Sentences with phrase «in on different factors»

So while there are «as many as three thousand different factors that can come into play when trying to understand the causes and consequences of obesity... individual experts tend to focus on just one or two of them, with different experts zeroing in on different factors.»

Not exact matches

When the company auctions that oilfield drill, for example, the goal is for its pricing model to forecast demand in the near future based on different factors, such as the price of oil, leaving Ritchie Bros. less vulnerable to market surprises.

Constantly working in a global context, it was important from quite early on to learn to work with the more challenging elements of different cultures, while at the same time identifying their best factors and making them my own.

These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.

These factors made our experience and initial cost to invest in the franchise much different than new franchisees; however a ballpark estimation would be $ 200,000 cash and a $ 500,000 SBA loan ($ 340,000 on construction, $ 325,000 on FF&E, $ 65,000 toward soft costs and $ 10,000 toward marketing efforts).

Customers buy from companies make their purchasing decisions based on many different factors, but one of those things is trust, which can be hard to put in a new company that does not have much information out on them.

Actual results, including with respect to our targets and prospects, could differ materially due to a number of factors, including the risk that we may not obtain sufficient orders to achieve our targeted revenues; price competition in key markets; the risk that we or our channel partners are not able to develop and expand customer bases and accurately anticipate demand from end customers, which can result in increased inventory and reduced orders as we experience wide fluctuations in supply and demand; the risk that our commercial Lighting Products results will continue to suffer if new issues arise regarding issues related to product quality for this business; the risk that we may experience production difficulties that preclude us from shipping sufficient quantities to meet customer orders or that result in higher production costs and lower margins; our ability to lower costs; the risk that our results will suffer if we are unable to balance fluctuations in customer demand and capacity, including bringing on additional capacity on a timely basis to meet customer demand; the risk that longer manufacturing lead times may cause customers to fulfill their orders with a competitor's products instead; the risk that the economic and political uncertainty caused by the proposed tariffs by the United States on Chinese goods, and any corresponding Chinese tariffs in response, may negatively impact demand for our products; product mix; risks associated with the ramp - up of production of our new products, and our entry into new business channels different from those in which we have historically operated; the risk that customers do not maintain their favorable perception of our brand and products, resulting in lower demand for our products; the risk that our products fail to perform or fail to meet customer requirements or expectations, resulting in significant additional costs, including costs associated with warranty returns or the potential recall of our products; ongoing uncertainty in global economic conditions, infrastructure development or customer demand that could negatively affect product demand, collectability of receivables and other related matters as consumers and businesses may defer purchases or payments, or default on payments; risks resulting from the concentration of our business among few customers, including the risk that customers may reduce or cancel orders or fail to honor purchase commitments; the risk that we are not able to enter into acceptable contractual arrangements with the significant customers of the acquired Infineon RF Power business or otherwise not fully realize anticipated benefits of the transaction; the risk that retail customers may alter promotional pricing, increase promotion of a competitor's products over our products or reduce their inventory levels, all of which could negatively affect product demand; the risk that our investments may experience periods of significant stock price volatility causing us to recognize fair value losses on our investment; the risk posed by managing an increasingly complex supply chain that has the ability to supply a sufficient quantity of raw materials, subsystems and finished products with the required specifications and quality; the risk we may be required to record a significant charge to earnings if our goodwill or amortizable assets become impaired; risks relating to confidential information theft or misuse, including through cyber-attacks or cyber intrusion; our ability to complete development and commercialization of products under development, such as our pipeline of Wolfspeed products, improved LED chips, LED components, and LED lighting products risks related to our multi-year warranty periods for LED lighting products; risks associated with acquisitions, divestitures, joint ventures or investments generally; the rapid development of new technology and competing products that may impair demand or render our products obsolete; the potential lack of customer acceptance for our products; risks associated with ongoing litigation; and other factors discussed in our filings with the Securities and Exchange Commission (SEC), including our report on Form 10 - K for the fiscal year ended June 25, 2017, and subsequent reports filed with the SEC.

Any drop in the participation rate in this model, then, would come only from the changing sizes of the different age groups based on demographic shifts, and not any other factors.

With OpBandit, a news outlet's home page could be different for readers in one part of the country than for those in another, or could differ depending on time of day or other factors.

Every company is likely to focus on different factors when growing their business, and these objectives should be discussed in detail with both internal and external company stakeholders when creating a content strategy.

The NAV (net asset value) of a bond fund will move up or down based on a number of factors such as changes in interest rates, credit quality, and currency values (for international bonds) for the different bond holdings in the fund.

Afterwards, you may look at the individual reporting agencies, in order to fine - tune and optimize your credit score, based on the different factors each of them considers.

At this workshop, we will discuss the application of smart beta and factor investing strategies in China A-shares, how it is relevant for EM and global managers seeking access tools for portfolio completion, and how asset owners can utilize different smart beta strategies for China A allocation based on their views.

How much you pay in federal income tax depends on a few different factors like your marital status, your salary, how many allowances you claim and if you have an additional dollar withholding.

One important factor driving the geographic distribution of non-prime lending is the fixed national loan size limit on conforming loans: the limit does not account for the large variation in house prices and earning capacity across different regions.

In our statistical analysis, we include all of the confounding factors discussed above, and control for demographic and regional differences in order to tease out the effects of different factors on whether Canadians support, oppose, or have no opinion about an FTA with ChinIn our statistical analysis, we include all of the confounding factors discussed above, and control for demographic and regional differences in order to tease out the effects of different factors on whether Canadians support, oppose, or have no opinion about an FTA with Chinin order to tease out the effects of different factors on whether Canadians support, oppose, or have no opinion about an FTA with China.

Instead of the weights of different types of bonds, investors can hone in on exposure to factors that drive portfolio performance, such as interest rate risk, credit risk, and others.

Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commfactors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commfactors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commfactors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange CommFactors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.

Even decisions that as a formal matter have little to do with religion take on a different coloration when Stevens» apparent scorn for some religions is factored in.

- God, the Absolute - humanity, the human condition in its universal characteristics, - male and female, though different, equal in rights and dignity, - the cosmos, especially the planet earth available, with its limited resources, for all humanity - the planet's ecology as common essential source of life and hence of concern for all humans, present and future, - the human conscience guiding each one interiorly would be known only to each one personally, - the each group of humans has a history and a religio - cultural background of its own is a universal factor that makes for particularity and different contexts for theology, - the realization that the present increasing globalization of relationships, economy and culture impinge on theology and spirituality universally, though differently.

It may be an arrangement that factors out different aspects of the school's common life to the reign of each model of excellent schooling: the research university model may reign for faculty, for example, or for faculty in certain fields (say, church history, or biblical studies) but not in others (say, practical theology), while paideia reigns as the model for students, or only for students with a declared vocation to ordained ministry (so that other students aspiring to graduate school are free to attempt to meet standards set by the research university model); or research university values may be celebrated in relation to the school's official «academic» program, including both classroom expectations and the selection and rewarding of faculty, while the school's extracurricular life is shaped by commitments coming from the model provided by paideia so that, for example, common worship is made central to their common life and a high premium is placed on the school being a residential community.

In fact, it would likely be different for each of us, based on our knowledge of and relationship with Him, as well as our surroundings and influence and other factors.

With regard to the second, the Ethiopic text itself is a translation of a Semitic original, and a division into sources on the basis of linguistic factors would only be justified if the use of different terms corresponded to the occurrence of different conceptions, which is certainly not the case in this instance.

Different ovens (and pans) bake differently so results in baked goods will often vary depending on a variety of factors.

Speakers in this session will discuss various methods of managing separated food discards in commercial and institutional settings, sharing experiences with different approaches and tips on what factors to consider in choosing the best options.

«Every organization is at a different point in the sustainability journey so our program allows businesses to use their own baselines to determine a set of goals based on their region, operation and other factors, and then focus their resources on the practices that will make the most difference for their company, the environment and the community, continually improving year after year.»

He offered advice on all the factors a business needs to consider when buying bulk wine and how you need to factor in and understand the cycles of supply and demand in this very different world.

like I've said before, Wenger is simply stating that Sanchez is staying so that he can regain some leverage when it comes time to make a deal and to shift the focus back squarely on Sanchez... this is 101 tactics in PR management... the very fact that he even mentioned RVP's name speaks to the utterance arrogance of a man that believes he answers to no one... before you harshly judge Sanchez think carefully about what the ultimate intentions of both parties involved... Sanchez wants to win trophies and get paid generously for his efforts, whereas the club wants to pull the wool over our eyes once again so that we blame the player for wanting the very things we told him we wanted when we brought him in... how many times do we have to go down this road before we realize the only common factor in each of these scenarios is the club itself... trust me, if we showed any ambition Sanchez's contract demands would be much different... just like in other major sports players will take a «home town» discount if they see those in charge making a truly honest attempt to fight for the highest honours in their respective fields... that being said, if they see a team trying to make disparaging remarks about them in the press and not following through on their promises, they will likely try to make them pay a premium for their services or seek greener pastures... btw if anyone simply looks at the score versus Bayern today and thinks that even for a second that this was a deserved victory, just watch the game and judge for yourself... actually save yourself the anguish and just know that if it weren't for Cech and Martinez this could have been a repeat of our Champions League flopping or worse

Regardless of which ref we have, his performance depends on how many road rage incidents he encounters before the match, whether his missus had a row with him before work, whether Arsenal have provided great hospitality before and after games in the past and a lot of other different factors.

With so many different ideas on what it takes to be the top performer — scoring the most goals, creating the most assists or winning the most points — it was decided that the winner would have to be the shortlisted finalist who covers the most bases as an individual match - winner, a key player for his team - mates and one of the deciding factors in the Premier League season.

We seem to hold them in a different regard from say fingernails or hair clippings (both of which are often recycled into other products like garden fertilizer or wigs) On the other hand, there is a definite ick factor for some people.

Family Therapist Kim Bergman, PhD, shares advice on the different factors to consider in order to choose the surrogacy or donation agency for you

It's all in how that person reads / hears it, and may even be different depending on mood or any number of other factors.

Combined with data showing that a substantially higher percentage of hits to the helmets of youth players are to the side of the helmet - which the researchers attributed to a differences in the styles of play between the different age groups, as well as the fact that youth players have a tendancy to fall to the side when tackled - these factors may result in a youth player being more susceptible to impacting his head on the ground while being tackled than a high school or college player, knowledge, they said, that could aid in the design of better youth - specific football helmets.

The normal act of breastfeeding in its most basic form may not be very different between cultures, however all those other factors impact on breastfeeding outcomes.

The 27th World Health Assembly in 1974 noted the general decline in breastfeeding related to different factors including the production of manufactured breast - milk substitutes and urged Member countries to review sales promotion activities on baby foods and to introduce appropriate remedial measures, including advertisement codes and legislation where necessary.

Mother in law wanted to choose a different name for her child (husband had a row with his mother over this and used the guilt factor to getting her way) and practically had Joan follow her step by step instructions on how to care for her child.

Further in Lafrance's interview with Scott Sicherer, he goes on to say that every baby is different and many factors play into what is appropriate for each child.

No rational policy analyst could conclude that a policy is doomed to failure simply because it failed in a different context the past: this conclusion rests on a failure to interrogate the reasons for failure, and whether all relevant factors would be present in the context under consideration.

Researchers have found over the years that any number of factors — weather changes, chocolate, sleeping patterns, alcohol, stress, odors and so on — can trigger migraine headaches in different people.

Studying the two different types of twins allowed researchers to estimate the relative influence of three different factors on twins» trust and distrust trust behaviors: heritable factors — that is, genetic influences; shared environmental factors — that is, common experiences of growing up in the same family and interacting with the same immediate peers; and unshared environmental factors — or the siblings» unique experiences in life.

Acoustic guitars come in different shapes and sizes, and choosing the right one depends on a host of factors.

«Now, we know that epigenetic factors accumulate at a very different pace in each person, depending on the genetic variants of the lactase gene.»

As the researchers looked at area - level data, they note their findings may not apply to individuals living in those areas as they may have different individual - level cardiovascular risk factors, length of residence in the particular area, time activity patterns including commuting to work, and the direction in which the windows on their residence face varies.

Nintedanib, in addition to blocking vascular endothelial growth factor receptors (VEGFR) and platelet derived growth factor receptors (PDGFR), also acts on fibroblast growth factor receptors (FGFR), which makes it different to classical angiogenesis inhibitors.

There I studied the factors that limit the growth of plants on different acid soils, and in particular, the ways in which plants have adapted to hydrogen or aluminium toxicity.

The findings were independent of other risk factors such as diabetes, and are based on data from 23,376 participants which aimed to evaluate the associations between smoking, smoking cessation and tooth loss in three different age groups.

Transcription factors are responsible for either inhibiting or promoting the expression of genes, and master regulatory transcription factors are like transcription factors on steroids: their actions regulate thousands of genes in different kinds of cells.

But the extensive data from Rwanda tell a different story: An individual's willingness to take part in genocidal violence depends on many personal and social factors that influence whether and how deeply a person participates, says sociologist and Rwanda genocide researcher Hollie Nyseth Brehm of Ohio State University in Columbus.

Given their different physiology and risk factors, we have conducted the first large prospective study on the association of fruit with subtypes of stroke in Chinese adults from both rural and urban areas.»