Sentences with phrase «in lung fibroblasts»

Forkhead Box F1 represses cell growth and inhibits COL1 and ARPC2 expression in lung fibroblasts in vitro.

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FGFR inhibitors are a new family of targeted agents designed to inhibit the action of the fibroblast growth factor receptor, which is often overexpressed in lung, bladder, biliary and breast cancers.
The experiments, including studies conducted in a bioengineered 3 - D model of lung tissue seeded with relevant cells, showed that CHI3L1 regulates a pathway that recruits cells such as macrophages and fibroblasts that produce the scarring, or fibrosis.
This experiment uses quantitative PCR to detect the expression level of POSTN in CD34 + / CD31 − pulmonary fibroblasts, CD31 + endothelial cells, and CD45 + immune cells isolated from lungs of mice with macrometastases, which is a replication of the experiment reported in Figure 2H.
Function, activity, and membrane targeting of cytosolic phospholipase A2ζ in mouse lung fibroblasts.
Lung fibroblasts accelerate wound closure in human alveolar epithelial cells through hepatocyte growth factor / c - Met signaling.
«Fibroblasts are also abundant and integrally involved in many other tissues, including skin, breast, lung and some cancers.
Normal human lung fibroblasts (NHLF) cells grown in 384 - well Optilux plates were treated with candidate compounds and incubated for 18 hours prior to fixation and staining with Hoescht dye and anti-HMOX1 antibody as described in Materials and Methods.
A recent report demonstrated a significant increase in COX2 expression in normal lung fibroblasts when exposed to cigarette smoke extracts [46].
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