Failure to eliminate known causes of gastrointestinal inflammation which can mimic IBD can result in frustration for the owner and clinician due to poor responsiveness of the animal to dietary or pharmacologic therapy.

Within 4 - 6 days virus multiplication occurs within lymphoid follicles in the spleen, lamina propria of the stomach and small intestine, mesenteric lymph nodes and Kupffer cells.

In the C - terminus, missense mutations in residues ranging from positions 342 to 452 are thought to inhibit the attachment of ColQ to the basal lamina of the muscle cell [30]--[33In the C - terminus, missense mutations in residues ranging from positions 342 to 452 are thought to inhibit the attachment of ColQ to the basal lamina of the muscle cell [30]--[33in residues ranging from positions 342 to 452 are thought to inhibit the attachment of ColQ to the basal lamina of the muscle cell [30]--[33].

The collagen domain assembles the triple helix, while the C - terminal domain is involved in both the formation of the triple helix [30] and anchoring of the structure to the basal lamina [30], [31].

A German Cremaster Fanatic sent me a link to his Tar Art Rat blog, where he has posted a transcript of a Q&A session with Matthew Barney (plus a few video clips) after a screening of De Lama Lamina at the Babylon Theater in Berlin on October 25.

The delay is expected in order to heat ocean water thermo - cline lamina, to liberate CO2 and to transfer it to the atmosphere.

The cracks in EIFS laminas are often found initially at reveals and at window openings.