Her first major discovery, in 2006, identified a loop
in the nucleoprotein of the H1N1 human influenza virus.
MxA is therefore a barrier against cross-species influenza A infection, but one that the virus can evade through a few mutations
in its nucleoprotein.
MxA is thought to target influenza A by binding to the nucleoprotein that encapsulates the virus» genome, and mutations
in this nucleoprotein have been linked to the virus» ability to infect human cells.
The combination of high crosslinking yields, excellent specificity, and elimination of photodamage to other chromophores represents an important advance toward the precise identification of contacts
in nucleoprotein complexes.
Not exact matches
Working
in the lab of biochemist and Nobel laureate Edward Tatum, Finch attempted to isolate
nucleoproteins from the bread mold Neurospora.
In December, Outi Vaarala of the University of Helsinki and her colleagues had reported that Pandemrix contained a much higher level of
nucleoprotein than a GSK vaccine called Arepanrix, which was associated with a much smaller risk for narcolepsy.
Their search turned up a suspect: a piece of a receptor for hypocretin resembles part of the H1N1 influenza
nucleoprotein — which binds to the virus genome and plays a key role
in its replication.
The mouse is described
in a study, «In vivo evasion of MxA by avian influenza viruses requires human signature in the viral nucleoprotein,» that will be published April 10 in The Journal of Experimental Medicin
in a study, «
In vivo evasion of MxA by avian influenza viruses requires human signature in the viral nucleoprotein,» that will be published April 10 in The Journal of Experimental Medicin
In vivo evasion of MxA by avian influenza viruses requires human signature
in the viral nucleoprotein,» that will be published April 10 in The Journal of Experimental Medicin
in the viral
nucleoprotein,» that will be published April 10
in The Journal of Experimental Medicin
in The Journal of Experimental Medicine.
Immunohistochemical staining of the tissues was carried out for the influenza
nucleoprotein detection
in sparrows» tissues.