Smith MR, Syed A, Lukacsovich T, Purcell J, Barbaro BA, Worthge SA, Wei SR, Pollio G, Magnoni L, Scali C, Massai L, Franceschini D, Camarri M, Gianfriddo M, Diodato E, Thomas R, Gokce O, Tabrizi SJ, Caricasole A, Landwehrmeyer B, Menalled L, Murphy C, Ramboz S, Luthi CR, Westerberg G, Marsh JL.A potent and selective Sirtuin 1 inhibitor alleviates pathology
in multiple animal and cell models of Huntington's disease..
After all, he says,
in multiple animal species «learning has long been associated with a reduction in stress.»
«We found that AIM2 inhibits tumorigenesis
in multiple animal models of colorectal cancer by restricting the pro-survival signaling molecule, Akt, which is commonly hyperactive in many human cancers.»
The model is the first to focus on how and why home ranges expand or contract in territorial animals, a trend noted
in multiple animals ranging from deer and pandas to owls and flying lizards.
Not exact matches
There are no chestnuts on Chestnut Lane, no elms on Elm Street, no caribou
in Caribou, Maine, and no buffalo
in Buffalo, N.Y.
Multiple states have had to change their official tree,
animal or flower because of extinctions.
The ethics of authorship, obligation to cite prior work, and problems of
multiple authorship have been analyzed
in an article
in Science.13 Others have been concerned about the humane treatment of
animals, which are crucial
in experimental biology and pharmacology.
Recent and upcoming releases include the romance - horror hybrid Spring; the hotly - anticipated The Look Of Silence, Oppenheimer's companion piece to The Act Of Killing; The Connection, a 70's - set true crime epic and European flipside to William Friedkin's The French Connection starring Oscar ® winning Best Actor Jean Dujardin (The Artist); The Keeping Room, from director Daniel Barber (Harry Brown), based on Julia Hart's acclaimed Black List screenplay, starring Brit Marling, Hailee Steinfeld and Sam Worthington; the
multiple Cannes award winning The Tribe, filmed entirely
in Ukrainian Sign Language with a cast of deaf, non-professional actors; and a remastered re-release,
in conjunction with Olive Films, of the 1981 disasterpiece Roar, the most dangerous film ever made, starring Tippi Hedren, Melanie Griffith and a cast of 150 untrained lions, tigers and exotic
animals.
«Most of the identified incidents involved
multiple animals, up to several thousand
in one instance.
The oil is also used
in animal feed, and while major global retail chains,
multiples and manufacturers such as Arla, Danone, Kelloggs, M&S and Unilever have already begun to show their support for sustainable palm oil products, the agriculture industry has been slower to catch on.
Folded
in almost as many styles as origami
animals, they offer
multiple ways to suit babies of all sizes.
Animals in nature benefit from having
multiple sexual partners.
With the Niteangel Natural Living Tunnel System for small
animals, your creatures will have
multiple places to explore
in an all - natural setting.
Here are some of the excluding criteria most experts agree on: «Obese parents; parents who smoke (either during pregnancy or at present); parents sleeping on a waterbed, recliner, sofa, armchair, couch or bean bag; parents who sleep on
multiple pillows, a sagging mattress or a sheepskin or use heavy bedding, such as comforters or duvets; sleeping
in overheated rooms; parents under the influence of drugs or alcohol; other children or pets who can or are likely to climb into the bed; and stuffed
animals on the bed that could cover the baby's face.»
-------- *** NOTE: NEVER APPLY THESE TO AN
ANIMAL THAT GO OUTDOORS OR THEY CAN NOT DEFEND THEMSELVES IF THEY GET
IN A FIGHT ***** They come in multiple sizes and can be available in multiple color
IN A FIGHT ***** They come
in multiple sizes and can be available in multiple color
in multiple sizes and can be available
in multiple color
in multiple colors.
It has a jungle theme and is designed
in multiple shades of green with colorful
animals attached to its perimeter.
Oneida County Youth Bureau Director Robert Roth said youth volunteers from The Boys and Girls Club of the Mohawk Valley, Compeer of the Mohawk Valley, Cornell Cooperative Extension, The Center for Family Life and Recovery, The Neighborhood Center, Thea Bowman House, Utica Municipal Housing Authority, Utica Safe Schools / Healthy Students / Underground Café and the YMCA of the Greater Tri-Valley performed community service that included assisting
in a bicycle giveaway program for Utica children, collecting and distributing clothing to the children who reside
in Utica's Municipal Housing Authority locations, soliciting donations, collecting money and walking
in Utica's version of America's Greatest Heart Run and Walk, the
Multiple Sclerosis Walk and the American Cancer Walk, collecting food, preparing and serving meals at local food pantries, collecting donations and goods to aid
animals at the Stevens Swan Humane Society and other community activities.
The CambelBak Eddy Water Bottles are available
in a range of different colors and
animal patterns that will definitely make them cool water bottles for kids without having to worry about the same one for
multiple children.
In the lab, researchers will try to re-create the Thai results in monkeys to validate a new animal model using multiple low dose
In the lab, researchers will try to re-create the Thai results
in monkeys to validate a new animal model using multiple low dose
in monkeys to validate a new
animal model using
multiple low doses.
«Much like the spread of human disease
in populated areas, urban centers can foster increases
in multiple disease types
in wild
animals,» said McGraw, senior author of the study.
The U.N. declaration calls for action on
multiple fronts, including slashing the use of antibiotics to promote growth
in farm
animals, limiting their use among humans to only when they are truly necessary and ramping up education about these issues.
These chips are important for eliminating many early problematic amalgams, but
animal tests are still needed to see how a drug is broken down by
multiple organs
in the body — the liver and gut,
in particular — and how the broken - down metabolites circulate to other organs, the 29 - year - old San Jose, Calif., native says.
To be sure, other researchers have looked for Ebola
in the forest here, sampling many
animals in multiple locations.
Understanding the mechanisms that drive migratory behavior is increasingly important, Beck said,
in terms of climate change, as migrating
animals rely on
multiple habitats.
So the natural extension of this paper's line of inquiry is how the positive and negative systems associated with cocaine use change when
animals are exposed to
multiple doses
in any given day (i.e. addiction).
In a paper published online this week in Animal Behaviour, Shaw and her colleagues report wide variations in how well the birds did on multiple trials of each tes
In a paper published online this week
in Animal Behaviour, Shaw and her colleagues report wide variations in how well the birds did on multiple trials of each tes
in Animal Behaviour, Shaw and her colleagues report wide variations
in how well the birds did on multiple trials of each tes
in how well the birds did on
multiple trials of each test.
Testicles are almost always bigger
in animal species
in which females mate with
multiple partners, says Scott Pitnick, an evolutionary biologist at Syracuse University.
Whether
animals could be used for
multiple experiments was also an issue largely resolved
in the favor of scientists.
His laboratory already has shown that by inhibiting calcium channels
in T - cells, they were able to prevent T - cell activation
in animal models of autoimmune diseases like
multiple sclerosis and colitis.
In this episode, Scientific American news editor Phil Yam discusses how veterinarians, physicians and multinational food companies need to work together in the global fight against animal - borne infectious diseases; and University of Wisconsin evolutionary biologist Sean Carroll talks about recent research tracking the evolution of yeast genes with specific functions descended from a single, duplicated gene with multiple function
In this episode, Scientific American news editor Phil Yam discusses how veterinarians, physicians and multinational food companies need to work together
in the global fight against animal - borne infectious diseases; and University of Wisconsin evolutionary biologist Sean Carroll talks about recent research tracking the evolution of yeast genes with specific functions descended from a single, duplicated gene with multiple function
in the global fight against
animal - borne infectious diseases; and University of Wisconsin evolutionary biologist Sean Carroll talks about recent research tracking the evolution of yeast genes with specific functions descended from a single, duplicated gene with
multiple functions.
Thanks to the genome sequencing of
multiple contemporary
animals of the deuterostome group, we can go back
in time to unveil aspects of the long - lost ancestor of this diverse group of
animals.
An FDA - approved drug for high blood pressure, guanabenz, prevents myelin loss and alleviates clinical symptoms of
multiple sclerosis (MS)
in animal models, according to a new study.
«Blood pressure drug protects against symptoms of
multiple sclerosis
in animal models.»
«
In less than a year, our group and others have demonstrated that multiple vaccine platforms can provide robust protection against Zika virus challenge in animal model
In less than a year, our group and others have demonstrated that
multiple vaccine platforms can provide robust protection against Zika virus challenge
in animal model
in animal models.
The
animals, which stand head and
multiple shoulders above other invertebrates
in terms of intelligence, grow to 45 kilograms and typically measure around 4 metres from arm tip to tip.
The researchers then tested the capacity of the modified cells to kill human
multiple myeloma cells
in laboratory studies and an
animal model.
Across
multiple triple - negative breast cancer subtypes, inhibiting the androgen receptor greatly increased apoptosis (programmed cell death), inhibited growth and increased necrosis by 60 percent
in animal models.
The findings thus support the idea that SSB may be prevalent
in one sex because the genes regulating the behaviour are preserved by natural selection through their benefits
in the opposite sex, pointing to a general mechanism maintaining
multiple forms of SSB across a wide variety of
animals.
Newbury,
in collaboration with Kathy Toohey - Kurth, virology section head at the Wisconsin Veterinary Diagnostic Laboratory, recently tested
multiple cats at an
animal shelter
in Northwest Indiana and found them positive for the H3N2 canine influenza virus.
But with no evidence of a large asymptomatic population so far, Kellam and his colleagues favor a second scenario: MERS evolved and diversified
in animals and then infected humans on
multiple occasions.
Though researchers knew that switchgrass and other perennial grasses have certain advantages over maize, the study is the first to look at
multiple ecosystem services and
animal populations at the same time, says Silvia Secchi, an agribusiness economist at Southern Illinois University
in Carbondale.
Isolates of a common poultry pathogen collected from
animals in Indian bird markets were mostly resistant to
multiple classes of antibiotics.
The prize is for discovering «the brain's navigation system»: place cells, cells
in the hippocampus which are active whenever a rat is
in a particular place, and grid cells, cells
in the entorhinal cortex which are active when the
animal is at
multiple locations
in a grid pattern.
Despite reduced levels of mRNA expression, the homozygous lethal Xpd † XPCS allele ameliorated
multiple XpdTTD - associated disease symptoms
in compound heterozygous XpdTTD / † XPCS
animals including the hallmark brittle hair and cutaneous features fully penetrant
in homo - and hemizygous TTD mice (Figure 2A — 2C).
Our work
in the lowly roundworm will shed light on how the nervous system processes information over
multiple timescales with relevance for larger
animals, including humans.
This
animal model closely resembles lesion kinetics as seen
in human disease [34] and use of non-human primates allows for repetitive surgical sampling for
multiple time point analysis.
Katherine W. Klinger, PhD, Senior Vice President for Genetics and Genomics at the Genzyme Corporation, and Assistant Clinical Professor
in the Department of Pediatrics at the University of Connecticut School of Medicine suggested that for an orphan disease it may be necessary to use
multiple animal models
in the preclinical research stage, because one
animal model may not fully recapitulate the human disease.
The cross-license enables Caribou to develop and utilize CRISPR - Cas technology for product development
in multiple fields including human and
animal therapeutics, diagnostics, industrial biotechnology, research tools, and certain agriculture segments.
Animal gait is affected
in models of human disorders such as Parkinson's Disease,
Multiple Sclerosis, Amyotrophic Lateral Sclerosis, spinal cord injury and many others.
An
animal model of cortical and callosal pathology
in multiple sclerosis.
In both humans and
animals,
multiple brain regions have been proposed to contribute to depression, and understanding which of these regions is dysfunctional might let us treat it better.