Not exact matches
The team additionally found that suppressing the M1 receptors with a drug
called dicyclomine exacerbated
learning and memory impairment
in the Alzheimer's mice,
and led to the appearance of more of the plaques
and tangles.
The researchers found that the so -
called mushroom bodies, the lobes that underlie
learning and memory in insects, were larger
in dominant wasps than
in their subordinate peers.
Cory Blaiss, then at the University of Texas Southwestern Medical Center,
and her colleagues genetically engineered mice such that the researchers could selectively turn neurogenesis on or off
in a brain region
called the hippocampus, a ribbon of tissue located under the neocortex that is important for
learning and memory.
They used a somewhat bizarre technique
in which two mice were sutured together
in such as way that they shared a circulatory system (known as parabiosis),
and found old mice joined to their youthful counterparts showed changes
in gene activity
in a brain region
called the hippocampus as well as increased neural connections
and enhanced «synaptic plasticity» — a mechanism believed to underlie
learning and memory in which the strength of neural connections change
in response to experience.
Neurons are born
in two areas: a
memory -
and -
learning center
called the hippocampus
and the subventricular zone, which surrounds the two vacant spaces
in the middle of the brain.
On the surface of our numerous star - shaped brain cells
called astrocytes, they have found the molecule LRP4 is important
in ensuring healthy levels of a brain chemical that enables
learning and memory, said Dr. Lin Mei, chairman of the Department of Neuroscience
and Regenerative Medicine at the Medical College of Georgia at Augusta University
and Georgia Research Alliance Eminent Scholar
in Neuroscience.
APPL is found throughout the fruit - fly brain, but primarily
in the so -
called alpha - beta neurons that are vital to
learning processes
and memory.
What's more, the same mechanisms are likely at play
in one of the most common forms of epilepsy,
called temporal lobe epilepsy (TLE), which targets brain regions responsible for
learning and memory.
Researchers also knew that the composition of the receptor, which is made up of four subunits, is different
in children than
in adults, says Princeton University neurobiologist Joe Tsien;
in children, who generally have better
memories and seem to
learn faster, the receptor contains more of the subunit
called NR2B.
Those key cells are
called GABAergic interneurons
in the hilus of the hippocampus, an area of the brain involved
in learning and memory and affected by Alzheimer's disease.
Using a technique
called parabiosis,
in which the vascular systems of two mice are surgically connected, Villeda's lab had previously discovered that infusing old mice with the blood of younger mice leads to brain rejuvenation, including improvements
in learning and memory, while infusions of old blood cause premature brain aging
in young mice.
Klotho's benefits may be due to its effect on a certain type of neurotransmitter receptor
in the brain,
called NMDA, that is crucially involved
in learning and memory.
The findings revealed that prenatal exposure to a commonly used antiepileptic drug
called valproic acid (VPA) inhibited the birth of new neurons
in the brains of adult mice
and impaired their performance on
learning and memory tasks.
That site is located
in a gene
called HDAC4, known to be critical for
learning and memory in mice.
In both humans
and mice,
learning and memory requires effective communication between brain cells
called neurons.
In fact, numerous animal studies show that soy isoflavones interfere with an enzyme called tyrosine kinase in the hippocampus, a brain region involved with learning and memor
In fact, numerous animal studies show that soy isoflavones interfere with an enzyme
called tyrosine kinase
in the hippocampus, a brain region involved with learning and memor
in the hippocampus, a brain region involved with
learning and memory.
Studies show that nitric oxide signaling
and the blood flow increases it stimulates play a central role
in nerve cell maintenance, growth
and repair.,, Most pertinent to anyone looking to enhance their aptitude for
learning, nitric oxide - induced blood flow also makes forming new
memories physically possible as it plays a key role
in what neurologists
call long - term potentiation, a process required for assembling
and reinforcing new synaptic connections throughout the entire cerebral cortex, striatum,
and hippocampus.
Most pertinent to anyone looking to enhance their aptitude for
learning, nitric oxide - induced blood flow also makes forming new
memories physically possible as it plays a key role
in what neurologists
call long - term potentiation, a process required for assembling
and reinforcing new synaptic connections throughout the entire cerebral cortex, striatum
BDNF helps facilitate neural repair
and enhances
learning and memory.5 Oliff, H. S., Berchtold, N. C., Isackson, P., and Cotman, C. W. «Exercise - induced regulation of brain - derived neurotrophic factor (BDNF)... continue 6Yang, J. L., Lin, Y. T., Chuang, P. C., Bohr, V. A., and Mattson, M. P., «BDNF and Exercise Enhance Neuronal DNA Repair By Stimulating... continue 7Pang, P. T., and Lu, B., «Regulation of Late - Phase LTP and Long - term Memory in Normal and Aging Hippocampus: Role of Secreted Proteins tPA and... continue You could call BDNF «MiracleGro» for the
memory.5 Oliff, H. S., Berchtold, N. C., Isackson, P.,
and Cotman, C. W. «Exercise - induced regulation of brain - derived neurotrophic factor (BDNF)... continue 6Yang, J. L., Lin, Y. T., Chuang, P. C., Bohr, V. A.,
and Mattson, M. P., «BDNF
and Exercise Enhance Neuronal DNA Repair By Stimulating... continue 7Pang, P. T.,
and Lu, B., «Regulation of Late - Phase LTP
and Long - term
Memory in Normal and Aging Hippocampus: Role of Secreted Proteins tPA and... continue You could call BDNF «MiracleGro» for the
Memory in Normal
and Aging Hippocampus: Role of Secreted Proteins tPA
and... continue You could
call BDNF «MiracleGro» for the brain.
Research of adults
in their mid 60s showed that an area of the brain
called the hippocampus, the seat of
learning and memory, grew
in the subjects who walked regularly compared to subjects who did other forms of exercise.
In 1973, Anderson
and Bower developed the model
called «human associative
memory or HAM» wherein
learning is based on
memory of «facts, time, predicate (or subject),
and objects (or relationships)» (Saettler, 2004, p. 327).
So the trick for trainers
and instructional designers: providing instruction
in such a way that
learning in working
memory can be moved to long - term
memory where it will, we hope, be
called upon as needed, possibly
in a not - very - conscious way.