Certain particle compounds may directly generate ROS in vivo because of their surface chemistry (eg, metals, organic compounds, and semiquinones) or after bioactivation by cytochrome P450 systems (eg, polycyclic aromatic hydrocarbon conversion to quinones).6, 290 a, 290 b A particle surface or anions present on otherwise more inert particles may disrupt iron homeostasis in the lung and thereby also generate ROS via Fenton reactions.291 Other PM constituents may do so indirectly by the upregulation of endogenous cellular sources (eg, nicotinamide adenine dinucleotide phosphate [NADPH]-RRB- oxidase) 292,293 or by perturbing organelle function (eg, mitochondria) by taken - up PM components.261 Particle stimulation of irritant and afferent ANS fibers may also play a role in local and systemic oxidative stress formation.294 Given the rich antioxidant defenses
in the lung fluid, secondarily generated oxidization products of endogenous molecules (eg, oxidized phospholipids, proteins) or a reduction in endogenous antioxidants per se may be responsible at least in part for the state of oxidative stress in the lungs (along with instigating the subsequent cellular responses) rather than ROS derived directly from PM and its constituents.
Released metal particles from the smoldering pit of the World Trade Center were so fine that they could easily slip past a paper face mask and reach deep into lung tissue, where they are poorly soluble
in lung fluid.
A suspected trigger for this constriction is adenosine, a chemical messenger found in high amounts
in the lung fluid of asthmatics, says Jonathan Nyce, a molecular pharmacologist at EpiGenesis Pharmaceuticals in Greenville, North Carolina.
Not exact matches
The researchers placed extremely premature fetuses into the Biobag, which is made of clear polyethylene and filled with a substance that mimics amniotic
fluid,
in order to help them survive long enough for their
lungs to develop more.
After doctors were unsuccessful
in removing
fluid from her
lungs, FoxNews reports that Murrieta was put on a ventilator.
The loss of tissue
fluids has reached a critical level, the compressed heart is struggling to pump thick, heavy blood into the tissues, and the tortured
lungs make a frantic effort to gasp
in small gulps of air.
From Reuters, «chlorine gas turns to hydrochloric acid
in the
lungs and can kill by burning the
lungs and drowning victims
in the resulting body
fluids.»
In utero, the
lungs are undeveloped, un-inflated and filled with amniotic
fluid.
When cold beverages enter the esophagus, it encounters the warm vaporized
fluid in the
lungs.
Their doctor can listen to their chest to see if there's any chest congestion, they may even want to get an x-ray of the chest to see if there's any
fluid collection
in their
lungs, which may be a sign of pneumonia.
I remember lying on the table at the cardiologist's office when they found
fluid in my heart and around my
lungs.
Your little one «breathes» amniotic
fluid in and out of the
lungs.
If baby gets breast milk
in his
lungs, it's a natural
fluid and doesn't inflame the
lungs, it doesn't irritate the
lungs so that inflammation develops.
These microbes can attack the larynx and
lungs filling them with
fluids and this will result
in a gross cough as the baby makes serious attempts to get the
fluid or mucus out of his
lungs through coughing.
Then you can just slowly let the uterus contract out the baby and give it a little bit of time to extrude any
fluid that the baby might have
in his or her
lungs which will help with breathing afterwards.
Your baby may be delivered slowly to allow time for the chest to be squeezed on the way out, as
in a vaginal birth, to clear the
lungs of
fluid.
The baby is practicing breathing and get
fluid in their
lungs, and they get the hiccups.
In the second trimester, the baby begins to breathe and swallow the
fluid to help their
lungs grow and mature.
Also, the newborn baby may breathe
in the meconium - stained amniotic
fluid, which may irritate the
lungs and cause respiratory problems.
Has started «breathing» amniotic
fluid in through its nose and respiratory tract, giving those
lungs some very early...
There's actually no air
in baby's
lungs yet, just amniotic
fluid.
He enjoys sucking
in and out the amniotic
fluid training his
lungs.
While she was
in the womb, her
lungs were filled with
fluid.
Recently, we had a tragedy here
in Petach Tikve where a woman doctor was giving birth and died
in childbirth due to a complication —
fluid went
in the opposite direction —
lungs
If this doesn't happen, this excess
fluid in the
lungs can make it...
Again, I refused, because there is the small but real risk of having the
fluid enter the
lungs, plus the discomfort involved
in having a tube pushed down his nostril and throat into his stomach.
Amniotic
fluid that appears green or brown often indicates that the growing baby has passed their first bowel movement whilst
in the uterus (meconium), yet, a baby will usually not have their first bowl movement until after they are born.If this happens, and the baby does pass meconium within the fetus, it can get into their
lungs and cause serious breathing problems (known as meconium aspiration syndrome).
«They bleed from their mouth and into their
lungs so they start to drown
in their own
fluids.
«They bleed from their mouth and nose, and into their
lungs, so they start to drown
in their own
fluids.
More ominously, at least six of the victims developed acute respiratory distress syndrome, a condition
in which
fluid builds up
in the
lungs and prevents normal breathing.
One of the telltale signs of opioid overdose is frothy
fluid around the nose and mouth and
fluid in the
lungs, called pulmonary edema.
Scientists also create compounds called «potentiators» to activate the CFTR channels at the cell surface to maintain the proper balance of electrolytes
in fluids, including those found inside
lungs.
The main complication
in ARDS is that
fluid leaks into the
lungs making breathing difficult or impossible — and making it difficult to get oxygen into the blood.
Cardiologists from Musgrove Park Hospital, Taunton, writing
in the Journal of the Royal Society of Medicine, say the condition, which causes an excess collection of watery
fluid in the
lungs, is likely to become more common with the increase
in participation
in endurance sports.
Like a real womb, the artificial one also bathes lambs
in the
fluid needed for proper
lung development.
It is caused when
fluids accumulate
in the
lungs and other organs — compromising circulation to the kidneys and brain — and if not successfully treated can be life threatening.
While HAP typically is a less - severe infection, half of patients have serious complications, including respiratory failure,
fluid in the
lungs, septic shock and kidney failure.
Their symptoms, including chest pain,
fluid in the
lungs, and shortness of breath, resembled those of a classic heart infarction, caused by a clogged blood vessel.
The third, SFTPA2, affects a protein expressed only
in the
fluid that bathes the
lung's epithelial cells.
In patients with this mutation, called G551D, the distorted protein obstructs the flow of salt and fluids through the surface of cells, causing mucus in the lungs to thicken like oatmea
In patients with this mutation, called G551D, the distorted protein obstructs the flow of salt and
fluids through the surface of cells, causing mucus
in the lungs to thicken like oatmea
in the
lungs to thicken like oatmeal.
In patients who already have kidney damage, rehydration therapy can cause pulmonary edema, a buildup of fluid in the lung
In patients who already have kidney damage, rehydration therapy can cause pulmonary edema, a buildup of
fluid in the lung
in the
lungs.
Shapiro and his colleagues put
fluid from smoker's
lungs in the upper half of a plastic container whose two compartments were separated by a membrane.
TRALI occurs when air spaces
in the
lungs become acutely inflamed and filled with
fluid following the administration of blood products.
These mice had significantly higher rates of survival and less
fluid in their
lungs than mice not given the drug.
A
lung - on - a-chip created
in the lab of Shuichi Takayama, professor of biomedical engineering and macromolecular science and engineering at the University of Michigan, for example, uses
fluid mechanics to re-create the crackling stethoscope sounds associated with certain diseases of the
lung.
According to The Ohio State University, over half of all patients who are treated for heart failure end up back
in the hospital within six months, due to
fluid buildup
in their
lungs.
Published March 27
in Scientific Reports, a new study co-led by an NYU School of Medicine pathologist reveals that layers of the body long thought to be dense, connective tissues - below the skin's surface, lining the digestive tract,
lungs and urinary systems, and surrounding arteries, veins, and the fascia between muscles - are instead interconnected,
fluid - filled compartments.
A portable ultrasound can help nephrologists better detect
fluid in the
lungs of patients with end - stage kidney disease, according to...
Its main indications are diagnostic (recurrent or persistent pleural exudates, pleural thickening or mass, diffuse interstitial
lung disease, etc.) and therapeutic (pleurodesis
in case of recurrent and / or persistent pleural
fluid accumulation, recurrent or persistent pneumothorax, empyema, etc.).
Herpel didn't think any of those risks factors applied to him
in 2006, when he became extremely fatigued, felt
fluid gurgling
in his
lungs, and started gasping.