Sentences with phrase «in other autoimmune diseases»

Another clue is the spike in other autoimmune diseases taking place in other breeds during this time period.

In their search for such a trigger in people who had become narcoleptic, Mignot's group found elevated levels of antibodies to Streptococcus pyogenes, a bacterium that causes strep throat and has been implicated in other autoimmune diseases, such as rheumatic fever.

To extend their initial findings, the researchers seek to understand the signals that coax these cells to develop, and whether they play roles in other autoimmune diseases, such as lupus, multiple sclerosis, and type 1 diabetes.

It is possible that this type of reaction to alien substances may also be involved in other autoimmune diseases.

Not exact matches

Founded in 2011, Innovent has built a portfolio of 16 potential products for treating cancer, autoimmune disorders and other diseases, and seven of those are in clinical development.

That therapy for treating melanoma is already in the development pipeline, along with 906 other biologics targeting over 100 diseases from autoimmune disorders to viruses.

She has branched beyond desserts to other gluten - free goods in order to help those with celiac and other autoimmune diseases enjoy quality treats.

Ketones help you burn fat for energy, powerfully reduce inflammation and show promise in preventing and eradicating diabetes, cancer, autoimmune and neurodegenerative diseases like Alzheimer's and Parkinson's, and many, many other health concerns.

Dr. Song has a special interest in providing integrative care for children with complex medical issues, including autism, ADHD, asthma, autoimmune illness, eczema, failure to thrive, food allergies / sensitivities, reflux, inflammatory bowel disease and other gastrointestinal disorders, seizures and other neurologic disorders, and environmental illness.

Food allergies and intolerances join the ranks of other rapidly growing disorders in children and are often the first signs of future GI ailments and autoimmune diseases.

In one form or another, this diet keeps reappearing as a recommendation for a number of problems — autism, autoimmune disease among others.

The genetic variants associated with asthma have also effects on autoimmune diseases and other diseases with an inflammatory component such as cardiovascular diseases, cancers, neuro - psychiatric diseases, which strengthens the importance of pleiotropy in multifactorial diseases.

In addition, p.Arg90His was associated with increased risk for other autoimmune diseases, including rheumatoid arthritis and Sjögren's syndrome.

Gaining a better understanding of the underlying disease mechanisms could offer the possibility of developing new and better treatments for lupus and other autoimmune conditions in the future.

If the delivery of this technology proves successful in patients with rheumatoid arthritis, it could also be applied to other autoimmune diseases such as Type 1 diabetes.

Long noncoding RNA (lncRNA), which contains more than 200 nucleotides, are thought to play a role in autoimmune diseases and cancers by interacting with other RNA, DNA, and proteins.

Because cGVHD has a similar pathophysiology to some autoimmune diseases, it is likely that these findings will be useful for developing new treatments and preventive therapies in other conditions.

Inflammation is increasingly being implicated in heart disease, autoimmune diseases and other conditions.

«The identification of a new inflammatory target in rheumatoid arthritis holds promise for better treatment for these patients and perhaps those with other autoimmune or inflammatory diseases.»

The research fits neatly into an emerging paradigm that helps explain a recent alarming increase in food allergies and other conditions, such as obesity and autoimmune disease, and hints at strategies to reverse the trend.

Autoimmune diseases arise from an overactive immune response of the body against substances and tissues normally present in the body; in other words, the body attacks its own cells.

«The ability to control autoimmunity by autologous HSCT [hematopoietic stem cell transplantation] has been demonstrated in other treatment - refractory autoimmune conditions, including neurologic diseases.

We also observed some similarities between our findings and other emerging gut microbiota studies in multiple sclerosis; whether these indicate a «gut signature» of multiple sclerosis or of broader autoimmune disease remains to be determined,» said Professor Helen Tremlett, lead author of the European Journal of Neurology study.

A compound derived from immune cells treats psoriasis in mice and holds promise for other autoimmune diseases, according to a new study from Washington University School of Medicine in St. Louis.

The compound suppresses an inflammatory pathway that is overactive in many autoimmune diseases, suggesting that it may be effective against multiple sclerosis, rheumatoid arthritis, lupus and other autoimmune diseases as well as psoriasis.

Campylobacter jejuni infects more than a million people yearly in the United States and is also known to trigger other autoimmune disorders such as Inflammatory Bowel Disease and Reiter's arthritis.

To investigate how this might contribute to disease, immunologists Nora Sarvetnick, Cecile King, and their colleagues at the Scripps Research Institute in La Jolla, California, studied mice predisposed to type 1 diabetes and other autoimmune disorders.

These cells were not affected in patients with SLE, dermatomyositis, or other type I interferonopathies, however, suggesting that the source of interferon - can vary depending on the autoimmune disease.

Monitoring immune cell activity — including phenotyping immune cell subsets, tracking cell proliferation, and measuring cytokine production — can provide insights into the overall status of immune function in patients, particularly those undergoing immunosuppression after transplants, enduring cancer treatment, or suffering from autoimmune disease or other pathologies that affect the immune system.

17 Then again, other viral relics in our genomes may play a role in autoimmune diseases and certain cancers.

With these cells in hand, the researchers injected them into the lacrimal glands of mouse models of Sjogren's syndrome, an autoimmune disease that results in ADDE, dry mouth and other symptoms.

The research, published in PLoS One on Sept. 8, has the potential to help clinicians identify who may be at risk for developing Pemphigus vulgaris (PV), an autoimmune skin disorder, by distinguishing pathogenic (disease - causing) autoimmune antibodies from other nonpathogenic autoimmune antibodies.

It turned out that, in some people with a specific genetic variant, the vaccine, Pandemrix, caused narcolepsy and this generated a lot of discussion as to whether other autoimmune diseases may be induced by the vaccine.

Over 10,000 people in the United States receive bone marrow transplants each year for leukemia, other non-malignant blood conditions and autoimmune diseases.

There are many other known causes of inflammation, including tissue injury and autoimmune disease, although the researchers did not examine these specific conditions in this study.

«Furthermore, this strategy may be beneficial for other pathological settings in which elevated numbers of regulatory T cells are desirable, such as autoimmune diseases and solid organ transplantation,» Beilhack says.

Long noncoding RNA (lncRNA), which contains more than 200 nucleotides, is thought to play a role in autoimmune diseases and cancers by interacting with other RNA, DNA, and proteins.

It should radically transform our knowledge of immune function and dysfunction in infectious diseases, autoimmune or inflammatory disorders, and the role of immunocytes in other diseases as diverse as cancer, type 2 diabetes, and psychiatric disease.

Because it would not be feasible for a single laboratory to study each of the 50 or more genes implicated in type 1 diabetes with this approach, they decided to prioritize those genes that are also associated with other autoimmune diseases.

Timothy Springer, with colleagues Michael L. Dustin and Charles A. Dinarello, identifies and characterizes adhesion molecules, a class of cell surface proteins that function in the interactions of immune cells with other cells, including antigen - specific recognition and cell trafficking: integrin LFA - 1 involved in cytoskeleton and signaling, and intracellular adhesion molecules (ICAMs), which are binding partners (ligands) for LFA - 1 and are increased in inflammatory and autoimmune disease.

For more information regarding Bristol - Myers Squibb Clinical Trial participation, please visit www.BMSStudyConnect.com Inclusion Criteria: • Early stage IB - IIIA, operable non-small cell lung cancer, confirmed in tissue • Lung function capacity capable of tolerating the proposed lung surgery • Eastern Cooperative Oncology Group (ECOG) Performance Status of 0 - 1 • Available tissue of primary lung tumor Exclusion Criteria: • Presence of locally advanced, inoperable or metastatic disease • Participants with active, known or suspected autoimmune disease • Prior treatment with any drug that targets T cell co-stimulations pathways (such as checkpoint inhibitors) Other protocol defined inclusion / exclusion criteria could apply

It turns out that rituximab can also work for diseases such as rheumatoid arthritis, multiple sclerosis and other autoimmune conditions in which overactive B cells in the immune system contribute to the inflammation and degradation of healthy tissue.

For some people, changes in the hormone levels over time can lead to weight gain, high blood sugar, insomnia, chronic fatigue, autoimmune disease symptoms, and many other ailments.

With what we've recently come to understand in terms of the autoimmune response in type 1 diabetes, to what degree do you think this knowledge will be more generally applicable to other autoimmune diseases such as Crohn's and lupus?

Other data with either gene - deficient animals or with agonist reagents to 4 - 1BB have highlighted another aspect of biology in that a suppressive activity has been observed, for example, where stimulating 4 - 1BB in autoimmune models of MS or rheumatoid arthritis inhibits disease progression and pathology.

Patients suffering with chronic inflammatory diseases, recurrent infection, autoimmune diseases and other disorders of aging have also found promise in immune regenerative therapies.

While there are many other mouse models of lupus, said Wolin, «it is unprecedented that knocking out an intracellular RNA - binding protein would result in autoimmune disease.

This same approach is now being tested in clinical trials for people with multiple sclerosis (MS) and other autoimmune diseases in the hope that providing brand new blood cells will reset the immune system to a healthy state.

The decline of the immune system with age (immunosenescence) is reflected in the increased susceptibility to infectious diseases, poorer response to vaccination, increased prevalence of cancer, accelerated aging (frailty), autoimmune and other chronic diseases.

Doctors treat skin inflammation with topical steroids, or in more severe cases, administer immunosuppressants, similar to those used to treat other autoimmune diseases.