Herein we propose a variant of Koch's postulates, aimed at providing a framework to establish causation
in microbiome studies, with a particular focus on demonstrating the health - promoting role of the commensal gut microbiota.
Researchers at the University of California Center for Microbiome Innovation (CMI) have validated a new method for use
in microbiome studies that...
Not exact matches
«It also brings
in the question of diet,» says Wargo, who is now working on new clinical
studies on the
microbiome with the Parker Institute for Cancer Immunotherapy.
In a recent study, researchers in Sweden came up with a mathematical formula to help find the right eating plan for each person based on his or her microbiom
In a recent
study, researchers
in Sweden came up with a mathematical formula to help find the right eating plan for each person based on his or her microbiom
in Sweden came up with a mathematical formula to help find the right eating plan for each person based on his or her
microbiome.
While we can't use sterile mice to make any definitive conclusions about humans, the twins
study, published
in the journal Science last year, provided clear evidence that the
microbiome is involved
in weight gain — something earlier research had only suggested.
The
study provides another example of the role of the
microbiome — the collection of microbes found
in and on the body —
in health and disease.
Even
in IBD patients, who have a very messed up
microbiome (a finding of the American Gut data), the benefits of antioxidant therapy is well documented (see below
studies).
I didn't see any evidence (1) actually connecting the former to the latter, (2) that the differences at birth are lasting, (3) that the purported diseases associated with the
microbiome in adulthood are the same ones associated with c - section (the author cites obesity, but we know that those observational
studies re: c - section and obesity are deeply flawed by confounding)(4) that the «microbiotic» benefit of vaginal birth exists regardless of maternal health and matenral
microbiome.
New
studies are showing that babies who not delivered vaginally lack exposure to certain
microbiomes in the birth canal that could cause trouble with metabolism and intestinal health, potentially making C - section babies more prone to having weight issues.
In this study, researchers found that specific changes to maternal diet in the same woman (changing fat versus carbohydrate consumption, or changing consumption of specific sugars), is associated with changes in both the milk microbiome and human milk oligosaccharide (a carbohydrate) compositio
In this
study, researchers found that specific changes to maternal diet
in the same woman (changing fat versus carbohydrate consumption, or changing consumption of specific sugars), is associated with changes in both the milk microbiome and human milk oligosaccharide (a carbohydrate) compositio
in the same woman (changing fat versus carbohydrate consumption, or changing consumption of specific sugars), is associated with changes
in both the milk microbiome and human milk oligosaccharide (a carbohydrate) compositio
in both the milk
microbiome and human milk oligosaccharide (a carbohydrate) composition.
«Further
studies are needed to delineate if specific changes
in maternal diet during breast - feeding alter the infant gut
microbiome and to determine if this results
in any health consequences for the infant,» said Kristen Meyer,
in the Department of Obstetrics and Gynecology at Baylor College of Medicine and the presenter of the
study at the SMFM annual conference.
Given that these two components of breast milk have the potential to alter the gut
microbiome of breast - feeding infants, the results of the
study suggest that development of the infant gut
microbiome may be affected
in part by what the mother eats during breastfeeding.
In a study to be presented Thursday, Jan. 26, in the oral plenary session at 1:15 p.m. PST, at the Society for Maternal - Fetal Medicine's annual meeting, The Pregnancy Meeting ™, researchers with Baylor College of Medicine, Houston, Texas and University of California, San Diego, La Jolla, California, will present their findings on a study titled, Maternal Diet Structures the Breast Milk Microbiome in Association with Human Milk Oligosaccharides and Gut - Associated Bacteri
In a
study to be presented Thursday, Jan. 26,
in the oral plenary session at 1:15 p.m. PST, at the Society for Maternal - Fetal Medicine's annual meeting, The Pregnancy Meeting ™, researchers with Baylor College of Medicine, Houston, Texas and University of California, San Diego, La Jolla, California, will present their findings on a study titled, Maternal Diet Structures the Breast Milk Microbiome in Association with Human Milk Oligosaccharides and Gut - Associated Bacteri
in the oral plenary session at 1:15 p.m. PST, at the Society for Maternal - Fetal Medicine's annual meeting, The Pregnancy Meeting ™, researchers with Baylor College of Medicine, Houston, Texas and University of California, San Diego, La Jolla, California, will present their findings on a
study titled, Maternal Diet Structures the Breast Milk
Microbiome in Association with Human Milk Oligosaccharides and Gut - Associated Bacteri
in Association with Human Milk Oligosaccharides and Gut - Associated Bacteria.
We evaluated the associations between the composition of the 6 - week intestinal
microbiome and both delivery mode and feeding method
in 102 full - term, appropriately grown infants enrolled
in the New Hampshire Birth Cohort
Study.
To our knowledge, our
study was the first to examine the contribution of delivery mode to infant intestinal
microbiome composition
in association with that of another important predictor of
microbiome composition, infant diet.
In addition, many
studies do not take into account the complex interaction of different fatty acid subtypes, such as omega - 3 and omega - 6 fatty acids, on gut inflammation as well as their effect on the intestinal
microbiome.
An emerging body of literature
in adults has begun to establish clear associations between gut microbiome composition and a wide range of health outcomes.1 - 6 In contrast, comparatively little is known about the gut microbiome in infants and children, the exposures that shape it, and its lifelong health effects.7 Although limited in their size and scope, a number of studies have established associations between intestinal microbiome profiles in infants, delivery mode, and / or breast milk exposure.8 - 15 These factors both have long - term health consequence
in adults has begun to establish clear associations between gut
microbiome composition and a wide range of health outcomes.1 - 6
In contrast, comparatively little is known about the gut microbiome in infants and children, the exposures that shape it, and its lifelong health effects.7 Although limited in their size and scope, a number of studies have established associations between intestinal microbiome profiles in infants, delivery mode, and / or breast milk exposure.8 - 15 These factors both have long - term health consequence
In contrast, comparatively little is known about the gut
microbiome in infants and children, the exposures that shape it, and its lifelong health effects.7 Although limited in their size and scope, a number of studies have established associations between intestinal microbiome profiles in infants, delivery mode, and / or breast milk exposure.8 - 15 These factors both have long - term health consequence
in infants and children, the exposures that shape it, and its lifelong health effects.7 Although limited
in their size and scope, a number of studies have established associations between intestinal microbiome profiles in infants, delivery mode, and / or breast milk exposure.8 - 15 These factors both have long - term health consequence
in their size and scope, a number of
studies have established associations between intestinal
microbiome profiles
in infants, delivery mode, and / or breast milk exposure.8 - 15 These factors both have long - term health consequence
in infants, delivery mode, and / or breast milk exposure.8 - 15 These factors both have long - term health consequences.
A separate
study found infants whose gestation lengths were less than 38 weeks had
microbiome communities that were low
in Bifidobacterium and took 3 to 6 months to reach a normal Bifidiobacterium - rich community as compared to infants born at 40 or more weeks [9].
In a previous study of 24 healthy women, vaginal microbiome composition became less diverse between the second and third trimesters of pregnancy and just before delivery was enriched with Lactobacillus species, likely contributing to vertical transmission of these bacteria during vaginal birth.21 In a study of 10 newborns in Venezuela, within hours of delivery, the intestinal tracts of infants born vaginally were colonized by Lactobacillus and Prevotella, whereas infants delivered operatively acquired bacteria present on the mother's skin and the hospital environment, such as Staphylococcus, Proprionibacterium, and Corynebacterium.15 Quiz Ref ID Our findings, based on a large group of 6 - week - old infants, indicated that Lactobacillus also contributes to the microbial environment of the gut but to a lesser extent than Bifidobacteria, Bacteroides, and Streptococcu
In a previous
study of 24 healthy women, vaginal
microbiome composition became less diverse between the second and third trimesters of pregnancy and just before delivery was enriched with Lactobacillus species, likely contributing to vertical transmission of these bacteria during vaginal birth.21
In a study of 10 newborns in Venezuela, within hours of delivery, the intestinal tracts of infants born vaginally were colonized by Lactobacillus and Prevotella, whereas infants delivered operatively acquired bacteria present on the mother's skin and the hospital environment, such as Staphylococcus, Proprionibacterium, and Corynebacterium.15 Quiz Ref ID Our findings, based on a large group of 6 - week - old infants, indicated that Lactobacillus also contributes to the microbial environment of the gut but to a lesser extent than Bifidobacteria, Bacteroides, and Streptococcu
In a
study of 10 newborns
in Venezuela, within hours of delivery, the intestinal tracts of infants born vaginally were colonized by Lactobacillus and Prevotella, whereas infants delivered operatively acquired bacteria present on the mother's skin and the hospital environment, such as Staphylococcus, Proprionibacterium, and Corynebacterium.15 Quiz Ref ID Our findings, based on a large group of 6 - week - old infants, indicated that Lactobacillus also contributes to the microbial environment of the gut but to a lesser extent than Bifidobacteria, Bacteroides, and Streptococcu
in Venezuela, within hours of delivery, the intestinal tracts of infants born vaginally were colonized by Lactobacillus and Prevotella, whereas infants delivered operatively acquired bacteria present on the mother's skin and the hospital environment, such as Staphylococcus, Proprionibacterium, and Corynebacterium.15 Quiz Ref ID Our findings, based on a large group of 6 - week - old infants, indicated that Lactobacillus also contributes to the microbial environment of the gut but to a lesser extent than Bifidobacteria, Bacteroides, and Streptococcus.
It would be interesting to see
studies about the seeding of
microbiome in infants who are born via cesarean section.
Oligosaccharides
in breast milk are thought to promote Bifidobacterium growth, 35 and decreased Bifidobacterium
in infancy has been found to be associated with an increased risk for being overweight at age 10 years.36 Many formulas are supplemented with prebiotics such as short - chain galacto - oligosaccharides and long - chain fructo - oligosaccharides that increase the overall representation of Bifidobacterium
in the
microbiome of formula - fed infants, and similar to breast milk, promote lactate and short - chain fatty acid prevalence
in the infant gut (reviewed
in the
study by Oozeer et al37).
A research
study released
in May, 2017 found that the bacteria found
in mother's milk and areolar skin seed the infant gut and profoundly influence the development of infant
microbiome.
«The
study advances our understanding of how the gut
microbiome develops early
in life,» Thompson said, «which is clearly a really important time period for a person's current and future health.»
Although the vast majority of research on the gut
microbiome has focused on bacteria
in the large intestine, a new
study — one of a few to concentrate on microbes
in the upper gastrointestinal tract — shows how the typical calorie - dense western diet can induce expansion of microbes that promote the digestion and absorption of high - fat foods.
«The newborn mice inherited a very altered, skewed population of microbes,» said Eugene B. Chang, MD, Martin Boyer Professor of Medicine at the University of Chicago, Director of the
Microbiome Medicine Program of the
Microbiome Center, and senior author of the
study, published this week
in the journal Cell Reports.
Animal
studies have started to show that the
microbiome, from its staging ground
in the bowel, can influence the development of its host's brain.
The first
microbiome study of the penis offers some clues as to why removing foreskin cuts the risk of HIV infection
in circumcised men
Ancient DNA analysis of
microbiomes is
in the early stages, but numerous
studies of the
microbiomes of today's traditional societies hint at what researchers may find.
«This is just the first
in what will likely be numerous
studies into the phage diversity of the urinary
microbiome,» said Dr. Putonti.
«Cultural revolution
in the
study of the gut
microbiome: Human gut - on - a-chip technology used to co-culture gut
microbiome, human intestinal cells could lead to new therapies for inflammatory bowel diseases.»
«This technology enables one to
study in an isolated and controlled manner the complexity of the
microbiome and the role different microbial species play
in health and disease.
A new
study shows that the microbial communities we carry
in and on our bodies — known as the human
microbiome — have the potential to uniquely identify individuals, much like a fingerprint.
The
study found that a queen's
microbiome does not change when placed
in a new colony — and the colony's
microbiome doesn't change either.
Five years ago, Tim Spector of Kings College London attended a presentation of the results of a
study in twins that suggested a person's genes don't affect their
microbiome.
Treatment implications were examined
in a series of human
studies that demonstrated similar reductions
in the
microbiome in participants suffering from both major depression and bipolar disorder.
Published last week
in Cell, a
study by Santamaria and Kathy McCoy, PhD, from the University of Calgary's Cumming School of Medicine (CSM) reveals a new mechanism
in the gut
microbiome that regulates pro- and anti-inflammatory cells.
By
studying individuals over time, Dr. Chadi Calarge was able to examine
microbiome changes when individuals were depressed or
in remission, and when they were and were not receiving anti-depressant medications (SSRIs).
Study after study has shown how the microbes living in us and on us — the microbiome — can affect our health and even happi
Study after
study has shown how the microbes living in us and on us — the microbiome — can affect our health and even happi
study has shown how the microbes living
in us and on us — the
microbiome — can affect our health and even happiness.
Through projects at Duke Health, DCRI and the Duke Center for Childhood Obesity Research, Armstrong and other Duke scientists are assessing the most effective strategies to reduce obesity
in children, including programs that offer at - risk children access to free medical care, partnerships with municipal recreation programs across North Carolina, and even
studying children's gut bacteria to determine how the gut
microbiome is related to weight.
In a related study also published today in PNAS, immunologists led by Gurumoorthy Krishnamoorthy and Hartmut Wekerle of the Max Planck Institute of Neurobiology in Martinsried, Germany, examined the gut microbiomes of 34 sets of identical twins, aged 21 to 63, in which only one twin had MS.. They found that Akkermansia was slightly but significantly more abundant in MS patients than in their healthy twin
In a related
study also published today
in PNAS, immunologists led by Gurumoorthy Krishnamoorthy and Hartmut Wekerle of the Max Planck Institute of Neurobiology in Martinsried, Germany, examined the gut microbiomes of 34 sets of identical twins, aged 21 to 63, in which only one twin had MS.. They found that Akkermansia was slightly but significantly more abundant in MS patients than in their healthy twin
in PNAS, immunologists led by Gurumoorthy Krishnamoorthy and Hartmut Wekerle of the Max Planck Institute of Neurobiology
in Martinsried, Germany, examined the gut microbiomes of 34 sets of identical twins, aged 21 to 63, in which only one twin had MS.. They found that Akkermansia was slightly but significantly more abundant in MS patients than in their healthy twin
in Martinsried, Germany, examined the gut
microbiomes of 34 sets of identical twins, aged 21 to 63,
in which only one twin had MS.. They found that Akkermansia was slightly but significantly more abundant in MS patients than in their healthy twin
in which only one twin had MS.. They found that Akkermansia was slightly but significantly more abundant
in MS patients than in their healthy twin
in MS patients than
in their healthy twin
in their healthy twins.
«
Study points to penile
microbiome as a risk factor for HIV
in men.»
Changes
in the composition and activity of the gut
microbiome in early life can influence the immune system and these changes might indirectly lead to changes
in asthma later
in life,» said Dr. Anke Maitland - van der Zee, senior author of the
study.
This
study that has been ongoing since 2013, Study of the Impact of Long - Term Space Travel on the Astronauts» Microbiome, Microbiome for short, investigates how space travel affects the human immune system and an individual's microbiome, which is the collection of microbes that live in and on the human body at any given
study that has been ongoing since 2013,
Study of the Impact of Long - Term Space Travel on the Astronauts» Microbiome, Microbiome for short, investigates how space travel affects the human immune system and an individual's microbiome, which is the collection of microbes that live in and on the human body at any given
Study of the Impact of Long - Term Space Travel on the Astronauts»
Microbiome, Microbiome for short, investigates how space travel affects the human immune system and an individual's microbiome, which is the collection of microbes that live in and on the human body at any g
Microbiome,
Microbiome for short, investigates how space travel affects the human immune system and an individual's microbiome, which is the collection of microbes that live in and on the human body at any g
Microbiome for short, investigates how space travel affects the human immune system and an individual's
microbiome, which is the collection of microbes that live in and on the human body at any g
microbiome, which is the collection of microbes that live
in and on the human body at any given time.
Earlier
studies have linked the human
microbiome — that is, the collection of microbes living
in and on the human body — to a variety of health conditions, but little is known about the role of the penile
microbiome as it relates to men's health.
Managing the
microbiome instead of pummeling it with antibiotics has produced impressive results
in chicken and mice
studies, pointing the way not just to future human treatments but also to a healthier food supply.
The Duke
study is just one of many projects begun
in the past five years that use genetic sequencing to explore how the diversity of the
microbiome impacts our health.
«Several
studies have detected differences
in the composition of the gut
microbiome between healthy people and those with obesity and type 2 diabetes, but the cause and effect remain unclear,» says Mark McCarthy, and continues:
«The only way to answer this is with a really big sample of cadavers,» says Sibyl Bucheli of the Sam Houston State University
in Huntsville, Texas, who is also
studying the death
microbiome.
«Our
study has the potential to help future
studies explore novel insights into a possible role of the
microbiome in the increased risk for eye infections
in contact lens wearers,» Dominguez - Bello said.
The
study adds to knowledge of how microbes colonize our skin and how much our microbial communities — or
microbiomes — change when we contact other people or surfaces, whether it's a doorknob at home or medical equipment
in a hospital.