Sentences with phrase «in microbial systems»

Clement Furlong, a researcher in medical and genomic sciences at the University of Washington notes that the «huge advantage» of these heavy - chain - only antibodies «is that you can make them by fermentation in microbial systems and make a lot of antibodies inexpensively.»

Not exact matches

The treatment plant reduces the high levels of Suspended Solids (SS) and Biological Oxygen Demand (BOD) in the wastewater sufficiently to allow discharge into the local authority's sewerage system without the requirement for costly microbial after - treatment.
Understanding the role of each group of microbes in the breast milk would also provide leads to the pharmaceutical industry in harnessing microbial power to boost our immune system from various illnesses and allergies.
Government scientists have developed a biological system to keep microbial fuel producers from poisoning themselves in the process
The team, led by doctoral student Adam R. Burns, now a postdoctoral researcher at Stanford University, compared what they found in the fish with predictions from computer modeling of microbial dynamics performed by co-author Elizabeth Miller of the META Center for Systems Biology.
The oozy red slush of Blood Falls in Antarctica's McMurdo Dry Valleys contains teeming microbial life — and may be a sample of a deep briny groundwater system hundreds of meters below the surface.
They hypothesize that this system may control microbial overgrowth in the airway to maintain a colonized state within the upper airway without infection.
Because such chemistry provides energy for microbial life on Earth, the discovery makes Enceladus the top candidate for hosting life elsewhere in the solar system — besting even Jupiter's Europa, another icy moon with an ocean.
High up a Chilean volcano, there's more microbial diversity in bone - dry vents than icy patches - which could alter our search for life out in the solar system
The Systems Biology Group at the Pacific Northwest National Laboratory in Richland, Washington, employs 90 - plus staff scientists working on proteomics, microbial - cell dynamics, cell and molecular imaging and spectroscopy, computational biology, and bioinformatics.
The research also shows that the presence of microbial cheaters may help the soil system to react more flexibly to changes in environmental conditions.
An exhaust vent leading from one of the facility's «clean rooms» to the roof lacked a filter or screen, for example, and flaws in the air handling system could expose sterile drugs to microbial contamination during processing.
«In all of our studies, we're working with people who know the microbes well, and we help them decide how viruses might be helpful to the microbial system.
Systemic discovery of antiphage defense systems in the microbial pangenome.
When we think of how we fight disease, the image of cells in our immune system fending off microbial invaders often comes to mind.
Principle topics of the ocean margin systems workshop were microbial systems in sedimentary environments, fluid flow and subsurface material transport, margin building / regulating processes, and benthic population dynamics and relationships to sedimentary settings.
Andrew Steele uses traditional and biotechnological approaches for the detection of microbial life in astrobiology and solar system exploration.
The open source software package the researchers have designed, known as Microbial Dynamical Systems INference Engine (MDSINE), uses advanced machine learning technologies to accurately predict how microbial communities in the gut will grow and interact oMicrobial Dynamical Systems INference Engine (MDSINE), uses advanced machine learning technologies to accurately predict how microbial communities in the gut will grow and interact omicrobial communities in the gut will grow and interact over time.
The immune system maintains a rich abundance of «natural killer» cells to confront microbial invaders, but as the body gains the upper hand in various infections it sometimes starts to produce even more of the cells.
«The fact that we could alleviate inflammation by adding back a single key bacterial strain, suggests that it could be useful as a probiotic for inflammatory diseases,» said Rolig, who, along with Eisen, is a scientist in the National Institutes of Health - funded Microbial Ecology and Theory of Animals Center for Systems Biology, known as the META Center, which Guillemin heads.
Tilled systems that used a chisel plow were equivalent to no - till systems, in terms of microbial biomass.
When the data from all 62 studies were analyzed together, it turned out that microbial biomass and enzymatic activity were greater in no - till than in tilled systems.
«What we're trying to understand in the extreme systems is, what are the environmental drivers that are motivating the composition and structure of the [microbial] community?»
The study suggests that since soil microbial biomass and enzymatic activity can stand in as proxies for soil quality, farmers should consider moving toward no - till or conservation tillage systems.
The biggest mystery in the microbiome field is whether microbial changes are a cause or an effect of problems with the immune system, Dongari - Bagtzoglou says.
Finding out how methane and other organic species are formed in deep - sea hydrothermal systems is compelling because these compounds support modern day life, providing energy for microbial communities in the deep biosphere, and because of the potential role of abiotically - formed organic compounds in the origin of life.
«There's tons of questions around just how this whole system might control microbial populations in the gut, which have increasingly been shown to be important in obesity and diabetes, and all sorts of human conditions.»
About 30 years ago, scientists found a link between MS and certain variants in the major histocompatibility complex (MHC), a cluster of genes that help the immune system distinguish between the body's own proteins and those of microbial invaders.
«Mining sequence data in DOE JGI's Integrated Microbial Genomes & Microbiomes system, which houses thousands of metagenomes, allowed us to find evolutionary relatives of our Klosneuvirus,» Schulz said.
Nicholson (2006) has long been a proponent of the application of systems analysis to diagnostics and therapeutics, focusing, in particular, on the metabolome and its environmental (including microbial) modulation.
In a milestone for the medical and scientific community, he re-engineered the microbial CRISPR - Cas9 system for genome editing in human cellIn a milestone for the medical and scientific community, he re-engineered the microbial CRISPR - Cas9 system for genome editing in human cellin human cells.
Divergent assemblage patterns of abundant and rare microbial sub-communities in response to inorganic carbon stresses in a simultaneous anammox and denitrification (SAD) system — Duntao Shu, Bioresource Technology
Assessing the origin of bacteria in tap water and distribution system in an unchlorinated drinking water system by SourceTracker using microbial community fingerprints — Gang Liu — Water Research
But in the world of marine microbial ecology, there are very few model systems and associated tools that enable scientists to deeply explore the physiology, biochemistry, and ecology of marine microbes, which drive the ocean's elemental cycles, influence greenhouse gas levels, and support marine food webs.
She added, «New model systems will be a magnet for people from outside the field of marine microbial ecology as they will suddenly be able to work with marine microbes in ways that they are used to working with other model organisms.»
«Here we're cultivating an entire community of microbes to access enzymes that we couldn't get from isolates,» said study principal investigator Steve Singer, senior scientist in Berkeley Lab's Biological Systems and Engineering Division and director of Microbial and Enzyme Discovery at JBEI.
Dissertation: Understanding Microbial Community Dynamics in High - Solids Lignocellulolytic Systems Using Bioinformatics Tools — Joshua Thomas Claypool — University of California, Davis
«This is a tremendous innovation for in situ studies as a new means to interrogate the chemical language of microbial system interactions, as well as being relative to the discovery and development of new electrode materials for energy storage,» said Dr. Louis Terminello, who leads chemical imaging work at PNNL.
Charles Janeway introduces the hypothesis that «components of the innate [immune] system, especially antigen - presenting cells such as DCs, required the microbial stimuli contained in [adjuvants] to become activated and acquire the capacity to induce productive responses from antigen - specific lymphocytes.
This approach also can be applied to microbial mat and biofilm systems, where carbon isotopes can be measured at distinct layers in the system.
Biocellion is being used to model a variety of biological system behaviors, such as biofilm formation and wrinkling, microbial growth dynamics in complex soil structure, brain tumor growth and invasion, formation of complex bacterial colonies, and changes in blood vessels and skin cells.
This project addresses feedbacks between microbial matabolism and ecosystem processes in a forest soils, prairie potholes, river systems, and lakes.
Water and extremophile microbiome Seasonal variability in the persistence of dissolved environmental DNA (eDNA) in a marine system: The role of microbial nutrient limitation.
«More than 200 microbial species live in the digestive systems of cows and other ruminants,» says Karen Nelson, a microbial genomics researcher at TIGR.
Co-variation between Distribution of Microbial Communities and Biological Metabolization of Organics in Urban Sewer Systems.
He teamed with Dr. Janeway in the search for the gene in the innate immune system that activates the adaptive system — to address the questions, how does the human body know when it has an infection, and how does a microbial infection trigger an immune response?
«Due to their capacity for improving plant root growth, soil nutrient cycling and microbial activity, the application of humic substances may have long - term benefits in agricultural systems
Some, including variation in the immune system's response to microbial invaders, were expected.
KVM11, Isolated From Hydrocarbon Fed Microbial Electrochemical Remediation Systems — Krishnaveni Venkidusamy — Frontiers in Microbiology
Bordenstein is now examining whether certain microbial species are more important than others and how the presence of a foreign microbiome in a hybrid species alters its immune system.
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