Sentences with phrase «in line editing»

As I mentioned in the Line Editing post, in my experience, line editing is the hardest type of editing to nail down.

In line editing, the editor looks at your book line by line and analyzes each sentence.

In line editing the editor gets involved with the trees, line by line, and I'm not just referring to comma faults and misspelled or misused words.

Yet, as I mentioned in my introduction, we have to be careful about just taking an editor's word for it that their strength lies in line editing.

If the book is complete, I recommend that we start with a developmental edit so that we can address any organizational or content weaknesses before perfecting the language in a line edit.

Not exact matches

Everything in the email goes into Asana, from the subject line to the body text and any attachments — and you can edit text and add your own notes before forwarding.

While many clients will edit lightly, and once in a while someone will take the time to write their own, for the most part, the clients post something much along the lines of what you wanted.

In this edited excerpt, Bly offers smart advice on why and how you should build out your product line.

i actually created my first editorial calendar yesterday (in Excell) for an on - line portal i'm editing — in addition to your template it includes topics / categories as well, but your post and following comments gave me some great ideas to upgrade it.

When Harold Ross launched the New Yorker in 1925, the line was that it is not edited for the little lady in Dubuque.

Societies are actually formed for his cult; a periodical organ exists for its propagation, in which the lines of orthodoxy and heterodoxy are already beginning to be drawn; (I refer to The conservator, edited by Horace Traubel, and pubished monthly at Philadelphia.)

Jay Tufele, arguably Michigan's top remaining target on the defensive line, shared with this «Poly Pipeline» edit that he'll be in...

After every line of spoken dialogue in a two - and - a-half hour movie, edit in an extra five - second pause between the next line of dialogue, and see how the three - hour movie feels.

This line was added in the editing process and does not reflect the views of the author.

He personally edited out another line, although it was included in the prepared remarks provided to reporters, that there is «nothing to be proud of in being a dysfunctional homosexual.»

UPDATE: The first line of this post has been edited to reflect the fact that there are, in fact, two women in the running for this seat, as referenced by the sentence above.

Stefanik crossed party lines back in 2015 to vote in favor of the TPA (edited, see below), putting her on the same side of the issue as President Obama, who now finds himself at odds with the woman who is seeking to replace him, presumptive Democratic presidential nominee Hillary Clinton.

@Carpetsmoker: I edited my question to make it more clear that I'm talking about the effected of changes in district lines since 2008.

In the course of that editing, we may need to fudge the time line — both in anticipation of an event and after the facIn the course of that editing, we may need to fudge the time line — both in anticipation of an event and after the facin anticipation of an event and after the fact.

Gene editing could include altering genes in one person — say to treat leukemia in one patient or make a cosmetic change — but, more controversially, it could also include making changes to the germ line that would then alter the genome for an individual's children, grandchildren and the following generations, with potentially unknown repercussions.

For his part, Eric Lander from the Broad Institute said in a December 1 presentation at the summit that the need to employ germ line editing would remain very, very rare thanks to other already available reproductive technologies like in - vitro fertilization that could help most people.

In line with the views of most biomedical researchers, lawmakers struck a note of caution about the implications of new gene editing techniques that make heritable changes to human embryos.

But in September last year the team announced it had applied to conduct genome editing on these embryos — five months after researchers in China had reported experiments applying CRISPR — Cas9 genome editing to non-viable human embryos, which sparked a debate about how or whether to draw the line on gene - editing in human embryos.

If RNA editing allows changes in the cephalopod's DNA to occur at a markedly slower rate than is normally assumed, the animals most likely arose many millions of years earlier than current time lines suggest.

These techniques will also allow scientists to use the CRISPR - Cas9 gene editing system to track changes in germ line.

«There's an important and clear ethical boundary between genome editing in somatic cells versus in the germ line.»

Regulatory debate Huang's team's April report spawned a flurry of scientific and policy meetings and statements as governments and policy experts wrestled with how or whether to draw the line on gene editing in human embryos.

We'll have a post that goes into the mouse genome editing process in a bit more detail in the coming weeks, but, in this post, we will outline a simple method for selecting the guide RNA, validating its efficacy in vitro, and using it in mouse embryos to generate gene modified mouse lines.

Investigating mouse models for biological for research The congress aims to promote the International Mouse Phenotyping Consortium (IMPC) mouse lines, importance of mouse phenotyping & clinical and drug discovery collaboration, to present progresses performed by IMPC with regards CRISPR editing genome, rare diseases, microbiota and ageing pipeline, as well as illustration of examples of scientific projects about «Animal models for human diseases» and recent developments in mouse models phenotyping imaging.

These include in vitro editing of primordial germ cells that are subsequently transmitted through germ - line chimeras to produce genome edited offspring, and direct injections to developing embryos, creating germ - line chimeras in ovo (in the egg), which can then be bred to produce genome edited offspring.

The most radical news at the conference was the first reported use of CRISPR / Cas9 to generate precise genome edits (changing only a single base pair) in two genes, not only in cell lines in vitro, but also in specific tissues of embryos in ovo.

Later, this edited clonal cell line can be differentiated into a cell type relevant to the disease under study (e.g., neurons, as depicted in Figure 1).

Cellartis human iPS cells from the ChiPSC22 line (Figure 2) and the ChiPSC18 line (Figures 3 — 7 and Table I) were grown in the Cellartis DEF ‑ CS 500 Culture System before editing.

Single - cell seeding of edited hiPS cells in this system results in high survival of pluripotent, edited clones, yielding a diverse set of edited clonal lines.

Pluripotency was maintained in all edited clonal lines, as evidenced by the persistent expression of the three pluripotency markers.

This must be accomplished by using a process known as germ - line transmission, where the primordial germ cells (PGCs) of an early embryo are edited, grown in cultures, and then reproductively transmitted through surrogate host parents to generate live, engineered birds.

In addition to our computational work, we run a small wetlab where we use CRISPR - Cas genome editing in human cell lines to obtain a deeper understanding of how genetic variants affect the celIn addition to our computational work, we run a small wetlab where we use CRISPR - Cas genome editing in human cell lines to obtain a deeper understanding of how genetic variants affect the celin human cell lines to obtain a deeper understanding of how genetic variants affect the cell.

By growing primordial germ cells in culture researchers can make genome edits sequentially without being restricted by the breeding cycle of living birds, and the cultured cells will contribute to the germ line when injected into new embryos.

The congress aims to promote the International Mouse Phenotyping Consortium (IMPC) mouse lines, importance of mouse phenotyping & clinical and drug discovery collaboration, to present progresses performed by IMPC with regards CRISPR editing genome, rare diseases, microbiota and ageing pipeline, as well as illustration of examples of scientific projects about «Animal models for human diseases» and recent developments in mouse models phenotyping imaging.

Overview: In practice you would select the Cas9 line that's «most efficient at editing» to introduce the gRNA, but I just randomly chose one of my stable pools.

Injecting the dorsal aorta allows the allele to be picked up by primordial germ cells circulating in the blood before migrating to the gonads, thereby incorporating genome edits into the germ - line.

To further facilitate genome editing in pigs, we report here establishment of a pig line with Cre - inducible Cas9 expression that allows a variety of ex vivo genome editing in fibroblast cells including single - and multigene modifications, chromosome rearrangements, and efficient in vivo genetic modifications.

Combining this with recent advances in genome editing techniques such as the clustered regularly interspaced short palindromic repeat (CRISPR) system has provided an ability to repair putative causative alleles in patient lines, or introduce disease alleles into a healthy «WT» cell line.

In the meantime, our experience to date suggests that precise genome editing of putative targets in primary cell systems is possible, offering more human disease relevant systems than conventional cell lineIn the meantime, our experience to date suggests that precise genome editing of putative targets in primary cell systems is possible, offering more human disease relevant systems than conventional cell linein primary cell systems is possible, offering more human disease relevant systems than conventional cell lines.

The CRISPR / Cas9 genome - editing technology allows the rapid generation of genetically modified animals as well as controlled genetic modification in cell lines and primary cells.

In a series of stop - and - go legislation over the past few years, North America finally lifted a ban on germ - line editing — a fancy term for editing inheritable genes, permanently altering the passage of DNA from generation to generation.

Marissa Vosper is the co-founder of Negative Underwear, a line of underthings that's minimalist in style, highly edited, and accessibly priced.

Edit: left out the walnuts because I couldn't wait to get them in the oven and forgot to read the last line!

A Color Story has tools to straighten in the post editing process, but I always try to pay attention to horizontal and vertical lines and make sure they are nice and squared.

These editors are editing out things like protruding ribs, hip bones, smearing out dark circles and filling out hair lines to disguise the fact that in general, very skinny does not mean healthy.