Sentences with phrase «in nuclear reprogramming»

Elucidating the role of telomerase and telomeres in adult stem cell biology and in nuclear reprogramming of differentiated cells to iPS cells.

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In this study, partial reprogramming of cells in vitro reduced DNA damage accumulation and restored nuclear structurIn this study, partial reprogramming of cells in vitro reduced DNA damage accumulation and restored nuclear structurin vitro reduced DNA damage accumulation and restored nuclear structure.
After he got his doctorate in 2003, Hochedlinger decided to stay in Jaenisch's lab because he felt it was the best place to «really learn the most about reprogramming and nuclear cloning,» he says.
Nuclear reprogramming describes a switch in gene expression of one kind of cell to that of another unrelated cell type.
«Dolly the Sheep told me that nuclear reprogramming is possible even in mammalian cells and encouraged me to start my own project, wrote Yamanaka, who splits his time between the University of California, San Francisco, and the Center for iPS Cell Research and Application (CiRA) at Kyoto University in Japan, which he directs.
«Nuclear Reprogramming in Cells,» by J.B. Gurdon and D.A. Melton, Science, Dec. 19, 2008.
Topics covered include embryonic stem cells, pluripotency, germline stem cells, tissue - specific stem cells, stem cell differentiation, epigenetics, stem cell genomics and systems biology, genome reprogramming, cancer stem cells, stem cell niches, stem - cell - based disease models, nuclear transfer technology, bioengineering, drug discovery, in vivo imaging of stem cells, therapeutic applications, regenerative medicine, clinical and translational insights, stem cell research policies, ethical issues, and technical or resource - based innovations.
The Cas9 / gRNA - modified fibroblasts were subjected to nuclear reprogramming by somatic cell nuclear transfer, resulting in live - born goats carrying single - gene mutation.
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