Sentences with phrase «in model systems»

So what you do in the model systems is you create one mutation, or a series of mutations, which makes those organisms resistant to the action of insulin.

Researchers either purchase or generate their own antibodies to detect proteins in their model systems.

What I would like to see posted would be an extension of your maths section to show the methods used to calculate the effect of changing the concentration of CO2 in a model system.

They are devoted to identifying novel disease genes, elucidating disease mechanisms in model systems, and developing innovative methods for diagnostics.

Researchers at Penn State University have developed an innovative technology to regenerate functional neurons after brain injury, and also in model systems used for research on Alzheimer's disease.

Researchers at Penn State University led by biologist Gong Chen have developed an innovative technology to regenerate functional neurons after brain injury, and also in model systems used for research on Alzheimer's disease.

We have characterized mitochondrial SRS and, through its mutation, we have generated a Drosophila model that can be used as a proxy for human mitochondrial disease in a model system that is easy to manipulate.

Researchers were able to mutate Viral Protein 40 (VP40) in a way that changed the residues of the protein, blocking the budding and replication of Ebola virus in a model system.

The researchers have identified a compound that reverses the reprogramming and prevents tumor formation in model systems.

As it matures, the authors wrote, it is moving «from laboratory - based experimental studies in model systems to a mature discipline that is yielding products that are being evaluated and used in the clinical domain.

Gerken spent months studying and optimizing each component of the setup they had envisioned before testing everything in a model system.

«Studying these effects in model systems such as rats and flies allows us to address these questions by manipulating the likely mechanisms involved, which we can't do in humans.»

«It's a step up in the transgenic technology that's available in this model system that opens up new pathways of analysis.»

Blocking TAM receptors via different routes of administration, including giving it as an oral «pill», markedly reduced metastatic spreading in our model systems,» says Magdalena Paolino, first author of the study.

It has been known for decades that warfarin, the most widely used anticoagulant worldwide, reduces tumor metastasis in model systems.

They determined which ones accurately mimicked real gangliosides, partitioning into rafts in the model system.

The study revealed that in the model system chosen by Opitz and colleagues the winning side becomes apparent at a very early stage in the growth of the population, when the numbers of cells are still relatively small.

Important information on such physical systems can be gained by recreating similar conditions in a model system, like the atom clouds.

They showed that the Cd14 molecule plays a protective role in their model system of intestinal function in mice.

Solidification under sedimentation: The dynamic map illustrates the speed of the particles in the model system.

In addition, they found that in their model system with high energy and at small scale, the system was much more likely to return multiple particles upon sending in just one, than to come out with the initial particle and no more, which was a huge surprise.

We then establish a quantitative «constant - kink - saturation» relation between χaa and the fill factor in organic solar cells that is verified in detail in a model system and delineated across numerous high - and low - performing materials systems, including fullerene and non-fullerene acceptors.

As the Mainz researchers found in their model system, it is possible to customize the asymmetric field pulses that provide the forward - and backward - oriented forces that act on domain walls.

In the past, we have identified a candidate cancer signature in this model system, and validated it against «real» human cancers (23).

We are actively working on increasing CdTe open circuit voltage, under the auspices of SuNLaMP, with demonstrated success already in model systems.

Dr. Locksley's laboratory focuses on tracking cytokine expression in model systems, as a mechanism to investigate complex functional interactions between innate and adaptive cells in the immune system.

«Given the long and established history of curcumin as a spice and herbal medicine, its demonstrated chemopreventive and therapeutic potential, and its pharmacological safety in model system, curcumin, the bioactive extract of curcumin, promises a great future in human clinical studies designed to prevent and / or delay age - related diseases,» explained the authors of a review on these and other animal studies involving curcumin.

There are very few examples of well - defined circuitries and molecular mechanisms in any model system, for the integration of arousal state and output behaviors.

And we've learned a lot about that in model systems, such as in fruit flies, worms, and mice.

Lieberman's team noted that in their model system, parasites began to die within 15 to 30 minutes, while the human or mouse cells they infected died some 45 minutes to an hour later.

In our model system, MMPs are required in both blood and in epithelia, as animals lacking MMPs in either tissue can not heal puncture wounds.