Sentences with phrase «in ongoing phase»

In the ongoing Phase 1 study in children with SMA, all patients have completed dosing and ISIS - SMNRx was well tolerated as a single dose administered directly into the cerebral spinal fluid.

Should the slowing of clinical decline be confirmed in ongoing phase 3 clinical trials, it would provide compelling support for the amyloid hypothesis.

Intrathecal administration of an antisense drug, ISIS - SOD1Rx, has been shown to be safe and well tolerated in an ongoing Phase 1 study in patients with amyotrophic lateral sclerosis.

Based on these pre-clinical data, the HIV - 1 version of this vaccine regimen is now being evaluated in an ongoing Phase 1 / 2a international clinical study sponsored by Crucell Holland B.V., one of the Janssen Pharmaceutical Companies of Johnson & Johnson.

An HIV - 1 version of the promising vaccine regimen is now being evaluated in an ongoing Phase 1 / 2a international clinical study.

But he expects this effect to show up in another ongoing phase III trial: CARE - MS II, the preliminary results of which should be available later this year.

Not exact matches

The first phase, which is ongoing, is continuing to establish a presence in more hospitals in the U.S., Europe, and Asia.

«While we are disappointed CheckMate - 026 did not meet its primary endpoint in this broad patient population, we remain committed to improving patient outcomes through our comprehensive development program, including the ongoing Phase III CheckMate - 227 study exploring the potential of the combination of Opdivo plus [our other cancer immunotherapy] Yervoy for PD - L1 positive patients, and Opdivo plus Yervoy, or Opdivo plus chemotherapy in PD - L1 negative patients,» he added.

The company's lead product candidate, dilanubicel (NLA101), is currently being evaluated in two ongoing Phase 2 clinical trials in adult and pediatric patients with hematologic malignancies undergoing an allogeneic transplant and adult patients receiving high dose chemotherapy for Acute Myeloid Leukemia.

We can now begin to see Bultmann's New Testament work as a phase in the ongoing story.

The agitation on the Church - State issue during the late 1950's and early 1960's appeared to be but the first phase of an ongoing shift in practice in the American context.

They will tell you that safety and stabilization phase (first and ongoing) is about finding ways to stay in the present and to reduce dissociation.

Ramsey's performances this season, prior to injuring his hamstring in the first North London derby of this season, have been decent; but, given Ramsey's rise in stature and the expectations he has to live up to, as a result of his good performances in the last couple of campaigns, he wouldn't be satisfied with his displays — which included 2 goals and 1 assist — during the early phase of the ongoing season.

These changes, which will be phased in, are the result of the recommendations made by the Assembly workgroup appointed last year and charged with the examination of existing processes and ongoing efforts to improve and strengthen the Assembly rules, operations and legislative processes.

The latest phase of Project Blueprint, my ongoing research on the prospects for an overall majority, found there are as many people who voted Lib Dem in 2010 who might be persuaded to vote Tory as there are Conservatives tempted to switch to UKIP.

Frontier and Slic received funds to wire communities in Essex and Clinton counties last February as part of the second phase of the project, and installation work on those efforts is ongoing.

This phase will also address numerous ongoing and emerging water quality issues in order to help attract and support a multitude of recreation, tourism, and commercial businesses.

A phase II basket study is ongoing to determine whether these early results can be confirmed in a much larger cohort of patients.

«By looking for traces of the events in a contraction phase that may have remained in the ongoing expansion phase.

The absence of a singularity at the start of spacetime opens up the possibility that vestiges of a previous contraction phase may have withstood the phase change and may still be with us in the ongoing expansion of the Universe,» Neves said.

«Who knows, there may be remains of black holes in the ongoing expansion that date from the prior contraction phase and passed intact through the bottleneck of the bounce,» he said.

The drug has already demonstrated safety in nonhuman primate trials, and the cardiovascular research might even be able to skip ahead to a larger phase II trial based on safety data from the ongoing phase I studies, Leeper suggests.

In the interim analysis of this ongoing multiple - dose Phase 1b / 2a study, children with Type II or Type III SMA were dosed intrathecally with 3 mg, 6 mg or 9 mg of ISIS - SMNRx.

CARLSBAD, Calif., June 11, 2015 — Isis Pharmaceuticals, Inc. (NASDAQ: ISIS) today provided an update on its ongoing open - label Phase 2 clinical study of ISIS - SMNRx in infants with Type I spinal muscular atrophy (SMA).

Ongoing projects include study of exotic topological phases in the fractional quantum Hall regime, development and study of novel semiconductor / superconductor hybrid structures to host Majorana fermions, and development of devices for spin - based quantum bits (qubits).

Michael Lawler, assistant professor of physics at Binghamton, is part of an international team of physicists with an ongoing interest in the mysterious pseudogap phase, the phase situated between insulating and superconducting phases in the cuprate phase diagram.

Asterias Biotherapeutics, Inc will present new 9 - month efficacy and safety data from their ongoing Phase I / IIa trial for OPC - 1 in a workshop and poster presentation.

Prothena announced the dosing of the first Phase Ia subject on April 8, 2014; they appear to have been successful in recruiting subjects and to have quickly derived favorable safety signals, as they announced the dosing of the first PD volunteer in the Phase Ib trial on July 31, 2014, «based upon safety and tolerability observed to date in the ongoing study in healthy volunteers.»

The Phase 1/2 trial called STEP ONE, or Safety, Tolerability, and Efficacy of VC - 01 Combination Product in Type One Diabetes, is ongoing.

GS010 is currently being investigated in two additional ongoing Phase III trials, RESCUE and REFLECT, while patients in REVERSE continue to be followed for another 4 years.

Amgen has communicated with regulatory authorities and is in the process of notifying study investigators that treatment with ganitumab should be discontinued in the GAMMA trial, as well as a separate ongoing Phase 2 trial in locally advanced pancreatic cancer.

The randomized, open label Phase 2 trial is ongoing and evaluating CMB305 and atezolizumab in patients with locally advanced, relapsed, or metastatic synovial sarcoma or myxoid / round - cell liposarcoma, two types of sarcoma that tend to express NY - ESO - 1 broadly.

No expansion cohort in pancreatic cancer is being conducted, but phase II expansions are now ongoing in patients with NSCLC, SCCHN, urothelial carcinoma, melanoma, gastric or gastroesophageal junction cancer, and triple - negative breast cancer.

I have added a few carbs every now and then but always in the morning... but I want to reach 70 kilos or 65 kilod then stop from there n go on the ongoing weight loss phase of atkins

Ongoing weight loss — in this phase, you can add five more grams of carbs and nuts to your diet and keep the same rules as in the first phase.

Phase 2 — Ongoing Weight Loss (OWL) In the OWL phase of the Atkins Diet, you increase carbohydrate intake by 5grams each week to determine how many carbohydrates you can consume and still lose wePhase 2 — Ongoing Weight Loss (OWL) In the OWL phase of the Atkins Diet, you increase carbohydrate intake by 5grams each week to determine how many carbohydrates you can consume and still lose wephase of the Atkins Diet, you increase carbohydrate intake by 5grams each week to determine how many carbohydrates you can consume and still lose weight.

Ongoing - weight loss - This phase concentrates on finding the Critical Carbohydrate level for Loosing and to find out how does food group in increasing glycemic levels affect your craving control.

The release of the second Captain America movie marks the mid-point of Marvel's Phase 2, the second chapter in their ongoing series of big - screen comic book hero adventures.

The release of the second Captain America movie marks the mid-point of Marvel's Phase 2, the second chapter in their ongoing series of big - screen...

Florida's education commissioner, Eric J. Smith, issued a brief statement saying that he is «confident that with... continued support, the feedback from our first application, and the possibilities contained in ongoing legislative efforts, we will be in a very strong position to win this next phase.»

The Leaked document says «In our ongoing effort to improve our Customer Experience, we are pleased to announce the introduction of the next phase of our customer contact strategy: Click 2 Call.

Remarks: Due to their conceptual scope — and if not explicitly stated otherwise — , all models / setups / strategies do not account for slippage, fees and transaction costs, do not account for return on cash and / or interest on margin, do not use position sizing (e.g. Kelly, optimal f)-- they're always «all in «-- , do not use leverage (e.g. leveraged ETFs), do not utilize any kind of abnormal market filter (e.g. during market phases with extremely elevated volatility), do not use intraday buy / sell stops (end - of - day prices only), and models / setups / strategies are not «adaptive «(do not adjust to the ongoing changes in market conditions like bull and bear markets).

Yet, unfortunately, one of the main appeals of ETFs — that they trade «like stocks» — has also inhibited their growth, as the ticket charges of trading commissions can add up quickly for younger investors that are still in the accumulation phase and making modest ongoing contributions to a diversified multi-ETF portfolio.

Final data will be reported at ASCO Interim data for an ongoing SPA phase III in ATC within 8 months

A list of frequently asked questions (about PRA) is being updated, that will be available at the upcoming 2012 National Specialty Show and we continue to actively consider ways to address these questions in ongoing and future phases of PRA research.

In addition to that ongoing work, we now feel we're ready to embark on the final phase of our ultimate dream.

Responding to the continuing discrimination and violence faced by the LGBTI community, in 2006 Muholi embarked on an ongoing project, Faces and Phases, in which she depicts black lesbian and transgender individuals.

In a similar vein to the ongoing project Faces and Phases, Muholi creates celebratory photographs of empowered individuals who assert their identities through their confident poses, taking ownership of the spaces they inhabit.

A solo exhibition of Zanele Muholi's work is on display at the Williams College Museum of Art in Williamstown, MA, through April 27, 2014, featuring photographs from three separate bodies of work: Faces and Phases (2006 - ongoing), Beulahs (2006 - 2010), and Being (2007).

This body of work also marks a new phase in Furnas's ongoing experimentations with process and technique, as the paintings are being created in part through new robot technologies developed to his specifications.