The PC3 vs. PC2 plot (panel b) illustrates the differences
in microbiome composition that exist among individual samples.
«Women with polycystic ovary syndrome have less bacterial diversity in gut: Study finds elevated testosterone levels in women linked to changes
in microbiome composition.»
«We were curious if the transmission of microbes is enough to explain the variation that we see
in the microbiome composition among individual fish.»
Not exact matches
In this study, researchers found that specific changes to maternal diet in the same woman (changing fat versus carbohydrate consumption, or changing consumption of specific sugars), is associated with changes in both the milk microbiome and human milk oligosaccharide (a carbohydrate) compositio
In this study, researchers found that specific changes to maternal diet
in the same woman (changing fat versus carbohydrate consumption, or changing consumption of specific sugars), is associated with changes in both the milk microbiome and human milk oligosaccharide (a carbohydrate) compositio
in the same woman (changing fat versus carbohydrate consumption, or changing consumption of specific sugars), is associated with changes
in both the milk microbiome and human milk oligosaccharide (a carbohydrate) compositio
in both the milk
microbiome and human milk oligosaccharide (a carbohydrate)
composition.
While the UniFrac analyses we performed suggest independent associations between
microbiome composition and both delivery mode and feeding method, the substantial overlap between the communities defined by both factors suggests that there are other important drivers of
microbiome community
composition that remain to be identified
in future analyses.
We evaluated the associations between the
composition of the 6 - week intestinal
microbiome and both delivery mode and feeding method
in 102 full - term, appropriately grown infants enrolled
in the New Hampshire Birth Cohort Study.
To our knowledge, our study was the first to examine the contribution of delivery mode to infant intestinal
microbiome composition in association with that of another important predictor of
microbiome composition, infant diet.
An emerging body of literature
in adults has begun to establish clear associations between gut microbiome composition and a wide range of health outcomes.1 - 6 In contrast, comparatively little is known about the gut microbiome in infants and children, the exposures that shape it, and its lifelong health effects.7 Although limited in their size and scope, a number of studies have established associations between intestinal microbiome profiles in infants, delivery mode, and / or breast milk exposure.8 - 15 These factors both have long - term health consequence
in adults has begun to establish clear associations between gut
microbiome composition and a wide range of health outcomes.1 - 6
In contrast, comparatively little is known about the gut microbiome in infants and children, the exposures that shape it, and its lifelong health effects.7 Although limited in their size and scope, a number of studies have established associations between intestinal microbiome profiles in infants, delivery mode, and / or breast milk exposure.8 - 15 These factors both have long - term health consequence
In contrast, comparatively little is known about the gut
microbiome in infants and children, the exposures that shape it, and its lifelong health effects.7 Although limited in their size and scope, a number of studies have established associations between intestinal microbiome profiles in infants, delivery mode, and / or breast milk exposure.8 - 15 These factors both have long - term health consequence
in infants and children, the exposures that shape it, and its lifelong health effects.7 Although limited
in their size and scope, a number of studies have established associations between intestinal microbiome profiles in infants, delivery mode, and / or breast milk exposure.8 - 15 These factors both have long - term health consequence
in their size and scope, a number of studies have established associations between intestinal
microbiome profiles
in infants, delivery mode, and / or breast milk exposure.8 - 15 These factors both have long - term health consequence
in infants, delivery mode, and / or breast milk exposure.8 - 15 These factors both have long - term health consequences.
Importance The intestinal
microbiome plays a critical role
in infant development, and delivery mode and feeding method (breast milk vs formula) are determinants of its
composition.
In a previous study of 24 healthy women, vaginal microbiome composition became less diverse between the second and third trimesters of pregnancy and just before delivery was enriched with Lactobacillus species, likely contributing to vertical transmission of these bacteria during vaginal birth.21 In a study of 10 newborns in Venezuela, within hours of delivery, the intestinal tracts of infants born vaginally were colonized by Lactobacillus and Prevotella, whereas infants delivered operatively acquired bacteria present on the mother's skin and the hospital environment, such as Staphylococcus, Proprionibacterium, and Corynebacterium.15 Quiz Ref ID Our findings, based on a large group of 6 - week - old infants, indicated that Lactobacillus also contributes to the microbial environment of the gut but to a lesser extent than Bifidobacteria, Bacteroides, and Streptococcu
In a previous study of 24 healthy women, vaginal
microbiome composition became less diverse between the second and third trimesters of pregnancy and just before delivery was enriched with Lactobacillus species, likely contributing to vertical transmission of these bacteria during vaginal birth.21
In a study of 10 newborns in Venezuela, within hours of delivery, the intestinal tracts of infants born vaginally were colonized by Lactobacillus and Prevotella, whereas infants delivered operatively acquired bacteria present on the mother's skin and the hospital environment, such as Staphylococcus, Proprionibacterium, and Corynebacterium.15 Quiz Ref ID Our findings, based on a large group of 6 - week - old infants, indicated that Lactobacillus also contributes to the microbial environment of the gut but to a lesser extent than Bifidobacteria, Bacteroides, and Streptococcu
In a study of 10 newborns
in Venezuela, within hours of delivery, the intestinal tracts of infants born vaginally were colonized by Lactobacillus and Prevotella, whereas infants delivered operatively acquired bacteria present on the mother's skin and the hospital environment, such as Staphylococcus, Proprionibacterium, and Corynebacterium.15 Quiz Ref ID Our findings, based on a large group of 6 - week - old infants, indicated that Lactobacillus also contributes to the microbial environment of the gut but to a lesser extent than Bifidobacteria, Bacteroides, and Streptococcu
in Venezuela, within hours of delivery, the intestinal tracts of infants born vaginally were colonized by Lactobacillus and Prevotella, whereas infants delivered operatively acquired bacteria present on the mother's skin and the hospital environment, such as Staphylococcus, Proprionibacterium, and Corynebacterium.15 Quiz Ref ID Our findings, based on a large group of 6 - week - old infants, indicated that Lactobacillus also contributes to the microbial environment of the gut but to a lesser extent than Bifidobacteria, Bacteroides, and Streptococcus.
Changes
in the
composition and activity of the gut
microbiome in early life can influence the immune system and these changes might indirectly lead to changes
in asthma later
in life,» said Dr. Anke Maitland - van der Zee, senior author of the study.
«Several studies have detected differences
in the
composition of the gut
microbiome between healthy people and those with obesity and type 2 diabetes, but the cause and effect remain unclear,» says Mark McCarthy, and continues:
If researchers can get a handle on the gut
microbiome's role, Baranzini can imagine a day when probiotics can be used to shift the
composition of microbes
in the gut to reduce inflammation.
«Through major genetics studies,» Borenstein noted, «scientists have made valuable progress
in gathering information on the species
composition of the human
microbiome in health and disease.»
Colonization by the human and animal parasite, Giardia, changed the species
composition of the mouse
microbiome in a way that might be harmful.
It's currently a challenge to do this kind of microbial redesign — antibiotics reduce microbial burden but fail to induce major changes
in bacterial
composition, and from fecal transplant studies
in the gut we know that bacterial populations return to a baseline population even after a major shift — so more work is needed to attempt a durable change
in the vaginal
microbiome.
Two groups of lactating women participated
in highly - controlled single - blinded cross-over dietary intervention studies to evaluate if maternal diet plays a significant role
in structuring the taxonomic and metagenomic
composition of the breast milk
microbiome.
During pregnancy and labor, antibiotics may change the
composition of bacteria
in a mother, and as a consequence, the
microbiome of the baby.
Both studies demonstrate that the
composition of the gut
microbiome — the swarms of microorganisms naturally dwelling
in the intestines — determines how effective these cancer immunotherapies are.
In another finding that is consistent with the practice of crop rotation, Fitzpatrick evaluated plant soil feedback and demonstrated that the more similar the composition of a plant's root microbiome to that of the previous generation of plant grown in that soil, the more the second - generation plant suffere
In another finding that is consistent with the practice of crop rotation, Fitzpatrick evaluated plant soil feedback and demonstrated that the more similar the
composition of a plant's root
microbiome to that of the previous generation of plant grown
in that soil, the more the second - generation plant suffere
in that soil, the more the second - generation plant suffered.
«If testosterone drives the microbial
composition of the gut, a compelling next step would be to determine if treatment of PCOS with testosterone blockers or oral contraceptives results
in the recovery of the gut
microbiome,» said Thackray.
Everything from being vegetarian to being born by cesarean section can change the
composition of our
microbiome in meaningful ways, she notes.
In both AP1 and AP2, the associations between the
composition of the
microbiome and specific inflammatory cytokines were decreased after treatment with an inhaled corticosteroid, a common asthma therapy.
Researchers at Harvard Medical School and Columbia University
in the United States have developed a way to study the functions of hard - to - grow bacteria that contribute to the
composition of the gut
microbiome.
They found that, while the species of bacteria present
in the gut
microbiome vary greatly between individuals, the
composition of the
microbiome is generally stable within the individual over time.
In turn, stress and emotions can change the
composition of the gut
microbiome.
HEIDELBERG, 11 March 2015 — Researchers at Harvard Medical School and Columbia University
in the United States have developed a way to study the functions of hard - to - grow bacteria that contribute to the
composition of the gut
microbiome.
This is evidence that a person's genes can influence the gut
microbiome's
composition and
in turn can shape the individual's phenotype.
However, the Weizmann researchers were surprised to discover that the host's genetics play a very minor role
in determining
microbiome composition — only accounting for about 2 % of the variation between populations.
Factors such as early environment, diet and antibiotic exposure have a lot to do with why people differ from one another
in the
composition of their
microbiomes.
In addition to genetic data and
microbiome composition, the information collected for each study participant included dietary habits, lifestyle, medications and additional measurements.
Her work combines fundamental innate immunology with molecular biology and she has reported extensively on the impact of innate immunity
in infection, autoimmunity, cancer,
microbiome composition and metabolic disorders.
In today's digest, check among many interesting articles: the evolution within human microbiome by T.D. Lieberman, unique microbial biodiversity residing in hadal trenches by L.M. Peoples, changes in community composition in coastal water following exposure to oil and oil dispersant by S.H. Doyl
In today's digest, check among many interesting articles: the evolution within human
microbiome by T.D. Lieberman, unique microbial biodiversity residing
in hadal trenches by L.M. Peoples, changes in community composition in coastal water following exposure to oil and oil dispersant by S.H. Doyl
in hadal trenches by L.M. Peoples, changes
in community composition in coastal water following exposure to oil and oil dispersant by S.H. Doyl
in community
composition in coastal water following exposure to oil and oil dispersant by S.H. Doyl
in coastal water following exposure to oil and oil dispersant by S.H. Doyle.
Fecal
microbiome composition and stability
in 4 - to 8 - year old children is associated with dietary patterns and nutrient intake — Kirsten Berding — The Journal of Nutritional Biochemistry
Gut
Microbiome Composition Predicts Infection Risk during Chemotherapy
in Children with Acute Lymphoblastic Leukemia — Hana Hakim — Clinical Infectious Diseases
Scientists have long known that plants impact the
composition of the soil
microbiome in the area surrounding their roots by sending out chemicals (metabolites).
The study, published July 21, 2016,
in Scientific Reports, also showed significant changes
in the gut
microbiome after antibiotic treatment, suggesting the
composition and diversity of bacteria
in the gut play an important role
in regulating immune system activity that impacts progression of Alzheimer's disease.
Another study from Sweden even demonstrated that the specific
microbiome composition occurring
in Alzheimer's patients induces the development of disease - specific amyloid - beta plaques, thereby establishing a direct functional link between the gut
microbiome and Alzheimer's disease — at least
in mice.
Human gut
microbiome Gut
microbiome composition in lean patients with NASH is associated with liver damage independent from caloric intake: a prospective pilot study — Sebastião Mauro Bezerra Duarte — Nutrition, Metabolism and Cardiovascular Diseases
The present study shows that ancient DNA is not entirely degraded
in humid, tropical environments, and that dietary and / or host genetic differences
in ancient populations may be reflected
in the
composition of their gut
microbiome.
Our
microbiome is as unique to us as a fingerprint and plays a role
in processes as diverse as body
composition, immune function, and mental health.
They looked for correlations between specific mutations
in the tumor cells and the
composition of the tumor
microbiome — the types of bacteria present
in the tumor's immediate environment and their relative abundance — and found relationships between the two.
They also plan to evaluate whether colorectal tumor
microbiome composition can be assayed from stool samples, and if this data can also be used to predict the type of mutations present
in the tumor cells.
The human
microbiome plays a role
in processes as diverse as body
composition, immune function, and mental health.
In terms of the overall composition of the fecal microbiome, however, differences may exist both in taxon distribution and relative abundance as a result of cultural or dietary habit
In terms of the overall
composition of the fecal
microbiome, however, differences may exist both
in taxon distribution and relative abundance as a result of cultural or dietary habit
in taxon distribution and relative abundance as a result of cultural or dietary habits.
Second, it implies that dietary and / or host genetic differences
in ancient populations may be reflected
in differences
in gut
microbiome composition and it confirms that the two indigenous cultures were indeed distinct.
«This is
in line with some of our recent studies which indicate that the GI tract
microbiome in Alzheimer's is significantly altered
in composition when compared to age - matched controls,» said Lukiw, who reviewed the new study but was not involved
in the research.
«One thing this suggests is that maybe the reason it's not more effective is that people need both cranberries and a higher urine pH, or they need cranberries and appropriate inhabitants of their intestine, or the right
microbiome composition in their gut, for the cranberry part to work properly.»
So, I know you mentioned gut
microbiome, but what about body
composition muscle mass
in response to uhm — postprandial glucose?
As shown
in FIG. 1A, a first method 100 for diagnosing and treating an autoimmune condition comprises: receiving an aggregate set of samples from a population of subjects S110; characterizing a
microbiome composition and / or functional features for each of the aggregate set of samples associated with the population of subjects, thereby generating at least one of a
microbiome composition dataset and a
microbiome functional diversity dataset for the population of subjects S120; receiving a supplementary dataset, associated with at least a subset of the population of subjects, wherein the supplementary dataset is informative of characteristics associated with the autoimmune condition S130; and transforming the supplementary dataset and features extracted from at least one of the
microbiome composition dataset and the
microbiome functional diversity dataset into a characterization model of the autoimmune condition S140.