Sentences with phrase «in other animal models»

After discussing similar effects in other animal models of cancer and a few studies showing the ability of antioxidants to prevent cancer growth, Campbell concluded that «a pattern was beginning to emerge: nutrients from animal foods increased tumor development while nutrients from plant - based foods decreased tumor development.»

This proposed role for GM1 (and indirectly GD1a) provides a rationale for its potency in suppressing diabetes in NOD mice (10) and disease onset in other animal models of autoimmunity.

Also, research in other animal models, such as rodents, has shown anesthesia exposure early in life can lead to cell death in the brain and cognitive impairments.

If the findings of the study are replicated in other animal models, such as pigs, they could have considerable implications for public health, says Oluf Pedersen, professor of genomic medicine at the Novo Nordisk Foundation Center for Basic Metabolic Research at the University of Copenhagen.

The researchers now plan to test this type of insulin in other animal models and are also working on tweaking the chemical composition of the insulin to make it even more responsive to blood - glucose levels.

They found that, within the first three days of injury, fish in the concussion group were slower to find a school of fish with which they previously swam, a measure of spatial memory which is impaired in other animal models of concussion and human patients.

They also stopped making new brain cells, something that has also been seen in other animal models of depression.

Not exact matches

Two other hooded sweatshirts in the line, one that says «Survival Expert» and one covered in an animal - shape print, were modeled by white children.

10 There is no animal model of SIDS and it has never been observed to occur naturally in any species other than humans.2 While the standardization of a SIDS diagnosis has been and continues to be elusive and / or inconsistent, it is most often applied to situations in which an otherwise healthy infant between the ages of 8 - 16 weeks, especially, but up to 12 months, dies suddenly and unexpectedly presumably during its sleep and upon postmortem examination no apparent internal causal factor (s) explaining the death can be identified.11, 12

«Gene - delivery system prevents vision loss from inherited eye disease: Initial testing in animal models holds promise for treating Leber congenital amauroisis and other congenital visual disorders.»

New research from McLean Hospital neuroscientists shows in an animal model that being bullied can have long - term, dramatic effects on sleep and other circadian rhythm - related functions, symptoms that are characteristic of clinical depression and other stress - induced mental illnesses.

«Before our work in rhesus monkeys, it has not been possible to detect or observe some of these symptoms in other HD animal models, especially emotional dysregulation,» says senior author Chan, associate professor of human genetics at Yerkes National Primate Research Center and Emory University School of Medicine.

Other projects aimed to show that animals have a theory of mind, the ability to model the thinking of others (as when we judge whether a poker player is bluffing or if a potential mate is truly in love).

She kept feeding the new data into mathematical models that factored in the animals» age, migration patterns and disease prevalence in the population, among other things.

Still, he says, other groups have arrived at opposing results regarding the role of T cells in the disease, in part, perhaps, because their animal models aren't the same.

As for the animal model, the researchers hope to now conduct experiments in monkeys or other species that more closely resemble humans.

More work is needed to determine whether the findings on rapamycin hold true in animal models of Leigh syndrome and other neurodegenerative diseases, and to ascertain how exactly rapamycin is altering the metabolism of the cells.

He sees the capability of using the team's research in the future to design models that will help game managers, conservation managers, farmers and tour operators predict animal migration, whether it's zebras or other migratory animals.

And the trouble with extrapolating so much from mouse studies is that «nobody has actually shown over the long term how long these quote un-quote improvements persist, and we don't know whether it's broadly improving aspects of aging or it's specific to certain tissues,» said Matt Kaeberlein, a biologist who studies aging in dogs and other animal models at the University of Washington.

In five other studies published over the past year, Taffe, Dickerson and their laboratories have looked at the effects of MDPV and a related «bath salts» cathinone derivative, mephedrone, in a range of animal modelIn five other studies published over the past year, Taffe, Dickerson and their laboratories have looked at the effects of MDPV and a related «bath salts» cathinone derivative, mephedrone, in a range of animal modelin a range of animal models.

«The next stage would be to repeat the study in primates, a more suitable animal model where HIV infection induces disease, in order to further demonstrate elimination of HIV - 1 DNA in latently infected T cells and other sanctuary sites for HIV - 1, including brain cells,» Dr. Khalili said.

«Mature B lymphocytes accelerate the healing of diabetic ulcers, other skin injuries: Direct application of immune cells speeds and improves healing of acute and chronic wounds in animal models.»

«This is why we are investigating in animal models how the nerve cells within the entorhinal cortex are connected with each other.»

In past studies to develop a new animal model for the brain events that support motor development, neurophysiologist Martin Garwicz of Lund University in Sweden and his colleagues discovered that the schedules by which ferrets and rats acquire various motor skills, such as crawling and walking, are strikingly similar to each other; the progress simply happens faster for ratIn past studies to develop a new animal model for the brain events that support motor development, neurophysiologist Martin Garwicz of Lund University in Sweden and his colleagues discovered that the schedules by which ferrets and rats acquire various motor skills, such as crawling and walking, are strikingly similar to each other; the progress simply happens faster for ratin Sweden and his colleagues discovered that the schedules by which ferrets and rats acquire various motor skills, such as crawling and walking, are strikingly similar to each other; the progress simply happens faster for rats.

«Usually, when researchers want a mouse or other animal model to express fluorescent proteins in certain cells, they need to develop genetically modified animals that can take months to years to make and characterize,» says former graduate student and first author Ken Chan (PhD» 17).

«I'm hopeful the techniques successfully used in this study can be applied to make animal models for other neurodegenerative diseases,» he says.

Bearden says she and her team are collaborating with other scientists to investigate brain structural differences in animal models, to find out what causes them at the cellular level.

But this remarkable therapeutic benefit isn't limited to MS. Previous research in animal models that mimic other diseases suggest that certain forms of amyloids can ease damage from strokes, traumatic brain injuries and even heart attacks.

«In less than a year, our group and others have demonstrated that multiple vaccine platforms can provide robust protection against Zika virus challenge in animal modelIn less than a year, our group and others have demonstrated that multiple vaccine platforms can provide robust protection against Zika virus challenge in animal modelin animal models.

The BUSM researchers believe the data from this study and those reported by others in animal models as well in clinical studies strongly suggest that Avodart may have serious adverse side effects that were not obvious several years ago.

In the end, three companies formed to try to exploit CRISPR to create novel medicines, while Broad and two other companies licensed the technology to partners that hoped to engineer everything from improved crops and livestock to better animal models and industrial chemicals.

The scientists said they are currently working on analyses to model the ecological role that nonhuman primates play in maintaining the diversity of astroviruses, particularly in places where they share the environment with humans and other animals.

Kohn and his former student Cecile Beguin selected four of these compounds and synthesized them along with five other analogs to evaluate in animal models at the National Institutes of Health (NIH).

The decision follows recommendations from an NIH advisory panel that said in January that the agency should curb research on chimps and instead «emphasize the development and refinement of other approaches, especially alternative animal models,» and move all but approximately 50 of the chimps to sanctuaries.

The IOM recommended that chimp research satisfy three principles: the knowledge gained would be necessary to advance the public's health; there was no other research model available to obtain that information; and that the animals would be kept in their natural habitat or in environments that closely mimic it.

The next step will be to demonstrate efficacy in larger animal models, as well as test whether this approach can be used to protect against or treat other diseases.

The engineered T cells also performed successfully in a mouse model of PV, killing desmoglein - specific B cells and preventing blistering and other manifestations of autoimmunity in the animals.

University of Adelaide researchers in Australia, supported by the Invasive Animals Co-operative Research Centre, have developed a model of the likelihood of establishment of alien species of snakes and other reptiles if they are introduced to the wild, accidentally or on purpose.

«We know from animal models that there are critical periods during early development when cells are rapidly dividing and forming the circuitry through which cells will communicate with each other to form various tissues of the body,» said Retha Newbold, a reproductive biologist at the National Institute of Environmental Health Sciences in North Carolina.

The team found that in large animal models, the capsule safely stayed in the stomach, slowly releasing the drug for up to 14 days, and potentially providing a new way to combat malaria and other infectious diseases.

In collaboration with the United States Department of Agriculture (USDA), researchers in the UPV / EHU's «Nutrition and Obesity» Group, which belongs to the Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition (CIBERobn) of the Carlos III Institute of Health, have observed in animal models that its administration reduces the build - up of body fat, which could reduce the risk of developing other diseases like diabeteIn collaboration with the United States Department of Agriculture (USDA), researchers in the UPV / EHU's «Nutrition and Obesity» Group, which belongs to the Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition (CIBERobn) of the Carlos III Institute of Health, have observed in animal models that its administration reduces the build - up of body fat, which could reduce the risk of developing other diseases like diabetein the UPV / EHU's «Nutrition and Obesity» Group, which belongs to the Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition (CIBERobn) of the Carlos III Institute of Health, have observed in animal models that its administration reduces the build - up of body fat, which could reduce the risk of developing other diseases like diabetein Physiopathology of Obesity and Nutrition (CIBERobn) of the Carlos III Institute of Health, have observed in animal models that its administration reduces the build - up of body fat, which could reduce the risk of developing other diseases like diabetein animal models that its administration reduces the build - up of body fat, which could reduce the risk of developing other diseases like diabetes.

«Alzheimer's is a condition that is hard to model in other animal species, so that was very exciting.»

The initial results of the cow study, showing that people do empathize with the animal, indicate that the same model could be useful in other experiments, he said.

«The development of this microfluidic lung model, as well as other organs - on - chip, holds the promise of improving the physiological relevance of cellular models for more accurate prediction of the effects of toxicants and drugs on humans, and for reducing the use of animals in medical and pharmaceutical research,» said Sonia Grego, Ph.D., research scientist at RTI and the project's principal investigator.

In the case of influenza, mAbs have been shown to provide prophylactic or therapeutic protection in mice and other animal models (Reuman et al., 1983; Sweet et al., 1987; Palladino et al., 1995; Renegar et al., 2004In the case of influenza, mAbs have been shown to provide prophylactic or therapeutic protection in mice and other animal models (Reuman et al., 1983; Sweet et al., 1987; Palladino et al., 1995; Renegar et al., 2004in mice and other animal models (Reuman et al., 1983; Sweet et al., 1987; Palladino et al., 1995; Renegar et al., 2004).

The researchers» strategy — generating disease - specific nerve cells, identifying a causative gene for developmental defects, validating the gene - specific defect in animal models, and then investigating interactions with other genes both in animal models and in humans — represents a promising new approach for understanding the mechanisms underlying some of the most intractable psychiatric illnesses.

PBPK modeling is used in pharmaceutical research and development and in health risk assessment to predict the absorption, distribution, metabolism and excretion of a compound in humans and other animal species.

Similar findings were present in the cerebral cortex and other regions of the brain in these animals and also found in several other mouse models of diabetes.

By tweaking an animal's DNA or using other means to inflict changes in their cells and tissues, some organisms can closely model human diseases.

When mice, fish and other animals are used in medical research, they are called models.