Sentences with phrase «in melanoma research»

Caspar Wistar Professor in Melanoma Research Director, The Wistar Institute Melanoma Research Center Professor, Molecular & Cellular Oncogenesis Program

Caspar Wistar Professor in Melanoma Research Director, The Wistar Institute Melanoma Research Center Professor, Molecular and Cellular Oncogenesis Program

The MELGEN European Training Network (ETN) will create a co-operative environment for research and training in melanoma research, with the ultimate aim of improving precision medicine for patients with the disease.

Published in Melanoma Research Pjanova, D., Engele, L., Randerson - Moor, J. A., Harland, M., Bishop, D. T., Newton Bishop, J. A., Taylor, C., Debniak, T., Lubinski, J., Kleina, R., and Heisele, O. (2007).

SMR contributes to advances in melanoma research by catalyzing collaborations among basic, translational, and clinical researchers, carrying new technology - based discoveries from bench to bedside and back.

«Our findings provide a possible flanking strategy to counteract the ability of melanoma cells to re-wire their signaling networks,» said co-coresponding author Meenhard Herlyn, Caspar Wistar Professor in Melanoma Research and director of the Melanoma Research Center at The Wistar Institute.

Not exact matches

Memorial donations may be made in honour of Shawn Price to the Cancer Center of Melanoma Research at CPMC Sutter Health Foundation: www.cpmc.org/giving.

Master of Science candidate in Biomedical Sciences at Mississippi College, Bilal Qizilbash, summarizes his research breakthrough in a nutshell: Juiced curly kale kills melanoma...

I would add that it is of utmost importance to prevent sunburns in kids, as the research shows that the risk of melanoma is greatly increased when kids between 0 and 10 get sunburns.

The annual «This Run's for JACK» 5K Run / Walk to benefit the Jack H. Marston II Melanoma Research Fund will begin at 8 a.m. Sunday at Ackerman Park, at the St. Charles and Riford Roads in Glen Ellyn.

For Molly Schumer, a postdoctoral fellow in genetics and evolutionary biology at Harvard Medical School, the fellowship will help fund her research on how evolutionary forces affect our genes, focusing in particular on a persistent trait that can cause melanoma in swordtail fish.

Horizon has partnered with The Wistar Institute of Anatomy and Biology in Philadelphia, Pennsylvania, to make available their large collection of highly characterized Melanoma PDX models to the research community; these models are representative of all previously well - described melanoma subtypes identified by The Cancer GenomMelanoma PDX models to the research community; these models are representative of all previously well - described melanoma subtypes identified by The Cancer Genommelanoma subtypes identified by The Cancer Genome Atlas.

They published their findings February 6, 2017, in Pigment Cell and Melanoma Research.

They are following up on some of the parallel pathways downstream of PAK to determine how they operate, and are also pursuing research into immunotherapy approaches in melanoma treatment.

A type of soil - dwelling bacterium produces molecules that induce death in melanoma cells, research at Oregon State University shows.

Survivors of melanoma were more likely to limit exposure to the sun than people who had never had the disease, but some still reported seeking out suntans and getting sunburns, reports a new article in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research by Rachel Isaksson Vogel, PhD, an assistant professor in the Department of Obstetrics, Gynecology and Women's Health at the University of Minnesota.

Ms Alice Koechlin, from the International Prevention Research Institute in Lyon, France, told the meeting that people who were at highest risk of dying from melanoma were those born between 1900 and 1960 when not only were the dangerous effects of exposure to ultraviolet (UV) radiation from sunlight largely unknown, but also health professionals believed that sunshine was positively beneficial.

Martin's colleague Catherine Suter of the Victor Chang Cardiac Research Institute in Sydney is studying whether melanoma patients have epimutations in genes associated with the cancer.

Research teams focused on both cutaneous and uveal melanoma are fast - tracking discoveries into the clinical setting, and bringing novel therapeutic options to patients in the Philadelphia region,» said Karen Knudsen, Director of the Sidney Kimmel Cancer Center.

The work published in Cancer Cell complements previous research efforts from the CNIO Melanoma Group, which could lead to the development of novel drugs that selectively target the mechanism of cell autodigestion as a potential therapeutic strategy.

The new research, which studied the immortalization process using genome - engineered cells in culture and also tracked skin cells as they progressed from a mole into a malignant melanoma, suggests that telomerase plays a more complex role in cancer.

A drug approved by the Food and Drug Administration (FDA) for melanoma in combination with a common cholesterol - lowering drug may show promise in controlling cancer growth in patients with non-small cell lung cancer (NSCLC), according to new research from the Icahn School of Medicine at Mount Sinai.

In the April 25 issue of Cancer Cell, a research team, led by Xin Lu, PhD, Ludwig director and member at the University of Oxford and a team of scientists from both institutions, describes how p53 is silenced in advanced melanomas by a protein named iASPP, and applies that information to restore p53 function in such cellIn the April 25 issue of Cancer Cell, a research team, led by Xin Lu, PhD, Ludwig director and member at the University of Oxford and a team of scientists from both institutions, describes how p53 is silenced in advanced melanomas by a protein named iASPP, and applies that information to restore p53 function in such cellin advanced melanomas by a protein named iASPP, and applies that information to restore p53 function in such cellin such cells.

«While more research is needed, this study shows that patients in the study had markers of poor prognosis for their melanoma.

Research from Rutgers Cancer Institute of New Jersey shows that the RUNX2 protein, which regulates the transcription of genetic messages responsible for the different functions of cells, may play a role in melanoma cell growth and spread and could serve as a therapeutic target for the disease.

The research team analyzed BRAF inhibitor resistance in melanoma cell lines, mice bearing human melanoma tumors, and in human tumor biopsy samples.

Application of sun protection factor 30 (SPF30) sunscreen prior to exposure to ultraviolet - B (UVB) light delayed melanoma onset in a mouse model of the disease, according to data from a team at The Ohio State University Comprehensive Cancer Center Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

Dr Wells» team has previously published research on the importance of PAK4 in other types of cancer, including prostate, breast and melanoma.

In the past decade, medical research has discovered direct links between tanning bed use and higher rates of the skin cancers basal cell carcinoma, squamous cell carcinoma and melanoma.

In the past decade, medical research has discovered direct links between tanning bed use and higher rates of the skin cancers basal cell carcinoma, squamous cell carcinoma and melanoma, according to Dr. Thomas.

Unlike other solid tumors, there has been limited progress in understanding the contribution of genetic risk factors to the development of uveal melanoma, researchers say, primarily due to the absence of comprehensive genetic data from patients as the large sample cohorts for this rare cancer type have not been available for research.

Researchers expect the data presented in this study to fuel the formation of large national and international research consortiums to conduct comprehensive, systematic analysis of inherited (germline) genome data in large cohorts of uveal melanoma patients.

That is why «early diagnosis is the best tool we have to date for saving patients.In fact, patients with early - stage melanoma have a survival rate of 95 %, while5 - year survival falls to 50 % in patients with metastasis,» explained Yoana Arroyo, researcher in the UPV / EHU's department of Cell Biology and Histology, where this research was carried out.

«This is a very important discovery that will guide future research efforts to explore the interactions of these pigmentary genes with other genetic and environmental risk factors in cancers not linked to sun exposure, such as eye melanoma.

Joining forces with dermatologists and oncologists from the University Hospital in Zurich and backed by the University Research Priority Program «Translational Cancer Research,» Sommer's team was able to demonstrate that, in melanoma cells, the epigenetic factor EZH2 controls genes that govern tumor growth as well as genes that are important for the formation of metastases.

«Federal funding will be crucial to support research of rare cancers such as eye melanoma as it is likely, as shown in this study, that the impact of such research will extend across the different cancer types,» adds Abdel - Rahman.

Moreover, many people don't apply the proper amount of sunscreen, forget to reapply and missed to apply on all exposed areas resulting in sunburn and increased risk of melanoma,» said Reza Ghiasvand, a PhD candidate at The Department of Biostatistics and a member of the research group «Epidemiological Studies of Lifestyle and Chronic Diseases.»

The team expected to find obesity to be harmful for melanoma patients, based in part on research that implicates obesity in activation of a cancer - promoting molecular pathway called IGF - 1 / PI3K / AKT.

Keiran S. Smalley, Ph.D., scientific director of the Melanoma Research Center of Excellence, and his team began investigating this pathway in 2010 and discovered the best way to block its ability to promote cancer cell growth was with combined inhibitor therapy.

Fresh research at Sahlgrenska Academy has found that antioxidants can double the rate of melanoma metastasis in mice.

The research behind the melanoma finding and Martensen's ALK test began in the 1970s, when a young oncologist named Dennis Slamon became obsessed with the genetics of breast cancer.

The second report, identifies the immunotherapy resistance mechanism in melanoma cells, is from a group led by Kai Wucherpfennig, MD, PhD, director of Dana - Farber's Center for Cancer Immunotherapy Research, and Shirley Liu, PhD, of Dana - Farber.

«The idea is to use a less severe disease as a weapon against malignant melanoma,» says Dr. Jasper van den Boorn from the Institute of Clinical Chemistry and Clinical Pharmacology of the University of Bonn, who previously researched this connection in his doctoral thesis at the University of Amsterdam and demonstrated the fundamental feasibility of this option.

Prof. Marine and his research team also identified a pharmacological way of restoring the expression of FES in human melanoma.

Many of these genes are usually switched off in adults, but previous research has shown that in many cancers — including prostate, ovarian, and brain cancer, melanoma, and leukemia — HOX genes are switched back on, helping the cancer cells to proliferate and survive.

«We need to confirm this synergistic activity of vemurafenib and cediranib across a broader range of melanoma models, investigate why the particular combination is effective, and find biomarkers that predict which patients with BRAF - mutant melanoma should receive this combination,» says Friedman, who is a research fellow in Dermatology at Harvard Medical School.

Melanoma cells become drug resistant by using surrounding healthy cells to provide a «safe haven» from treatment, according to new research published in Cancer Cell.

With enthusiasm for cancer immunotherapy mounting thanks to recent successes in the clinic with immune - based cancer treatments such as anti-CTLA-4 and anti-PD-1 antibodies, and the FDA approvals of sipuleucel - T prostate cancer vaccine and ipilimumab for the treatment of melanoma, and in light of the many promising immunotherapies now in clinical trials with potential for near - term FDA approval, the Cancer Research Institute launched the first annual Cancer Immunotherapy Awareness Month in June 2013 as a way to increase public awareness of the power of immunotherapy to revolutionize cancer treatment and of the need for continued public support for research to bring these treatments to more patientsResearch Institute launched the first annual Cancer Immunotherapy Awareness Month in June 2013 as a way to increase public awareness of the power of immunotherapy to revolutionize cancer treatment and of the need for continued public support for research to bring these treatments to more patientsresearch to bring these treatments to more patients sooner.

Using droplet digital polymerase chain reaction, Rebecca J. Lee, of Cancer Research UK Manchester Institute, and colleagues detected for BRAF and NRAS mutations in plasma taken from 161 patients with high - risk stage II / III melanoma after surgery.

Further research uncovered a broad spectrum of cell surface stem cell markers (e.g., CD133, CD44, and CD24) that allow the identification of CSCs in human solid tumors, including brain, breast, prostate, pancreas, liver, ovary, skin, colon cancers, and melanoma (3 - 6)(Figure 1 based on 7).