Sentences with phrase «in mucins»

In a related series of experiments, the team found that the phages are studded with antibodylike molecules that grab onto the sugar chains in mucins.

It nicely illustrates how dynamic and quickly this responds to diet and bacterial alterations,» says Gunnar C. Hansson, a co-senior author with Bäckhed and a professor in the Mucin Biology Group at the University of Gothenburg, Sweden.

Thus, in the opinion of the scientists, it should be sufficient to soak the contact lenses overnight in a mucin solution to obtain the protective effect.

Colorectal cancer in mice genetically deficient in the mucin Muc2.

Tracing backward one step toward the source of mucin deficiency, the sugars in mucin are built from smaller pieces called O - glycans.

The role of calcium in mucin packaging within goblet cells.

Not exact matches

In addition, human milk contains large molecules called mucins that include a great deal of protein and carbohydrate.

Mucin, the major component of mucus, plays an important role in the clearance of bacterial pathogens, but uncontrolled, excessive mucus production can lead to conductive hearing loss and decreased bacterial clearance.

In a recent study published in the journal Advanced Materials Interfaces, the researchers show how mucins — the components that give mucus its structure — can lose their lubricative abilitIn a recent study published in the journal Advanced Materials Interfaces, the researchers show how mucins — the components that give mucus its structure — can lose their lubricative abilitin the journal Advanced Materials Interfaces, the researchers show how mucins — the components that give mucus its structure — can lose their lubricative ability.

Before it is ready for application in humans, the pig stomach mucin will undergo further testing in the lab.

Our tears contain such mucins, which also occur in the mucous layer protecting the stomach and intestines.

In collaboration with researchers at the Massachusetts Institute of Technology and Johnson & Johnson, the TUM team showed that if mucins lose these sugar molecules, they can no longer bind a sufficient amount of water, which causes them to lose their lubricative potential.

«Most of the commercially available mucins, which are already used e.g. for the treatment of oral dryness, have lost exactly this ability; we were able to demonstrate this in a series of experiments.

«In the future, the repair molecules could be applied through a spray or eye drops to regenerate the mucins directly on the mucus membranes.»

In experiments with porcine eyes they tested how their lab - isolated mucins affected the performance of contact lenses.

This, in turn, results in too much mucin being produced by the mucous membranes in the airways, restricting the flow of air and causing the shortness of breath felt during an asthma attack.

These range from those that are very similar to the acid - secreting glands of the stomach to those that look like intestinal crypts — indeed intestinalisation (defined by the presence of mucin secreting goblet cells), is diagnostic for Barrett's in some countries.

Behavior of the two novel mucins will be examined in cultured TM cells and in the TM of intact eyes using recombinant DNA, biochemical, and imaging techniques in order to provide clues to function.

The idea that mucins might be present in this lining layer and play a role in ocular hypertension has not been previously considered.

It is hypothesized that the novel mucins are part of a sugar - rich TM coating known as the glycocalyx, and that their altered production in response to steroids could lead to OH.

In this study, we explored the antitumor potential of prostate stem cell antigen (PSCA)- redirected CAR T and mucin 1 (MUC1)- redirected CAR T cells in tumor models of NSCLIn this study, we explored the antitumor potential of prostate stem cell antigen (PSCA)- redirected CAR T and mucin 1 (MUC1)- redirected CAR T cells in tumor models of NSCLin tumor models of NSCLC.

Aptamers targeted mucin - 1 (MUC1), a glycosylated surface protein overexpressed on many cancers, including MCF7 breast cancer cells, and only minimally expressed in MCF - 10A non-cancerous cells.

Whether it's Mizon's famed All - in - One Snail Cream incorporating ingredients like snail mucin to ampoules that include microneedles made of marine solids, Korean beauty innovates with unique ingredients you often won't find in other skin care.

The colonic mucus barrier is produced by specialized cells in our gut epithelium lining that secrete mucin.

Sulfate is essential for many biological processes, helping to flush toxins and helping form proteins in joints, brain tissue and mucin proteins.

Mucins, the most important molecules in mucus, tears, and saliva, are predominantly composed of carbohydrate.

The effect of diet on the gluconeogenic capacity of rat - kidney - cortex slices [5] Liver and kidney metabolism during prolonged starvation [6] Unrecognized Pandemic «Subclinical» Diabetes of the Affluent Nations: Causes, Cost and Prevention [7] Carbohydrates and Immune Function [8] Overexpression of glut1 and glut3 in stage I nonsmall cell lung carcinoma is Associated with poor survival [9] The in?uence of diet on the mucin carbohydrates in the chick intestinal tract [10] Rat intestinal mucosal responses to a microbial flora and different diets [12] Chronic Ethanol Induced Impairment of Hepatic Glycosylation Machinery in Rat Is Independent of Dietary Carbohydrate [13] Glycosylation in Cellular Mechanisms of Health and Disease [14] Metabolic Aberrations Associated with Arginine Deficiency [15] Glycerol gluconeogenesis in fasting humans

A third factor to consider is that the gut, due to its mucin production, immune activity, and rapid turnover in cells and extracellular matrix, is a major consumer of glucose.

Do not forget that mucin is a glycoprotein rich in mentioned amino acids.

This happens because mucin - 2, the primary constituent of mucus in the gut, is 80 % carbohydrate, and when the body is carb - starved glucose is triaged for the benefit of the brain, starving other tissues like the gut.

A personal favorite is, Role of endogenous microbiota, probiotics and their biological products in human health, which has a TON of probiotic human health technical ramifications including mucin layer expression, TJs, immunity... Many of the probiotics discussed are in fermented vegetables; recall yogurt, even SCD yogurt, has a limited number of strains, perhaps only three.

But even prior to all this, we had severe concerns about VLC / ketogenic diets: the very low triglycerides that these ketogenic dieters attain were being implicated in autoimmune pathogenesis in an Italian study; the mucin deficiency that you mention were also being linked to immune (Secretory IgA deficiency); the T - lymphocyte dysfunction was being linked to ketosis and its effect on thymus; and the general leukopenic effect that a VLC diet has on everyone — this was being attributed to inflammation reduction but we were seeing WBCs fall into the 2s in many people.

In addition, the host itself produces substrates such as glycoproteins (e.g., mucins) which contribute to the available amino acids within the colon [39].»

As the rules / tenants of basic microbial ecology go, a reduction in fermentable substrates derived from carbohydrates means less energy sources for the microbes — who depend on host - derived substrates as well, as in the case of mucin - degraders like Akkermansia.

Muc1 cell surface mucin attenuates epithelial inflammation in response to a common mucosal pathogen.

Some micronutrients are required for mucin production — notably vitamin D. [7, 8] Poland is fairly far north, and many of the Optimal Dieters could have been low in vitamin D.

Don't worry — the 96 percent snail mucin in this essence isn't the same slime you'd get from a sidewalk snail; it's a processed, cosmetically elegant version that's collected from edible snails.

I think I freaked a couple people out from it, but ifff you can get past the fact that there's snail mucin in the product, it's legit one of my favorite moisturizers out there!

They are actually always there but as the animal gets older they become less efficient at producing IgA and mucin in the digestive tract.

Other common masses are lipomas or fatty growths and «mucinomas» or localized accumulations of mucin in the skin which can appear as tumors.

The hair follicles may also be spread apart by the accumulation of mucin in these areas resulting in less coat coverage.