Sentences with phrase «in other solid tumor»

«But mounting evidence confirming angiotropism and EVMM has revolutionized the knowledge of how cancer spreads through the body to the point that other scientists have confirmed the process in other solid tumor cell types such as pancreatic cancer.»

The companies have launched a phase II trial of the antibody - drug conjugate, and are also testing it in other solid tumors, including ovarian and non — small - cell lung cancers.

Not exact matches

The focus of those hopes is the liquid biopsy: a test that could detect and analyze a solid tumor from biomarkers in the bloodstream or other easily sampled body fluids, such as saliva.

SapC - DOPS (saposin - C dioleoylphosphatidylserine), is a nanovesicle drug that has shown activity in glioblastoma, pancreatic cancer and other solid tumors in preclinical studies.

Looking to target a key pathway in order to interfere with the processes that lead to tumor spread, a research team led by Irwin H. Gelman, Ph.D., of Roswell Park Cancer Institute (RPCI) has identified a new suppressor of cancer metastasis that may point the way toward development of more effective treatments for prostate cancers and other malignant solid tumors.

«There are certainly challenges to overcome for clinical application of this kind of immunotherapy, but the newly published data are an important milestone in immunotherapy targeting solid tumors that have eluded other treatments.»

When the scientists inserted human colorectal cancer cells into zebrafish embryos and allowed them to grow for 4 days, the resulting tumors showed three hallmarks of human solid tumors: rapid cell division, formation of blood vessels to supply nutrients, and the ability to spread to other locations in the body.

Purushotham points out, «The feasibility of intraoperative CLI as shown in this study, in combination with the wide applicability of F -18-FDG across a range of solid cancers, provides a stepping stone for clinical evaluation of this technology in other solid cancer types that also experience incomplete tumor resection due to close or involved margins.»

Unlike other solid tumors, there has been limited progress in understanding the contribution of genetic risk factors to the development of uveal melanoma, researchers say, primarily due to the absence of comprehensive genetic data from patients as the large sample cohorts for this rare cancer type have not been available for research.

Although breast cancer was the initial focus and featured in the study published online today, the team has also conducted experiments with other types of solid tumors, with similar results.

Tumors in other tissues are generally more solid, which can physically impede the ability of T - cells to penetrate into the mass of the tumor.

To understand why this occurs, they examined the effect of a CDK4 / 6 inhibitor called abemaciclib in mice with breast or other solid tumors.

«The prolongation in survival seen in the prostate cancer patients participating in Dr. Sweeney's study is very impressive, dramatically longer than the typical 2 - 6 month prolongation typically observed in successful studies of other metastatic adult solid tumors,» said Bruce E. Johnson, MD, Dana - Farber's chief clinical research officer.

Our PDX models and other next - generation cancer modeling platforms allow you to address critical questions in oncology research, such as unexplained drug resistance, drug efficacy, genomic heterogeneity in solid tumor, and the role of the immune system in drug response.

Unlike other solid tumors, RCC is unique in that debulking nephrectomy has been the mainstay of therapy even in the setting of metastatic disease.

Many people suffering with cancer and diseases associated with immune dysfunction, such as lymphoma, leukemia, multiple myeloma, solid tumors, recurrent infections, neurodegenerative disorders and other chronic diseases, have turned to the Maharaj Institute in the hope of finding a more favorable prognosis and better quality of life.

Patients with hematological malignancies are at a particularly higher risk of developing severe infections when compared to other patients with solid tumors and the population in general.

The role of genetic alterations in the microenvironment of sporadic and heritable breast carcinomas and other solid tumors are being examined as they relate to clinical outcome.

Other members of Navire's scientific advisory board, comprised of leaders in cell signaling and hematological and solid tumors, include:

Cells in a tumor or tissue can change their own mechanical properties in often complex ways, using genetic programs and other feedback loops, and if jamming is to provide a solid conceptual foundation for aspects of cancer, it will need to account for this ability.

Preclinical research has encouraged us to explore the potential therapeutic benefit of Toca 511 & Toca FC in multiple other solid tumor cancers.

In addition, a growing number of immunotherapy clinical trials are in place to test this groundbreaking approach on other cancers like lymphoma, multiple myeloma, and for solid tumors, through trials in glioblastoma, mesothelioma, and ovarian and pancreatic canceIn addition, a growing number of immunotherapy clinical trials are in place to test this groundbreaking approach on other cancers like lymphoma, multiple myeloma, and for solid tumors, through trials in glioblastoma, mesothelioma, and ovarian and pancreatic cancein place to test this groundbreaking approach on other cancers like lymphoma, multiple myeloma, and for solid tumors, through trials in glioblastoma, mesothelioma, and ovarian and pancreatic cancein glioblastoma, mesothelioma, and ovarian and pancreatic cancer.

The multikinase angiogenesis inhibitor pazopanib was well tolerated and exhibited some responses in pediatric patients with soft - tissue sarcomas and other refractory solid tumors in a phase I trial.

Unlike solid tumor cancers, leukemia and other blood cancers (most lymphomas) can not be treated with surgery, and radiation is used rarely in special circumstances, such as before a transplant, Dr. Mattison says.