Sentences with phrase «in multiple cancer types»

We validated ZBTB20, CELF2, PARD3, AKAP13 and WAC, which were identified by our screens in multiple cancer types, as new tumor suppressor genes in prostate cancer.

We identified known and putative TSGs in multiple cancer types and validated the functional and clinical relevance of several promising candidates for human prostate cancer.

The platform contains over 10,000 somatic variants curated for oncogenicity, 100 genes curated for druggability in multiple cancer types and 500 drugs curated for evidence in multiple cancer types.

«Nutrient scavenging by autophagy is a process that tumors hijack to meet their energetic requirements and to provide the necessary cellular building blocks for growth in a stressed tumor micro-environment» said White, «Preclinical models have demonstrated a critical role for autophagy in multiple cancer types.»

Clinical trials are currently trying to do just this in multiple cancer types, but this is the first study that has shown that it might also work for colon cancer.

BETs have been fast - tracked into clinical trials and have shown impressive slowing of tumor growth in multiple cancer types.

Physical activity reduces risk of cancer development in multiple cancer types including lung.

AA is implicated in multiple cancer types, sometimes with very high mutational burdens, especially in upper tract urothelial cancers (UTUCs).

«We remain committed to advancing our IDO pathway inhibitor indoximod, which continues to generate exciting data in combination with anti-PD-1 agents, cancer vaccines, and chemotherapy in multiple cancer types including melanoma, prostate cancer, acute myeloid leukemia, and pancreatic cancer.»

Not exact matches

«Opdivo has become a foundational treatment that is transforming cancer care across multiple tumor types,» chief executive Giovanni Caforio said in a statement.

The two companies plan to develop drugs to fight multiple cancer types, either alone or in combination with their other cancer treatments.

The drug already has undergone initial testing in more than 550 patients with multiple types of cancer.

In July the FDA approved Onyx's Kyprolis as a treatment for multiple myeloma, a type of blood cancer.

Breech Twins and higher order multiples Previous CS Pre-Eclampsia Placenta praevia Cervical incompetence Previous late stillbirth Previous premature birth Grand multiparty Age under 18 Age over 35 Smoking Drug use Severe mental health issue Epilepsy Type 1 diabetes Type 2 diabetes Gestational diabetes Asthma GBS positive Abnormal antibodies Transplant recipient Congenital heart disease Known foetal abnormality Immunosuppressive medication MS Physical disability Intellectual disability Hypothyroidism Hyperthyroidism Previous shoulder dystocia Previous 3rd or 4th degree tear Sickle Cell anaemia BMI under 18 or over 35 at conception Previous massive PPH APH in current pregnancy HIV / AIDS Hepatitis B or C Active TB IUGR Oligohydramnios Polyhydramnios Child previously removed from custody because of abuse Uterine abnormalities such as uterine septum or double uterus Previous uterine surgery for fibroids Chronic renal problems Hypertension Auto immune condition Previous stroke or blod clot Cancer Domestic violence or abusive home Prisoners Homeless women

(borrowed from Dr Kitty) Breech Twins and higher order multiples Previous CS Pre-Eclampsia Placenta praevia Cervical incompetence Previous late stillbirth Previous premature birth Grand multiparty Age under 18 Age over 35 Smoking Drug use Severe mental health issue Epilepsy Type 1 diabetes Type 2 diabetes Gestational diabetes Asthma GBS positive Abnormal antibodies Transplant recipient Congenital heart disease Known foetal abnormality Immunosuppressive medication MS Physical disability Intellectual disability Hypothyroidism Hyperthyroidism Previous shoulder dystocia Previous 3rd or 4th degree tear Sickle Cell anaemia BMI under 18 or over 35 at conception Previous massive PPH APH in current pregnancy HIV / AIDS Hepatitis B or C Active TB IUGR Oligohydramnios Polyhydramnios Child previously removed from custody because of abuse Uterine abnormalities such as uterine septum or double uterus Previous uterine surgery for fibroids Chronic renal problems Hypertension Auto immune condition Previous stroke or blod clot Cancer Domestic violence or abusive home Prisoners Homeless women

They also pointed to a 2013 study that showed elevations in multiple types of cancers in Tonawanda, Erie County, where residents have expressed concerns about air emissions from various industries.

He and his colleagues are now investigating how gene profiles are altered and whether these techniques could ease symptoms in people with high blood pressure, inflammatory bowel disease and multiple myeloma, a type of bone marrow cancer.

The nanoparticles carry a drug compound that blocks a protein called Myc that is active in many types of cancer, including multiple myeloma.

Whether investigating fat cells, immunotherapy or use of the CRISPR - Cas 9 gene - editing tool, which a federal panel recently approved for a select number of patients suffering from three types of cancers, including multiple myeloma, approaches beyond attacking cancer cells are needed in the fight against many cancers.

Rewinding skin cells back to their origins in the womb could provide a powerful new vaccine against multiple types of cancer.

The authors showed that the use of this drug remains widespread in Asia and particularly in Taiwan, and that it appears to increase the risk of multiple different cancer types.

Published October 29, 2015 in the journal Science, the new results lend insights into potential mechanisms of chronic itch, which is caused by a variety of conditions such as eczema, diabetic neuropathy, multiple sclerosis and certain types of cancers.

While multiple imaging techniques, including MRI, are currently used in breast cancer detection and clinical management, they are neither able to detect specific cancer types or early cancer growth.

«Multiple epigenetic regulators participate in the drug - desensitizing pathway, so they could serve as new targets to improve therapy for this type of cancer.»

Dor's own group reports this week that its technique for tracing the origin of circulating DNA detected the expected type of cell death in people with pancreatic cancer, type 1 diabetes, multiple sclerosis, and brain injuries.

Multiple myeloma is the second most common type of blood cancer in the United States, after lymphoma and leukemia.

Researchers from Uppsala University, Sweden, and the Broad Institute, USA, have identified both similarities and differences between a single tumor type in multiple dogs breeds; a finding they believe parallels the situation in the cancer of human patients.

Multiple myeloma is a blood cancer that forms in a type of white blood cell called a plasma cell.

The THC and cannabidiol studies will be extended to include chronic types of pain typically seen in people who request medical marijuana — such as those with debilitating back or joint pain, cancer, Crohn's disease, multiple sclerosis, severe muscle spasms and more.

Cancer cells resemble stem cells not because they can turn into other cell types, but because in developmental terms, they seem to go in the opposite direction: they begin to run through multiple layers of stop signs and barricades and just keep on multiplying.

«Our prototype drug works in multiple types of cancers and encourages us that this could be a more general addition to the cancer drug arsenal.»

Researchers from Uppsala University, Sweden, and the Broad Institute, USA, have identified both similarities and differences between a single tumour type in multiple dogs breeds; a finding they believe parallels the situation in the cancer of human patients.

Multiple bubbles of the same color represent multiple cancer types that are being tested in theseMultiple bubbles of the same color represent multiple cancer types that are being tested in thesemultiple cancer types that are being tested in these trials.

Notably, we studied the feasibility for enrichment of ctDNA by physical and in silico size selection in plasma samples collected in 51 patients from multiple cancer types.

The first step was when she noticed several papers that contained a mistake in a DNA construct which, she believed, meant the papers were not testing the gene in question, associated with multiple cancer types.

Myeloma — also referred to as multiple myeloma or plasma cell myeloma — is a cancer that originates in plasma cells, a type of white blood cell that makes antibodies.

Multiple myeloma is one of the major cancer types for which new immune - based cancer treatments are currently in development.

Melanoma was another cancer type surveyed by multiple exome sequencing studies in 2011.

Myeloma — also referred to as multiple myeloma or plasma cell myeloma — is a cancer that originates in plasma cells, a type of white blood cell that make antibodies.

Researchers from SciLifeLab / Uppsala University, Sweden, and the Broad Institute, USA, have identified both similarities and differences between a single tumour type in multiple dogs breeds; a finding they believe parallels the situation in the cancer of human patients.

My studies of cancer genomes have led to characterization of multiple pediatric and adult tumor types, to development of methods that identify and characterize changes in genomic heterogeneity, to defining acquired resistance mechanisms to targeted therapies and to designing novel, personalized vaccines for individual patients.

February 10, 2015 New screening tool could speed development of ovarian cancer drugs University of Chicago Medicine researchers have built a model system that uses multiple cell types from patients to rapidly test compounds that could block the early steps in ovarian cancer metastasis.

In addition, because ZVex product candidates have the potential to carry the genetic material of different tumor antigens, as well as immunostimulatory molecules, we can design them to target multiple types of cancers.

University of Chicago Medicine researchers have built a model system that uses multiple cell types from patients to rapidly test compounds that could block the early steps in ovarian cancer metastasis.

Hereditary cancer syndromes are caused by variants in genes that control cell growth in multiple tissue types.

Recent research has provided major breakthroughs in this field, resulting with some strong indicators that the blood type can be a key influence in multiple aspects of the health, from infertility to an increased risk of cancer.

If you are a stranger to that and as to why you need and want carotenoids (generally, you are likely deficient in them, they have antioxidant effects scavenging and quenching free radicals, and they are associated with reduced risk of a variety of common diseases including multiple types of cancer including breast cancer) read the post, MEET THE FATS & BEST SALAD DRESSING OIL, PART1.

Melatonin is important for the proper functioning of your immune system, scavenging free radicals, reducing inflammation, and helping your body to rid itself of cancer cells; multiple studies point to the role of melatonin in protecting you from multiple types of cancer, including breast cancer

In the early days of starting my nutrition counseling practice, my dad was diagnosed with multiple myeloma, an incurable type of blood cancer.

There are multiple types of bladder cancers, some start out in the bladder, while others may have metastasized to the bladder.