Sentences with phrase «in model animals»

Not exact matches

Our study in an animal model found that influenza infection leads to an increase in the expression of muscle - degrading genes and a decrease in expression of muscle - building genes in skeletal muscles in the legs.

Two other hooded sweatshirts in the line, one that says «Survival Expert» and one covered in an animal - shape print, were modeled by white children.

Actress Rosanna Arquette, model Kathy Ireland and animal behaviourist Jackson Galaxy of «My Cat From Hell» are among the celebrities who pen love notes to their cats in this collection.

In the animal models, that can lead to an increase in blood sugar spikes which can lead to diabeteIn the animal models, that can lead to an increase in blood sugar spikes which can lead to diabetein blood sugar spikes which can lead to diabetes.

PPAR gamma agonists have shown strong potential in animal models related to the various phenotypes associated with X-ALD.

It is customary and even ethically mandatory that experimentation that carries with it a substantial degree of risk to human subjects first be tested in an animal laboratory or, at the very least, on a computer model.

As I stated in my original article, prior to conducting experiments with human cells, ANT - OAR techniques would need to be rigorously tested in animal models to establish a procedure that guarantees with reasonable certainty that an embryo is not generated.

We are to model our lives after Christ, the Son of God, who though he was God's very equal, came to earth, was born in an animal's feeding stall and died on a cross.

In many animal model systems, for example, the precise genes involved in sexual partner selection have been identified, and their neuro - biochemical pathways have been worked out in great detaiIn many animal model systems, for example, the precise genes involved in sexual partner selection have been identified, and their neuro - biochemical pathways have been worked out in great detaiin sexual partner selection have been identified, and their neuro - biochemical pathways have been worked out in great detaiin great detail.

It is stated that in the beginning God made woman equal in nature to man, on his model, in distinction to all animals.

[104] In place of WS, animal protectionists hold up their work with sheep producers of Marin County, California as a better coyote management model.

In the ecological model the elements in the cell relate to one another and to the cell as a whole, more like the way an animal as a whole relates to its environmenIn the ecological model the elements in the cell relate to one another and to the cell as a whole, more like the way an animal as a whole relates to its environmenin the cell relate to one another and to the cell as a whole, more like the way an animal as a whole relates to its environment.

-LCB- Project -RCB- COWCALF: Developing robust and economically viable models for cow - calf suckling in organic dairy systems, fulfilling high standards for animal health, welfare and ethics.

Dihydrocaffeic acid and malvidin - 3» - O - glucoside were used as a «prophylactic and therapeutic» treatment in an animal model.

To evaluate a model system of inspection, operating under HACCP principles, a third inspection system known as HACCP - based Inspection Models Project (HIMP) was initiated in 1998 to evaluate the ability of the HIMP model to improve the safety of processed animals and poultry.

What sorts of mental lives do animals have, and how should we understand welfare?By presenting models for understanding animals» moral status and rights, and examining their mental lives and welfare, David DeGrazia explores the implications for how we should treat animals in connection wi...

Headquartered in La Mirada, Calif., its specialized market segments encompass six distinct distribution business units: FoodTech, Nutraceuticals, Animal Wellness, Advanced Materials, Coatings and Building Materials and Care Elements For more than 50 years, HORN's entrepreneurial approach to customer service embraces challenge and opens opportunities to reinvent and improve on traditional business models.

It is currently playing out in the live animal export sector, where the demise of local processing opened the door for a live export sector, which in turn through its simple business model has compromised livestock welfare and alienated many consumers, reduced employment in Top End towns which once had abattoirs, and added risk to cattle business profitability by providing only one market outlet.

4) Wheat germ agglutinin, a direct intestinal toxin in animal models, exerts disruptive effects on gastric, small intestinal, and colonic mucosa.

Their dinosaurs and animal models are by far the best I have come across in my almost 10 years of being a parent.

Because this exersaucer has a three - position height adjustment, though, it is likely that at some point you'll see your baby happily jumping up and down while looking in the mirror, shaking the rattle or gripping the stuffed animal that's connected to, and detachable from, this model.

Although most of these biosubstances have been identified in mother's milk in quantities that exceed maternal serum levels, their exact role in human newborns is uncertain; most current information is from animal models whose development may significantly differ.

In animal models, long - term fluoxetine administration blocks the oxytocin release induced by serotonergic drugs.14

They then tested the contributions of samples from breast milk as well as individual molecules in both animal and cellular models of infection, measuring the length of time until resolution.

Based on animal models, including a primate model, it is hypothesized that the cells remain unharmed in the digestive tract of the infant then enter the bloodstream, migrate to different organs, and there provide active immunity.54

Researchers examine correlations to develop testable hypotheses that can be examined in non-human animal models.

In animal models, exposure to cigarette smoke or nicotine during fetal development alters the expression of the nicotinic acetylcholine receptor in areas of the brainstem important for autonomic function, 28 alters the neuronal excitability of neurons in the nucleus tractus solitarius (a brainstem region important for sensory integration), 29 and alters fetal autonomic activity and medullary neurotransmitter receptors.30 In human infants, there are strong associations between nicotinic acetylcholine receptor and serotonin receptors in the brainstem during development.31 Prenatal exposure to tobacco smoke attenuates recovery from hypoxia in preterm infants, 32 decreases heart rate variability in preterm33 and term34 infants, and abolishes the normal relationship between heart rate and gestational age at birth.33 Moreover, infants of smoking mothers exhibit impaired arousal patterns to trigeminal stimulation in proportion to urinary cotinine levels.35 It is important to note also that prenatal exposure to tobacco smoke alters the normal programming of cardiovascular reflexes such that there is a greater - than - expected increase in blood pressure and heart rate in response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDIn animal models, exposure to cigarette smoke or nicotine during fetal development alters the expression of the nicotinic acetylcholine receptor in areas of the brainstem important for autonomic function, 28 alters the neuronal excitability of neurons in the nucleus tractus solitarius (a brainstem region important for sensory integration), 29 and alters fetal autonomic activity and medullary neurotransmitter receptors.30 In human infants, there are strong associations between nicotinic acetylcholine receptor and serotonin receptors in the brainstem during development.31 Prenatal exposure to tobacco smoke attenuates recovery from hypoxia in preterm infants, 32 decreases heart rate variability in preterm33 and term34 infants, and abolishes the normal relationship between heart rate and gestational age at birth.33 Moreover, infants of smoking mothers exhibit impaired arousal patterns to trigeminal stimulation in proportion to urinary cotinine levels.35 It is important to note also that prenatal exposure to tobacco smoke alters the normal programming of cardiovascular reflexes such that there is a greater - than - expected increase in blood pressure and heart rate in response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDin areas of the brainstem important for autonomic function, 28 alters the neuronal excitability of neurons in the nucleus tractus solitarius (a brainstem region important for sensory integration), 29 and alters fetal autonomic activity and medullary neurotransmitter receptors.30 In human infants, there are strong associations between nicotinic acetylcholine receptor and serotonin receptors in the brainstem during development.31 Prenatal exposure to tobacco smoke attenuates recovery from hypoxia in preterm infants, 32 decreases heart rate variability in preterm33 and term34 infants, and abolishes the normal relationship between heart rate and gestational age at birth.33 Moreover, infants of smoking mothers exhibit impaired arousal patterns to trigeminal stimulation in proportion to urinary cotinine levels.35 It is important to note also that prenatal exposure to tobacco smoke alters the normal programming of cardiovascular reflexes such that there is a greater - than - expected increase in blood pressure and heart rate in response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDin the nucleus tractus solitarius (a brainstem region important for sensory integration), 29 and alters fetal autonomic activity and medullary neurotransmitter receptors.30 In human infants, there are strong associations between nicotinic acetylcholine receptor and serotonin receptors in the brainstem during development.31 Prenatal exposure to tobacco smoke attenuates recovery from hypoxia in preterm infants, 32 decreases heart rate variability in preterm33 and term34 infants, and abolishes the normal relationship between heart rate and gestational age at birth.33 Moreover, infants of smoking mothers exhibit impaired arousal patterns to trigeminal stimulation in proportion to urinary cotinine levels.35 It is important to note also that prenatal exposure to tobacco smoke alters the normal programming of cardiovascular reflexes such that there is a greater - than - expected increase in blood pressure and heart rate in response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDIn human infants, there are strong associations between nicotinic acetylcholine receptor and serotonin receptors in the brainstem during development.31 Prenatal exposure to tobacco smoke attenuates recovery from hypoxia in preterm infants, 32 decreases heart rate variability in preterm33 and term34 infants, and abolishes the normal relationship between heart rate and gestational age at birth.33 Moreover, infants of smoking mothers exhibit impaired arousal patterns to trigeminal stimulation in proportion to urinary cotinine levels.35 It is important to note also that prenatal exposure to tobacco smoke alters the normal programming of cardiovascular reflexes such that there is a greater - than - expected increase in blood pressure and heart rate in response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDin the brainstem during development.31 Prenatal exposure to tobacco smoke attenuates recovery from hypoxia in preterm infants, 32 decreases heart rate variability in preterm33 and term34 infants, and abolishes the normal relationship between heart rate and gestational age at birth.33 Moreover, infants of smoking mothers exhibit impaired arousal patterns to trigeminal stimulation in proportion to urinary cotinine levels.35 It is important to note also that prenatal exposure to tobacco smoke alters the normal programming of cardiovascular reflexes such that there is a greater - than - expected increase in blood pressure and heart rate in response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDin preterm infants, 32 decreases heart rate variability in preterm33 and term34 infants, and abolishes the normal relationship between heart rate and gestational age at birth.33 Moreover, infants of smoking mothers exhibit impaired arousal patterns to trigeminal stimulation in proportion to urinary cotinine levels.35 It is important to note also that prenatal exposure to tobacco smoke alters the normal programming of cardiovascular reflexes such that there is a greater - than - expected increase in blood pressure and heart rate in response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDin preterm33 and term34 infants, and abolishes the normal relationship between heart rate and gestational age at birth.33 Moreover, infants of smoking mothers exhibit impaired arousal patterns to trigeminal stimulation in proportion to urinary cotinine levels.35 It is important to note also that prenatal exposure to tobacco smoke alters the normal programming of cardiovascular reflexes such that there is a greater - than - expected increase in blood pressure and heart rate in response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDin proportion to urinary cotinine levels.35 It is important to note also that prenatal exposure to tobacco smoke alters the normal programming of cardiovascular reflexes such that there is a greater - than - expected increase in blood pressure and heart rate in response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDin blood pressure and heart rate in response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDin response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDin autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDS.

10 There is no animal model of SIDS and it has never been observed to occur naturally in any species other than humans.2 While the standardization of a SIDS diagnosis has been and continues to be elusive and / or inconsistent, it is most often applied to situations in which an otherwise healthy infant between the ages of 8 - 16 weeks, especially, but up to 12 months, dies suddenly and unexpectedly presumably during its sleep and upon postmortem examination no apparent internal causal factor (s) explaining the death can be identified.11, 12

Prosecuting would be a «difficult and unworkable task, as little or no evidence is available regarding [the substances»] pharmacological activities in vivo in humans and expert witnesses may be reluctant to extrapolate data from animal models, in silico or in vitro studies,» lecturer in criminal law Amber Marks told the committee.

The Dr Hadwen Trust for Humane Research claims that «in some instances, reliance on inaccurate animal «models» of human disease have undoubtedly delayed medical progress.»

In 1859, Charles Darwin's evolutionary theory reinforced the conception that animals could serve as models for humans in the study of biology and physiologIn 1859, Charles Darwin's evolutionary theory reinforced the conception that animals could serve as models for humans in the study of biology and physiologin the study of biology and physiology.

Wooden model of naked prime minister with animal's head follows claims of dining club initiation in book by Lord Ashcroft

Studies show that these models can accurately predict the ways that new drugs will react in the human body and replace the use of animals in exploratory research and many standard drug tests.

Initial studies conducted by Christine Radtke, new Professor for Plastic and Reconstructive Surgery at MedUni Vienna / Vienna General Hospital, have shown in an animal model that the threads have great potential for nerve and tissue repair.

In an animal model, this technique successfully repaired nerve damage over distances of up to 6 cm: the nerve fibres grew back together in a functional way within 9 monthIn an animal model, this technique successfully repaired nerve damage over distances of up to 6 cm: the nerve fibres grew back together in a functional way within 9 monthin a functional way within 9 months.

This week in Nature Communications, an interdisciplinary team of scientists proposes a more nuanced model for extinction that also shows why animal species tend to evolve toward larger body sizes.

«By studying how education changes the brain, we can find out how this uniquely human experience induces change in both brain structure and function — something we can not do with animal models.»

New research from an international group led by Min Zhao, professor of ophthalmology and of dermatology at the University of California, Davis, shows that, in animal models of diabetes, slow healing is associated with weaker electrical currents in wounds.

To better understand their findings, the team examined the animal model for APS1 (i.e. mice with the same genetic defect as human patients with the syndrome) and found that male mice spontaneously developed an inflammatory disease in their prostate glands — a so - called prostatitis — and reacted to transglutaminase 4.

The search for more of these factors is complicated by the rarity of brain samples from suicide victims and the lack of an animal model — humans are unique in their wilful ability to end their lives.

«Candidate drug provides benefit in spinal muscular atrophy animal models.»

To probe the brain circuitry involved in this signal, and to assess the role of the cerebellum, the team turned to an animal model.

Using gene editing to create rodents that are ideal research models could narrow the genetic divide between humans and their animal stand - ins.

These findings allowed researchers to create a chimera virus: a mouse virus with a human viral gene that can be used to test molecules that inhibit human LANA protein in an animal model of disease, treating not only human herpes virus infection but also its associated cancers.

Researchers at the University of Missouri developed a new molecule in April 2014 that was found to be highly effective in animal models exhibiting SMA.

Further studies in animal models and patients (with altered TRPM7 channel function) have been initiated, in order to evaluate the efficacy and safety of magnesium as a therapeutic for this disease.

In a paper published in the journal Systematic Biology and delivered at the Society for Molecular Biology and Evolution Conference this week, Dr Phillips said biases in models of DNA evolution inflated estimates of when modern mammals, which were once no larger than a guinea pig, diversified and evolved into the animals familiar to us todaIn a paper published in the journal Systematic Biology and delivered at the Society for Molecular Biology and Evolution Conference this week, Dr Phillips said biases in models of DNA evolution inflated estimates of when modern mammals, which were once no larger than a guinea pig, diversified and evolved into the animals familiar to us todain the journal Systematic Biology and delivered at the Society for Molecular Biology and Evolution Conference this week, Dr Phillips said biases in models of DNA evolution inflated estimates of when modern mammals, which were once no larger than a guinea pig, diversified and evolved into the animals familiar to us todain models of DNA evolution inflated estimates of when modern mammals, which were once no larger than a guinea pig, diversified and evolved into the animals familiar to us today.

The findings are interesting, says René Hen, a neuroscientist who studies depression at Columbia University in New York, but «animal models of depression are very imperfect.»

Based on their findings, they urge that «mosquito saliva and enhancing antibodies thus need to be considered when developing vaccines and drugs against dengue,» and specifically suggest that «animal models of dengue and pre-clinical validation of dengue vaccine candidates should be evaluated in the combined presence of mosquito saliva and enhancing antibodies.»

In medicine today, physician - scientists and basic scientists supplement support for their research by applying their expertise part time to develop and test commercial products.1 In my own field, vision science, university - based researchers obtain additional funding through clinical and electrophysiologic studies, pathology, imaging, biochemistry, and animal model development performed for pharmaceutical and instrument companies.