In this multicenter Clinical Trials
in Organ Transplantation study, doctors periodically collected urine samples from 280 adult and child kidney transplant recipients for two years after transplantation.
If research progresses to a stage where its wider use would be appropriate, the Department of Health, Sackville said, would «facilitate» its
use in organ transplantation.
But that privilege appears to favor wealthier patients and may be exacerbating existing
inequities in organ transplantation, according to data presented November 9 at the American Heart Association's scientific sessions.
Strategies like the Pittsburgh Protocol that aim to minimize maintenance immunosuppression have been studied
in organ transplantation at UPMC.
A number of studies reported that HDAC inhibitors could suppress the immune response of T cells and reduce the severity of inflammation and, therefore, might be used to inhibit immune rejection or induce
tolerance in organ transplantation and BMT (20 — 23).
As a result, Hausenloy said the results suggest the procedure may still be beneficial in other medical settings of acute ischemia / reperfusion injury, such as when treating heart attack patients or
in organ transplantation.