Clement Furlong, a researcher in medical and genomic sciences at the University of Washington notes that the «huge advantage» of these heavy - chain - only antibodies «is that you can make them by fermentation
in microbial systems and make a lot of antibodies inexpensively.»
Not exact matches
The treatment plant reduces the high levels of Suspended Solids (SS) and Biological Oxygen Demand (BOD)
in the wastewater sufficiently to allow discharge into the local authority's sewerage
system without the requirement for costly
microbial after - treatment.
Understanding the role of each group of microbes
in the breast milk would also provide leads to the pharmaceutical industry
in harnessing
microbial power to boost our immune
system from various illnesses and allergies.
Government scientists have developed a biological
system to keep
microbial fuel producers from poisoning themselves
in the process
The team, led by doctoral student Adam R. Burns, now a postdoctoral researcher at Stanford University, compared what they found
in the fish with predictions from computer modeling of
microbial dynamics performed by co-author Elizabeth Miller of the META Center for
Systems Biology.
The oozy red slush of Blood Falls
in Antarctica's McMurdo Dry Valleys contains teeming
microbial life — and may be a sample of a deep briny groundwater
system hundreds of meters below the surface.
They hypothesize that this
system may control
microbial overgrowth
in the airway to maintain a colonized state within the upper airway without infection.
Because such chemistry provides energy for
microbial life on Earth, the discovery makes Enceladus the top candidate for hosting life elsewhere
in the solar
system — besting even Jupiter's Europa, another icy moon with an ocean.
High up a Chilean volcano, there's more
microbial diversity
in bone - dry vents than icy patches - which could alter our search for life out
in the solar
system
The
Systems Biology Group at the Pacific Northwest National Laboratory
in Richland, Washington, employs 90 - plus staff scientists working on proteomics,
microbial - cell dynamics, cell and molecular imaging and spectroscopy, computational biology, and bioinformatics.
The research also shows that the presence of
microbial cheaters may help the soil
system to react more flexibly to changes
in environmental conditions.
An exhaust vent leading from one of the facility's «clean rooms» to the roof lacked a filter or screen, for example, and flaws
in the air handling
system could expose sterile drugs to
microbial contamination during processing.
«
In all of our studies, we're working with people who know the microbes well, and we help them decide how viruses might be helpful to the
microbial system.
Systemic discovery of antiphage defense
systems in the
microbial pangenome.
When we think of how we fight disease, the image of cells
in our immune
system fending off
microbial invaders often comes to mind.
Principle topics of the ocean margin
systems workshop were
microbial systems in sedimentary environments, fluid flow and subsurface material transport, margin building / regulating processes, and benthic population dynamics and relationships to sedimentary settings.
Andrew Steele uses traditional and biotechnological approaches for the detection of
microbial life
in astrobiology and solar
system exploration.
The open source software package the researchers have designed, known as
Microbial Dynamical Systems INference Engine (MDSINE), uses advanced machine learning technologies to accurately predict how microbial communities in the gut will grow and interact o
Microbial Dynamical
Systems INference Engine (MDSINE), uses advanced machine learning technologies to accurately predict how
microbial communities in the gut will grow and interact o
microbial communities
in the gut will grow and interact over time.
The immune
system maintains a rich abundance of «natural killer» cells to confront
microbial invaders, but as the body gains the upper hand
in various infections it sometimes starts to produce even more of the cells.
«The fact that we could alleviate inflammation by adding back a single key bacterial strain, suggests that it could be useful as a probiotic for inflammatory diseases,» said Rolig, who, along with Eisen, is a scientist
in the National Institutes of Health - funded
Microbial Ecology and Theory of Animals Center for
Systems Biology, known as the META Center, which Guillemin heads.
Tilled
systems that used a chisel plow were equivalent to no - till
systems,
in terms of
microbial biomass.
When the data from all 62 studies were analyzed together, it turned out that
microbial biomass and enzymatic activity were greater
in no - till than
in tilled
systems.
«What we're trying to understand
in the extreme
systems is, what are the environmental drivers that are motivating the composition and structure of the [
microbial] community?»
The study suggests that since soil
microbial biomass and enzymatic activity can stand
in as proxies for soil quality, farmers should consider moving toward no - till or conservation tillage
systems.
The biggest mystery
in the microbiome field is whether
microbial changes are a cause or an effect of problems with the immune
system, Dongari - Bagtzoglou says.
Finding out how methane and other organic species are formed
in deep - sea hydrothermal
systems is compelling because these compounds support modern day life, providing energy for
microbial communities
in the deep biosphere, and because of the potential role of abiotically - formed organic compounds
in the origin of life.
«There's tons of questions around just how this whole
system might control
microbial populations
in the gut, which have increasingly been shown to be important
in obesity and diabetes, and all sorts of human conditions.»
About 30 years ago, scientists found a link between MS and certain variants
in the major histocompatibility complex (MHC), a cluster of genes that help the immune
system distinguish between the body's own proteins and those of
microbial invaders.
«Mining sequence data
in DOE JGI's Integrated
Microbial Genomes & Microbiomes
system, which houses thousands of metagenomes, allowed us to find evolutionary relatives of our Klosneuvirus,» Schulz said.
Nicholson (2006) has long been a proponent of the application of
systems analysis to diagnostics and therapeutics, focusing,
in particular, on the metabolome and its environmental (including
microbial) modulation.
In a milestone for the medical and scientific community, he re-engineered the microbial CRISPR - Cas9 system for genome editing in human cell
In a milestone for the medical and scientific community, he re-engineered the
microbial CRISPR - Cas9
system for genome editing
in human cell
in human cells.
Divergent assemblage patterns of abundant and rare
microbial sub-communities
in response to inorganic carbon stresses
in a simultaneous anammox and denitrification (SAD)
system — Duntao Shu, Bioresource Technology
Assessing the origin of bacteria
in tap water and distribution
system in an unchlorinated drinking water
system by SourceTracker using
microbial community fingerprints — Gang Liu — Water Research
But
in the world of marine
microbial ecology, there are very few model
systems and associated tools that enable scientists to deeply explore the physiology, biochemistry, and ecology of marine microbes, which drive the ocean's elemental cycles, influence greenhouse gas levels, and support marine food webs.
She added, «New model
systems will be a magnet for people from outside the field of marine
microbial ecology as they will suddenly be able to work with marine microbes
in ways that they are used to working with other model organisms.»
«Here we're cultivating an entire community of microbes to access enzymes that we couldn't get from isolates,» said study principal investigator Steve Singer, senior scientist
in Berkeley Lab's Biological
Systems and Engineering Division and director of
Microbial and Enzyme Discovery at JBEI.
Dissertation: Understanding
Microbial Community Dynamics
in High - Solids Lignocellulolytic
Systems Using Bioinformatics Tools — Joshua Thomas Claypool — University of California, Davis
«This is a tremendous innovation for
in situ studies as a new means to interrogate the chemical language of
microbial system interactions, as well as being relative to the discovery and development of new electrode materials for energy storage,» said Dr. Louis Terminello, who leads chemical imaging work at PNNL.
Charles Janeway introduces the hypothesis that «components of the innate [immune]
system, especially antigen - presenting cells such as DCs, required the
microbial stimuli contained
in [adjuvants] to become activated and acquire the capacity to induce productive responses from antigen - specific lymphocytes.
This approach also can be applied to
microbial mat and biofilm
systems, where carbon isotopes can be measured at distinct layers
in the
system.
Biocellion is being used to model a variety of biological
system behaviors, such as biofilm formation and wrinkling,
microbial growth dynamics
in complex soil structure, brain tumor growth and invasion, formation of complex bacterial colonies, and changes
in blood vessels and skin cells.
This project addresses feedbacks between
microbial matabolism and ecosystem processes
in a forest soils, prairie potholes, river
systems, and lakes.
Water and extremophile microbiome Seasonal variability
in the persistence of dissolved environmental DNA (eDNA)
in a marine
system: The role of
microbial nutrient limitation.
«More than 200
microbial species live
in the digestive
systems of cows and other ruminants,» says Karen Nelson, a
microbial genomics researcher at TIGR.
Co-variation between Distribution of
Microbial Communities and Biological Metabolization of Organics
in Urban Sewer
Systems.
He teamed with Dr. Janeway
in the search for the gene
in the innate immune
system that activates the adaptive
system — to address the questions, how does the human body know when it has an infection, and how does a
microbial infection trigger an immune response?
«Due to their capacity for improving plant root growth, soil nutrient cycling and
microbial activity, the application of humic substances may have long - term benefits
in agricultural
systems.»
Some, including variation
in the immune
system's response to
microbial invaders, were expected.
KVM11, Isolated From Hydrocarbon Fed
Microbial Electrochemical Remediation
Systems — Krishnaveni Venkidusamy — Frontiers
in Microbiology
Bordenstein is now examining whether certain
microbial species are more important than others and how the presence of a foreign microbiome
in a hybrid species alters its immune
system.