Sentences with phrase «in optic nerve»

Glaucoma is defined as increased pressure within the eye that causes degenerative changes in the optic nerve and retina with subsequent blindness.

It bounds to the rods and cones of the eyes where it is responsible for capturing light and triggering signals in the optic nerve.

These lesions occur in the white matter of the brain and spinal cord (CNS) and in the optic nerve (CNII).

Glial changes in the optic nerve correlate with axonal degeneration in a mouse glaucoma model.

The researchers also reported that eliminating one of those genes, Rab27, led to regeneration of axons in the optic nerve or spinal cord of mice.

(2008) Age - dependent changes in morphologically identified glial cell populations in the optic nerve of the DBA / 2J mouse model of pigmentary glaucoma (Investigative Ophthalmology & Visual Science, 49: ARVO E-Abstract 3693).

In the early stages of glaucoma, there is a failure of transport of important scaffolding material, nutrients and individual fibers in the optic nerve.

Summary: Glaucoma is one of the leading causes of blindness worldwide characterized by irreversible damage in the optic nerve head (ONH).

Vision loss from glaucoma occurs when axons in the optic nerve become damaged and can no longer carry visual information to the brain.

Towards this goal, we first discovered that optic nerves regenerate physically on the surface of astrocytes which are the support cells in the optic nerve.

In this study, we will examine whether glial cells and certain proteins secreted from these cells influence axon regeneration and guidance in the optic nerve in adult mice.

They decay in the retina not just at the site of injury in the optic nerve, but back in the retina where we can be imagining them.

Roughly 2 % of people over age 35 have chronic glaucoma, in which fluid builds up inside the eyeball, leading to increased pressure and eventual death of cells in the optic nerve.

All of us daily lose some of the 2 million nerve fibers in our optic nerve and we can lose 50 - 60 percent of them without it really affecting our vision, Liu says.

Anatomical investigations have shown, however, that there are many more receptor cells in the retina than there are fibers in the optic nerve.

Not exact matches

If the human body were designed by an omniscient and omnipotent being surely it would not have made such a poor job of the laryngeal nerve in mammals, the spine not being optimal for bi-pedal gait, the blind spot caused by the optic nerve, etc. etc..

The optic nerve is working, and your baby will often turn her / his head to look in the direction of a light shining on your belly.

The master clock is located in an area of the brain just above the optic nerves and it coordinates all the body clocks so that they are in synch.

This headward fluid shift may be responsible for vision changes, flattening of the eyeball and swelling of some tissues in the back of the eye and engorgement of the optic nerve sheath seen in approximately one out of three International Space Station astronauts.

Then, the next spring, there was a sudden increase in pressure on my optic nerve and my vision suddenly dropped off.

I had an optic nerve tumor in my left eye.

To investigate these questions, Daniel Dilks and his colleagues at the Massachusetts Institute of Technology took advantage of the blind spots that occur naturally in our eyes where the optic nerve exits the retina.

And like other retinal ganglion cells in the eye, the ipRGCs grow long fibers that snake out to join the optic nerve.

Afterward, the animals» optic nerves, which connect the eyes and brain, were removed and kept alive in a dish.

In primary open angle glaucoma, pressure inside the eyeball is high because of increased fluid production, decreased excretion or both, and the optic nerve gets damaged as a result.

Doctors in those jurisdictions may prescribe cannabis to treat or manage ailments ranging from glaucoma — an eye disease in which the optic nerve is damaged — to menstrual cramps.

In experiments first reported several years ago, Blackshaw's team found a way to disrupt the normal function of the SCN without physically removing it and damaging the optic nerve.

Four had bulging of the optic nerve, three had kinks in the nerve sheath, and six had flattening of the eyeball.

«Our data clearly showed that one of the protein receptors on white blood cells called CXCR3 brings white blood cells to the optic nerve in response to production of its binding partner CXCL10 by damaged nerve tissue,» said Zhang.

When the optic nerve is injured, there are tears and swelling in the affected area that causes the nerve cells to die.

Glaucoma is characterized by rising fluid pressure in the eye that damages the optic nerve.

The electrodes stimulate the neurons in the retina, which send secondary signals down the optic nerve to the brain.

These electrodes pulse to stimulate cells in the retina, transmitting visual information along the optic nerve to the brain, creating the perception of patterns of light.

The impulse starts with excitation of the left retina, then travels down the optic nerve to cells in the midbrain and brain stem, which excite neurons near both eyes that cause the pupils to constrict.

When I was 8 years old, it caused this disorder called hydrocephalus where the tumor is blocking the cerebral fluid in the brain and that automatically creates pressure within the ventricles and it starts affecting different parts of the brain, and in my case it damaged my optic nerve.

And in transgenic pups whose optic nerves were surgically severed 4 days after birth, retinal axons grew around the gap, finding their way to the proper target areas in the brain.

We can see the optic nerve is smaller than it should be, but did it start out normally and degrade or did it never develop properly in the first place?

In the clinic, a test is conducted to see a patient's entire retina, including the optic nerve.

The discovery in a rodent model may provide insight into what happens in the visual systems of children born with a condition that prevents the optic nerve from fully developing.

Those tests don't give us the details we need to understand the nature of the pathology at the cellular level, so we modeled the disease to perform a systematic analysis of the optic nerve, from its origin in the eyes to termination in the brain.»

Importantly, the research team also looked at optic nerves of the central nervous system, which are damaged in glaucoma, and found similar protective effects from the loss of Phr1.

«In a mouse, the optic nerve looks normal at birth, which is the equivalent of the third trimester of neonatal human development,» said Fox.

We had to develop a model to examine the optic nerve at different points in time.»

Scientists at the Virginia Tech Carilion Research Institute (VTCRI) have revealed the pathology of cells and structures stricken by optic nerve hypoplasia, a leading cause of childhood blindness in developed nations.

Optic nerve hypoplasia is closely related to optic nerve atrophy, in which the optic nerve develops normally initially, but later degenerates as its cells die off.

When the UNSW approach was used to assess 13 patients with early glaucoma or optic nerve damage, and 42 people without eye disease, greater vision loss was detected in all patients than using the standard test.

A leading cause of blindness in the world especially for the elderly, glaucoma is caused by high intra-ocular pressure in the eye which then leads to damage to the optic nerve.

NERVE PROTECTORS The glowing cells in this micrograph of a mouse's optic nerve help shield electrical signals passing between eyes and bNERVE PROTECTORS The glowing cells in this micrograph of a mouse's optic nerve help shield electrical signals passing between eyes and bnerve help shield electrical signals passing between eyes and brain.

Using the patient's own scans in the simulation could greatly assist doctors performing surgery near critical parts such as the optic nerve and carotid artery, where damage could cause permanent debilitation or death.

They found that the mice can develop damage to the optic nerve despite normal pressure in the eye following KPro surgery and identified TNFa and IL - 1 as inflammatory factors involved in this process, with high levels of TNFa mediating the damage to the optic nerve.