In some narcoleptics, strong emotions can trigger a sudden loss of muscle tone, called cataplexy, that leaves them lying on the floor, body limp and paralyzed but with their minds perfectly awake.
Why powerful feelings can trigger cataplexy
in some narcoleptics is not well understood.
Further sleuthing revealed that the cells that normally produce it in the brain seem to have been destroyed
in narcoleptics.
In narcoleptics, however, rem sleep arrives out of order.
Mignot and his colleagues have begun population studies to see whether hypocretin receptor 2 mutations appear
in narcoleptic people.
The discovery of an abnormal gene
in narcoleptic pooches may soon lead to relief for millions of people who suffer from chronic insomnia.
The challenge is to discover how the mechanism breaks down
in narcoleptic humans and then to develop drugs that correct it.
In narcoleptic patients, the mechanism that makes the hormone is intact, but the cells are missing, suggesting that something destroys them.
I would spend my days
in a narcoleptic daze.
[Kit Harington's] a narcotized Jon Snow
in a narcoleptic of a miniseries that nods off at times, and seems maddeningly unaware that viewers will be induced to do the same thing.
Not exact matches
In an election year when reality seems as remote as a Pluto flyby; a year already marked by bombastic promises of walls, jobs, «a future to believe in» and free stuff for everybody, maybe we should take a quick break from the narcoleptic snooze imposed on us by the mass medi
In an election year when reality seems as remote as a Pluto flyby; a year already marked by bombastic promises of walls, jobs, «a future to believe
in» and free stuff for everybody, maybe we should take a quick break from the narcoleptic snooze imposed on us by the mass medi
in» and free stuff for everybody, maybe we should take a quick break from the
narcoleptic snooze imposed on us by the mass media.
A
narcoleptic, Nicole has had a difficult time on tour, with only one top 10
in seven seasons, but I still think she has the goods.
Narcoleptics spontaneously fall asleep, often at inopportune moments — even while laughing at a joke, or
in the middle of an angry outburst.
Narcoleptics get a normal amount of sleep
in a 24 - hour period; it just happens to be broken into uncontrollable and disabling pieces.
In their private lives, many narcoleptics face unhappy choices: Do I sit in the dark, or risk climbing a high ladder to change the burned - out bulb and maybe have an attack and fal
In their private lives, many
narcoleptics face unhappy choices: Do I sit
in the dark, or risk climbing a high ladder to change the burned - out bulb and maybe have an attack and fal
in the dark, or risk climbing a high ladder to change the burned - out bulb and maybe have an attack and fall?
Yes,
narcoleptics have fallen asleep
in their spaghetti, but they have also caused serious auto wrecks.
He came to the United States
in 1986 to test a French narcolepsy drug on the Stanford sleep center's colony of
narcoleptic dogs, mostly Doberman pinschers and a handful of Labrador retrievers and dachshunds bred for the disorder.
Stimulants and other drugs such as modafinil are often very effective
in helping
narcoleptics fend off sleepiness during the day.
Because their sleep at night is disjointed and marked by frequent awakenings,
narcoleptics tend to be exhausted during the day, increasing their propensity for nodding off, even while
in the middle of doing something else.
The result indicates that T cells and HLA, which together regulate much of the body's immune response, gang up
in a unique way to destroy
narcoleptics» hypocretin cells, the team reports online this week
in Nature Genetics.
They found that the
narcoleptics in the study shared a version of another gene that tells T cells — the immune cells that destroy intruders — how to react to the pathogens that HLA molecules bring them.
In the late 1990s, his team discovered that
narcoleptics lack hypocretin, a hormone produced by a few brain cells that helps keep people and animals awake.
In their search for such a trigger in people who had become narcoleptic, Mignot's group found elevated levels of antibodies to Streptococcus pyogenes, a bacterium that causes strep throat and has been implicated in other autoimmune diseases, such as rheumatic feve
In their search for such a trigger
in people who had become narcoleptic, Mignot's group found elevated levels of antibodies to Streptococcus pyogenes, a bacterium that causes strep throat and has been implicated in other autoimmune diseases, such as rheumatic feve
in people who had become
narcoleptic, Mignot's group found elevated levels of antibodies to Streptococcus pyogenes, a bacterium that causes strep throat and has been implicated
in other autoimmune diseases, such as rheumatic feve
in other autoimmune diseases, such as rheumatic fever.
There's a built -
in joke about a support group for
narcoleptics and I'm not quite mentally ready to attend a meeting.
Compare it to the same year's
narcoleptic, madly - overpraised, utterly irrelevant Butch Cassidy and the Sundance Kid (which also ends
in a literal Mexican stand - off, as it happens) for a succinct précis of the wide gulf between what's popular and what's good.
Gus Van Sant's moody, Shakespeare - inflected street - youth tale follows a
narcoleptic hustler (River Phoenix) on a tragic journey
in search of himself.
My Own Private Idaho — Shakespeare's Henry IV, set among male prostitutes
in Portland with Keanu Reeves
in the Prince Hal role and River Phoenix as the
narcoleptic who's
in love with him.
In «Z.Z.'s Sleepaway Camp for Disordered Dreamers,» a boy whose dreams foretell implacable tragedies is sent to a summer camp for troubled sleepers (Cabin 1,
Narcoleptics; Cabin 2, Sleep Apneics; Cabin 3, Somnambulists...).
To celebrate, BANDAI NAMCO released the first gameplay trailer for Eliza, the devilish (seemingly
narcoleptic) vampire girl who first appeared
in Tekken Revolution.
Bubbly Lucky Chloe dances to the stage to annoy those she fells
in oline games and lovely (and
narcoleptic) vampire girl Eliza makes a welcome comeback from Tekken Revolution for pre-orderers.
Back to Bed (Bedtime Digital Games, $ 9.99)-- A 3D indie puzzle game set
in a unique artistic dream world, Back to Bed has players guiding the
narcoleptic sleepwalker Bob to the safety of his bed under the guise of his subconscious guardian, Subob.