Sentences with phrase «in mice and humans»

Depending on results from further behavioural studies in mice and humans, the abnormalities could then be treated in parallel with seizures.

Other studies are looking at its role in improving cognitive function in mice and humans.

The Core provides equipment and services to determine gene expression patterns in mouse and human tissues.

He thinks the hormone might also boost fertility in men, as many hormones have been found to have the same effects in mice and humans.

They found a similar result in depressed mice, suggesting that depression leaves similar footprints in mice and humans.

The team further tested the probe in mice and human serum and report that it performed as expected.

Findings made in animal models do not always translate to patients, but it appears that this important eye vessel functions very similarly in mice and humans.

Our work will investigate these questions in mice and humans and build computer models to test different theories.

Another study found similar results in mice and humans.

Studies in mice and humans have shown that an increase of brown fat in the body is associated with increased resistance to obesity and its related diseases, including diabetes and cardiovascular disease.

Further research will be necessary to establish solid connections between the suPAR production site in mice and the human cell types, Reiser says.

Applicants with interests in mouse and human stem cell models for Alzheimer's and related diseases are particularly encouraged to apply.

In a study in Proceedings of the National Academy of Sciences, Dr. Snyder and his colleagues compared gene expression in 15 different tissue types in mice and humans.

Other groups had discovered hemangioblasts in mouse and human embryonic cells as well as in adult human bone marrow and umbilical cord blood.

«Epigenetic changes promote development of fatty liver in mouse and human.»

In experiments in mice and human cells, researchers found that blocking CXCR4 — a so - called homing receptor protein molecule that helps T cells mature and attracts blood cells to the bone marrow — halted disease progression in bone marrow and spleen tissue within two weeks.

Ultimately, by speeding up and automating the process of mapping such networks in both mouse and human brain tissue, researchers hope to learn how the brain's structure enables us to sense, remember, think, and feel.

So far, both drugs have successfully treated infections in mice and human trials are planned for teixobactin in about two years» time.

Loss of the RING domain predicted poor treatment responses in both mouse and human mammary tumors.

Our mechanistic studies, in both mouse and human mammary cancer cells, indicate that leptin and LepR are necessary for NANOG expression.

The Paigen lab is one of several groups that recently discovered one such gene, Prdm9, which controls the position of recombination sites in mice and humans.

At an earlier stage, Julie Andersen, PhD and coworkers at the Buck Institute have reported that destroying senescent inflammatory cells in the brains of animals substantially protects them against paraquat, a toxin that causes a PD - like syndrome in mice and humans alike by selectively killing dopamine - producing neurons in the brain.

Harmonising ontological descriptions of phenotype in mouse and human and improving links between mouse model data and human data, using diabetes and obesity as examples, will increase the relevance of data that is generated in mouse studies for clinical studies.

Researchers at Gladstone Institutes in San Francisco report that a gene variant associated with Alzheimer's works differently in mice and humans, and they also demonstrate how modifying this gene could potentially prevent the plaques associated with Alzheimer's from forming and damaging the brain.

To translate our in vitro studies in mouse and human ILC3s to an intact organism, we examined if lethal toxin modulated ILC3 function in mice.

One gene, which codes for a powerful growth - stimulating hormone in mice and humans, is expressed only by paternally derived genes.

When administered in restricted amounts, which do not exceed the individual's total energy needs, the KD can also be therapeutic against malignant brain tumors in mice and humans.

The 3 research projects, all led by Andrew McMahon, PhD (Keck School of Medicine of the University of Southern California), looked at distinct aspects of kidney development in mice and humans, as well as the different types of cells involved.

Lethal toxin significantly reduced in vitro IL -23-mediated IL - 22 production in mouse and human ILC3s.

«Studies of intermittent fasting that do exist in both mice and human subjects are promising and exciting with regards to beneficial changes in insulin resistance, blood lipids, gene expression, mental clarity and even reproductivity,» she says.

A study published by Cell Press October 16th in Cell now reveals that gut microbes in mice and humans have circadian rhythms that are controlled by the biological clock of the host in which they reside.

The same observations were made in organoids (artificially grown masses of cells that resemble an organ) created from unique basal progenitor cells that were isolated from the gastroesophageal junction in mice and humans.

Research in mice and human cells suggests that a fasting - mimicking diet may reprogram pancreas cells that are unable to produce insulin and enable them to repair themselves and start making it.

All animals use the same enzyme to create the same methylation mark as a signal for gene repression, and her colleagues who study epigenetics in mice and humans are excited about the new findings, Strome said.

Upon further investigation, they found that a tumour - suppressor gene called alternative reading frame (ARF), which is normally suppressed in mouse and human iPSCs, remained active in the mole - rat iPSCs.

«The fact that the vitamin B12 - taurine - bone pathway affects only bone formation and appears to play the same role in mice and human beings raises the prospect that targeting this pathway through pharmacological means could be a novel approach toward an anabolic treatment of osteoporosis.»

The simple solution appears to be to take DHEA to cure jet lag, but one important issue is that the circulating levels of DHEA in mice and humans is different.

Then investigators tested the 13 compounds in mouse and human cells and found that two compounds, OD36 and OD38, were most effective in blocking RIPK2.

After exposing both types of mice to endotoxin for two weeks, they tested their sensitivity to house dust mites, a common cause of allergies in both mice and humans.

The researchers used tools of epigenomic analysis to trace the specific epigenetic switches controlling each of thousands of genes in both mouse and human retinal cells as the cells progressed through development.

«Inflammatory signature of nonalcoholic fatty liver disease: Role of NKT and CD8 T - cells demonstrated in mice and humans.»

For the new mouse model, the researchers exposed adolescent mice with at least one copy of a variant of the BDNF gene, which has been associated with anorexia and anxiety in mice and humans, to social stress and caloric restriction.

Studying tissue samples, the researchers found that the nodules in both mice and human were rich in collagen VI.

Stem cells can currently only be cloned in mice and human cells.

Working in the lab and the clinic, Narayanan and his team record brain activity in mice and humans as they do simple timing tasks.