Sentences with phrase «in living animal models»

The faster speed means it will be possible for the first time to watch disease progression in living animal models at the molecular level.

The research team then wanted to see whether the same would occur in live animal models.

This effect was also observed in a live animal model, showing that rats injected with ar - tumerone into their brains experienced increases in neural stem cell proliferation and the creation of newly formed healthy brain cells.

Not exact matches

We are to model our lives after Christ, the Son of God, who though he was God's very equal, came to earth, was born in an animal's feeding stall and died on a cross.

What sorts of mental lives do animals have, and how should we understand welfare?By presenting models for understanding animals» moral status and rights, and examining their mental lives and welfare, David DeGrazia explores the implications for how we should treat animals in connection wi...

It is currently playing out in the live animal export sector, where the demise of local processing opened the door for a live export sector, which in turn through its simple business model has compromised livestock welfare and alienated many consumers, reduced employment in Top End towns which once had abattoirs, and added risk to cattle business profitability by providing only one market outlet.

The search for more of these factors is complicated by the rarity of brain samples from suicide victims and the lack of an animal model — humans are unique in their wilful ability to end their lives.

In animal models, the researchers found that using microRNA to disrupt cells in the brain's prefrontal cortex — a region associated with complex planning and decision - making — affected learning and memory later in lifIn animal models, the researchers found that using microRNA to disrupt cells in the brain's prefrontal cortex — a region associated with complex planning and decision - making — affected learning and memory later in lifin the brain's prefrontal cortex — a region associated with complex planning and decision - making — affected learning and memory later in lifin life.

Scientists of the German Center for Diabetes Research (DZD) led by the German Institute of Human Nutrition (DIfE) have shown in a mouse model that the epigenetic * modification of the Igfbp2 ** gene observed in the young animal precedes a fatty liver in the adult animal later in life.

«They are more true - to - life than cells in dishes and more human - like than animal models,» said Hamilton.

To better determine the role of specific chemoattractants in type III hypersensitivity, lead author Yoshishige Miyabe, MD, PhD, a research fellow in Luster's lab, used multiphoton intravital microscopy — an imaging technology pioneered for studies of immune cell movements in living animals by CIID investigator and co-author Thorsten Mempel, MD, PhD — to follow in real time the development of IC - induced arthritis in a mouse model of rheumatoid arthritis.

The research showed that moral decisions in the con?ned scope of unavoidable traffic collisions can be explained well, and modeled, by a single value - of - life for every human, animal, or inanimate object.

Using a novel approach for imaging the movement of immune cells in living animals, researchers from the Massachusetts General Hospital (MGH) Center for Immunology and Inflammatory Diseases (CIID) have identified what appear to be the initial steps leading to joint inflammation in a model of inflammatory arthritis.

One of the major next steps would be placing the engineered tissue in the vocal cords of living animal models and having it survive and work.

Since olfactory sensory neurons regenerate throughout life, even in humans, the investigators were able to measure neuron regeneration in specific animal models.

The use of cell surface markers to isolate specific cell populations is one common method for separating cells; however, isolating live cells based on their RNA expression is a powerful new way enabling the study of small cell niches in nongenetically modified animal models and human tissue.

Some theoretical models suggested that new neurons destabilize memories already stored in the hippocampus by degrading the information there, but the idea had never been explored in live animals.

«I did a lot of modelling to work out how far we needed to move the mine before detonating it — for the protection of both the pipeline and the animals that we know live in that area.»

Historically, animal models — from fruit flies to mice — have been the go - to technique to study the biological consequences of aging, especially in tissues that can't be easily sampled from living humans, like the brain.

Artifacts from that period — the obese human and animal figurines and the phallic symbols carved in stone or bone and modeled in clay — point to the idea that the people had an obsession with the living world and its successful propagation through the descent group or lineage.

But in living choanoflagellates, King believes researchers have a model organism to compare with animals and dissect the roots of animal multicellularity.

In a study published in the June 12 edition of Science, they detail how a new drug repaired damage to the colon, liver and bone marrow in animal models — even going so far as to save the lives of mice who otherwise would have died in a bone marrow transplantation modeIn a study published in the June 12 edition of Science, they detail how a new drug repaired damage to the colon, liver and bone marrow in animal models — even going so far as to save the lives of mice who otherwise would have died in a bone marrow transplantation modein the June 12 edition of Science, they detail how a new drug repaired damage to the colon, liver and bone marrow in animal models — even going so far as to save the lives of mice who otherwise would have died in a bone marrow transplantation modein animal models — even going so far as to save the lives of mice who otherwise would have died in a bone marrow transplantation modein a bone marrow transplantation model.

The first genetic clues for slowing aging emerged from animal models in which the effect of individual genes on average life spans could be tested.

Also, research in other animal models, such as rodents, has shown anesthesia exposure early in life can lead to cell death in the brain and cognitive impairments.

You can also learn about the real - world plant and animal life that inspired Avatar's fictional flora and fauna, peer inside the Armored Mobility Platform suit that was used in combat scenes, and examine the filmmakers» models of Na» vi characters and their costumes.

In order to understand the biology of fossilized animals, researchers often turn to living animals with similarities that help model how extinct animals moved.

Using a mouse model of fragile X syndrome, the researchers recorded the activity of networks of neurons in a living mouse brain while the animal was both awake and asleep.

And a variety of studies with animal models has shown that nanoparticles can trigger damage in living tissues (Science, 18 June 2004, p. 1732).

«We wanted to develop a newborn screen for NPC because we know that the earlier we intervene with investigational treatments in animal models of the disease, the longer the animals live,» said Ory, the Alan A. and Edith L. Wolff Distinguished Professor of Medicine.

The team, including researchers from the Natural History Museum in London, quantified the anatomical and genetic differences between living animals, and established a timeframe over which those differences accumulated with the help of the fossil record and intricate mathematical models.

Instead of using whole animals, these models used cells taken from live animals and grown in Petri dishes.

Rieger used zebrafish larvae to model peripheral neuropathy because the embryos develop rapidly and because the larval fish are translucent, making them ideal for studying the progression of nerve degeneration in live animals.

Kissler and his research team are using a mouse model of type 1 diabetes to see what the genes do in a living animal.

Current in vitro hematopoiesis models fail to demonstrate the cellular diversity and complex functions of living bone marrow; hence, most translational studies relevant to the hematologic system are conducted in live animals.

Taking advantage of fly genetics The research will combine the strength of the fly system (animals that are short lived but complex enough to model regenerative activity in vertebrates) with genetic studies in mice to understand the role of mTOR signaling in maintaining the health of adult stem cells in both species.

Microscopic models — half living, half not — may prove more reliable than animals in explaining human disease and testing therapies.

«The pRNA particles we constructed to harbor siRNA have a half life of between five and 10 hours in animal models, are non-toxic and produce no immune response,» says Guo [abstract].

This allowed for them to study infection in a model highly related to humans but without the need to infect a living animal.

After years of experimenting with FMD in animal models and showing its benefits on metabolism and life span, Dr. Longo's team analyzed the effects in a human clinical trial that was published earlier this year.

In a study which takes us back to the previously described work of Fenton Turck in 1916 [91, 92], a French group have recently reported that after one week of a high - fat diet, prior to full onset type 2 diabetes (or the animal model thereof), live commensal bacteria are found in the blood and adipose tissue where they are associated with low - grade inflammation [93In a study which takes us back to the previously described work of Fenton Turck in 1916 [91, 92], a French group have recently reported that after one week of a high - fat diet, prior to full onset type 2 diabetes (or the animal model thereof), live commensal bacteria are found in the blood and adipose tissue where they are associated with low - grade inflammation [93in 1916 [91, 92], a French group have recently reported that after one week of a high - fat diet, prior to full onset type 2 diabetes (or the animal model thereof), live commensal bacteria are found in the blood and adipose tissue where they are associated with low - grade inflammation [93in the blood and adipose tissue where they are associated with low - grade inflammation [93].

Spermidine both increases lifespan and healthspan in animal models, and is enriched in the blood of humans living past 90.

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«The dog and cat industry has long served as a model of how to provide support for animals throughout all stages and challenges of life,» says Lucas Stock, communications manager at Oxbow Animal Health based in Omaha, Neb. «Knowledge and education regarding the longevity and specific health needs of small animals has evolved considerably in recent decades and across all sectors.»

Ultimately, it is up to parents or other significant role models in a child's life to guide them in the discovery of what is a proper pet, how to handle, care and feed pets as well as the commitment made to an animal we take into our custody... that it's for the life of the pet....

HART's Animal Adoption Center has become a model for compassionate animal rescue and community involvement in saving the lives of companion anAnimal Adoption Center has become a model for compassionate animal rescue and community involvement in saving the lives of companion ananimal rescue and community involvement in saving the lives of companion animals.

We've invested our resources in building community collaborations where animal welfare organizations come together to develop successful models of lifesaving; in veterinary colleges to help shelter medicine become part of the veterinary curriculum to train veterinarians to save the lives of sick and injured dogs and cats in animal shelters; and in the implementation of a national strategy to promote accountability and transparency in animal shelter operations.

To achieve this goal, Maddie's Fund is investing its resources in building community collaborations where animal welfare organizations come together to develop successful models of lifesaving; in veterinary colleges to help shelter medicine become part of the veterinary curriculum to train veterinarians to save the lives of sick and injured dogs and cats in animal shelters; and in the implementation of a national effort to promote accountability and transparency in animal shelter operations.

He was sickened by the revelation of the lives animals lead in mills, and shifted his business model to adoption, pet supplies and services.

The animal shelters chosen for our Future Five: Shelter Partners to Save Cats» Lives program have already made significant progress in their journeys to become model shelters.

Originally created in 2017 by the Petco Foundation and Jackson Galaxy Foundation, it is modeled after the critically - acclaimed tv - show Shark Tank, but with one major difference — The Innovation Showdown's ultimate goal is not a financial return on investment but a lifesaving return on investment — that is to save the lives of more animals in need.