Several regions identified
in myelin basic protein and P2 protein can be related to experimental allergic encephalomyelitis or neuritis in laboratory animals.
Not exact matches
The researchers tested these cells on a batch of mice that had been injected with
myelin basic protein, which triggers the autoimmune response and causes EAE symptoms to occur
in about 2 weeks.
Modulation of Canonical Transient Receptor Potential Channel 1
in the Proliferation of Oligodendrocyte Precursor Cells by the Golli Products of the
Myelin Basic Protein Gene.
Proline substitutions and threonine pseudophosphorylation of the SH3 ligand of 18.5 - kDa
myelin basic protein decrease its affinity for the Fyn - SH3 domain and alter process development and
protein localization
in oligodendrocytes.
Host: Dr. Alex MacKay Speaker: Dr. George Harauz, Univ. of Guelph Title: Myel - Stones or The Executive Roles of
Myelin Basic Protein in Myelin Assembly and Destabilization
in Multiple Sclerosis
The pathogenesis of this appears to be based on an immunological reaction against the
basic protein in myelin that is triggered by the distemper virus.