Sentences with phrase «in mouse eye»

Mao's study examined mitochondria - associated gene expression in the mouse eye tissue and found significant changes in several genes involved in oxidative stress response.

The study's lead investigator, Tom Reh, Ph.D., and his team at the UW Medicine in Seattle, looked to the zebrafish for clues about how to encourage regeneration in the mouse eye.

Abstract Title: Baicalein lowers intraocular pressure and increases outflow facility in mouse eye.

Not exact matches

But that's like believing that the first Mickey Mouse cartoons were really moving images when in fact the animation was created by moving from one image to another so rapidly the eye was fooled.

I am happy that the eye mouse is developed in Korea.

That was the message that Hyung - Jin Shin sent out today in Seoul, South Korea, with the help of Samsung's «eye mouse,» or Eyecan +, The Verge reports.

Using the gene - editing tool CRISPR - Cas9 to turn off certain genes in a mouse zygote as well as other new techniques to enrich the pluripotent stem cells of a rat, the group managed to grow various rat organs (a pancreas, heart, and eyes) in a mouse embryo.

«Once implanted in surrogate mouse mothers, the embryos developed normally — except for the fact that each mouse was growing a rat pancreas» [or heart, or eyes], said the Salk Institute's own news analysis — which, incidentally, called the Salk team's paper a «tour de force.»

as he follows the tracks of the skunk in the January snow; wondering where the skunk is beading and why; speculating on the different meanings of a winter thaw for the mouse whose snow burrow has collapsed and the owl who has just made dinner on the mouse; trying to understand the honking of the geese as they circle the pond; and wondering what the world must look like to a muskrat eye - deep in the swamp.

When tissue from the jaw region of a chick embryo is wrapped in tissue from a mouse embryo from the region where teeth are formed and then incubated in the eye of an adult mouse, the chick develops teeth.

A study published in the October, 1999 issue of the Archives of Environmental Health found that laboratory mice exposed to various brands of disposable diapers suffered increased eye, nose, and throat irritation, including bronchoconstriction similar to that of an asthma attack.

Another study published in 1999 by Anderson Laboratories found that lab mice exposed to various brands of disposable diapers experienced asthma - like symptoms, as well as eye, nose and throat irritation.

The researchers found that these electric currents were much weaker in eyes from all three strains of diabetic mice than in healthy mice.

One of the research lines that John, an investigator of the Howard Hughes Medical Institute (HHMI) and a professor at The Jackson Laboratory in Bar Harbor, Maine, currently has going is the development of a wireless sensor so tiny it can be implanted into the eye of a mouse.

Experimenting with mice, neuroscientists at Johns Hopkins Medicine report new evidence that the eye's iris in many lower mammals directly senses light and causes the pupil to constrict without involving the brain.

In the new work, published June 10 in the journal Scientific Reports, Zhao, Reid and colleagues used a highly sensitive probe to measure electrical fields in the corneas of isolated eyes from three different lab mouse models with different types of diabetes: genetic, drug - induced and in mice fed a high - fat dieIn the new work, published June 10 in the journal Scientific Reports, Zhao, Reid and colleagues used a highly sensitive probe to measure electrical fields in the corneas of isolated eyes from three different lab mouse models with different types of diabetes: genetic, drug - induced and in mice fed a high - fat diein the journal Scientific Reports, Zhao, Reid and colleagues used a highly sensitive probe to measure electrical fields in the corneas of isolated eyes from three different lab mouse models with different types of diabetes: genetic, drug - induced and in mice fed a high - fat diein the corneas of isolated eyes from three different lab mouse models with different types of diabetes: genetic, drug - induced and in mice fed a high - fat diein mice fed a high - fat diet.

The study coupled gene therapy that excited visual neurons in the eyes with stimulation — a swirling black - and - white grid placed in front of the mice.

Both strains of mice were extremely fat, a trait that was passed on to their offspring in a simple, dominant pattern of inheritance, like eye color.

To figure out how the cells find their way from the eye to their final destination in the brain, Osterhout and her colleagues examined mice that had been bred to make green fluorescent protein, or GFP.

The largest effect was on the number of times the mice went in and out of a sleep phase called paradoxical sleep, which resembles REM (rapid eye movement) sleep in humans, when dreams occur and memories are strengthened.

They used this footage to draw up a «mouse grimace scale» based on changes in the face such as squinting eyes and bulging cheeks.

While investigating mouse eye cells, Botond Roska and his team at the Friedrich Miescher Institute for Biomedical Research in Basel, Switzerland, noticed that one type behaved unusually in response to movement.

By peering into the eyes of mice and tracking their ocular movements, researchers made an unexpected discovery: the visual cortex — a region of the brain known to process sensory information — plays a key role in promoting the plasticity of innate, spontaneous eye movements.

The mutation had blinded those mice with surgical precision, yet for reasons lost to history, Keeler got the strange idea to shine a light in their eyes anyway.

Scanziani and his colleagues sought to understand the origins of this adaptive plasticity by studying the eye movements in mice before and after disabling their vestibular ocular reflex.

Mice and humans are so closely related that it seemed likely we have the same basic collection of ipRGCs in our eyes, carrying out the same tasks.

When we took the mouse version of this gene — the same gene we find in the human — and put it in the fly and tweaked it, we induced fly eye tissue.

First she deprived juveniles of vision in one eye so that the corresponding brain cells failed to make connections; once the mice reached maturity, they were put in a water maze that required them to recognize a pattern of fine lines to find a floating platform.

They have also, in experiments with mice, been able to slow eye tumor growth with an existing FDA - approved drug.

Stevens and her colleagues manipulated mice to make one eye more active than the other, creating a disparity in activity between the two neural circuits linking the eyes to the brain.

These glowing layers reveal the complex structure of the retina — the photoreceptive part of the eye — in a mouse at one month old.

Many experiments later, Wang, Wong and colleagues have shown that tamoxifen, a drug used to treat breast cancer, can help preserve photoreceptors — and sight — in mice with eye injuries.

By pairing a receptor that targets neurons with a molecule that degrades the main component of Alzheimer's plaques, the biologists were able to substantially dissolve these plaques in mice brains and human brain tissue, offering a potential mechanism for treating the debilitating disease, as well as other conditions that involve either the brain or the eyes.

Now scientists at the Massachusetts Institute of Technology (MIT) have taken a first step toward designing such a treatment: They have identified a protein that stimulates regrowth of severed eye - brain connections in mice, according to a report in tomorrow's issue of Nature.

EYE CANDY Researchers grew primitive retinas (one shown, with proteins that collect and transmit light signals in green and red) by embedding mouse embryonic stem cells in a gel.

A newly developed user interface, the «i - Mouse,» in the K - Glass 2 tracks the user's gaze and connects the device to the Internet through blinking eyes such as winks.

The team found that, unlike control mice, which only undergo ocular dominance shifts if an eye is closed early in life, mice without Lynx1 still showed these shifts for eye manipulations well into adulthood.

The basic experimental approach is to record from neurons of the visual cortex of an animal - in this case a mouse - some time after one of its eyes has been sutured shut.

Testing their microparticles in mice, the team found that the drug persisted in their eyes for at least 14 weeks, more than three times as long as the current treatment.

In a four - year study conducted on the mouse model in advanced breast cancer metastasis in the eye's anterior chamber, Petty and colleagues found that the new nanoparticle not only killed tumor cells in the eye, but also extended the survival of experimental mice bearing 4T1 tumors, a cell line that is extremely difficult to kilIn a four - year study conducted on the mouse model in advanced breast cancer metastasis in the eye's anterior chamber, Petty and colleagues found that the new nanoparticle not only killed tumor cells in the eye, but also extended the survival of experimental mice bearing 4T1 tumors, a cell line that is extremely difficult to kilin advanced breast cancer metastasis in the eye's anterior chamber, Petty and colleagues found that the new nanoparticle not only killed tumor cells in the eye, but also extended the survival of experimental mice bearing 4T1 tumors, a cell line that is extremely difficult to kilin the eye's anterior chamber, Petty and colleagues found that the new nanoparticle not only killed tumor cells in the eye, but also extended the survival of experimental mice bearing 4T1 tumors, a cell line that is extremely difficult to kilin the eye, but also extended the survival of experimental mice bearing 4T1 tumors, a cell line that is extremely difficult to kill.

In addition to testing a new drug that effectively stops such runaway vessel growth in mice, the team gave the drug a biodegradable coating to keep it in the eye longeIn addition to testing a new drug that effectively stops such runaway vessel growth in mice, the team gave the drug a biodegradable coating to keep it in the eye longein mice, the team gave the drug a biodegradable coating to keep it in the eye longein the eye longer.

NERVE PROTECTORS The glowing cells in this micrograph of a mouse's optic nerve help shield electrical signals passing between eyes and brain.

In normal mice with working photoreceptors (PR driven), stimulating the retina produces a variety of responses in retinal ganglion cells, the output of the eyIn normal mice with working photoreceptors (PR driven), stimulating the retina produces a variety of responses in retinal ganglion cells, the output of the eyin retinal ganglion cells, the output of the eye.

In the SOD1 mouse, muscles that move the eye (left) retain nerve contacts and are active.

They found that the mice can develop damage to the optic nerve despite normal pressure in the eye following KPro surgery and identified TNFa and IL - 1 as inflammatory factors involved in this process, with high levels of TNFa mediating the damage to the optic nerve.

«We used a mouse model of the KPro to, first of all, identify the inflammatory factors that cause damage to the eye, and then we also quantified the amount of nerve cell death in the back of the eye that mediates the optic neuropathy, and, lastly, we looked at blocking these factors with antibodies,» said Reza Dana, M.D., M.Sc., MPH, Director of the Cornea and Refractive Surgery Service at Massachusetts Eye and Ear and the Claes H. Dohlman Professor of Ophthalmology at Harvard Medical School.

To precisely map how glucose and lactate move around in the eye, Hurley and colleagues grew human RPE in a lab dish and studied its biochemistry along with that of isolated mouse retinas.

Researchers from Massachusetts Eye and Ear / Harvard Medical School have identified inflammatory factors that cause optic neuropathy in the back of the eye following implantation of a keratoprosthesis (KPro)-- similar to what glaucoma patients experience, without the rise of pressure in the eye — and have shown that blocking one of those factors, tumor necrosis factor alpha (TNFa), successfully halts the development of optic nerve damage in a mouse model.

«Importantly, the investigation also demonstrates that newly generated cells in the mouse retina not only look and behave like neurons, they also wire correctly to the existing neural circuitry at the back of the eye.»

Working with mice, a multicenter team of researchers has found a new way to reduce the abnormal blood vessel growth and leakage in the eye that accompany some eye diseases.