He is best known for his ground - breaking discovery of the HIF - 1 (hypoxia - inducible factor 1) protein, which controls genes in response to changes
in oxygen availability.
Not exact matches
The present review evaluates the evidence for such a complex system by investigating studies
in which interventions such as elevated temperature, altered
oxygen content of the air, reduced fuel
availability and misinformation about distance covered have resulted
in alterations to the pacing strategy.
If the exercise work rate is free to vary, then experimental interventions such as changes
in ambient temperature,
oxygen content of the inspired air, energy substrate
availability or the provision of incorrect distance feedback all alter the power output (pacing strategy), whereas the rate of increase
in RPE has been found to be similar between conditions.13 20 21 24 — 26
But advances
in the understanding of atmospheric
oxygen levels are challenging that idea, explains Sandra Schachat, a paleoentomologist at Stanford University, who led a recent study that modeled the gas's
availability during the hexapod gap.
Scientists say reserves can help marine ecosystems and people adapt to five key impacts of climate change: ocean acidification; sea - level rise; increased intensity of storms; shifts
in species distribution, and decreased productivity and
oxygen availability.
Dr. Simon's research is focused on how cells sense and respond to changes
in the
availability of molecular
oxygen and nutrients.
For the fetus, limitations
in nutrient and
oxygen availability cause progressive oxidative stress which prompt the release of proteins into the maternal bloodstream
in an effort to improve circulation.
His research team envisions a series of interacting processes, or feedbacks, that maintained
oxygen at very low levels principally by modulating the
availability of life - sustaining nutrients
in the ocean and thus
oxygen - producing photosynthetic activity.
While we already knew that plant roots were capable of sensing many individual soil characteristics (water, nutrients and
oxygen availability), we did not have any understanding of how they integrated these signals
in order to respond
in an appropriate way.
Known as the Antarctic Bottom Waters (AABW), these deep, cold waters play a critical role
in regulating circulation, temperature, and
availability of
oxygen and nutrients throughout the world's oceans.
As a result, the frigid flow plays a critical role
in regulating circulation, temperature, and
availability of
oxygen and nutrients throughout the world's oceans, and serves as both a barometer for climate change and a factor that can contribute to that change.
The paleoclimate data, which included mainly changes
in the
oxygen isotopes of the calcium carbonate deposits, were then compared to similar records from other caves, ice cores, and sediment records as well as model predictions for water
availability in the Middle East and west central Asia today and into the future.
Kondo, K, Sugioka T, Tsukada K, Aizawa M, Takizawa M, Shimizu K, Morimoto M, Suematsu M, and Goda N. Fenofibrate, a Peroxisome Proliferator - Activated Receptor a Agonist, Improves Hepatic Microcirculatory Patency and
Oxygen Availability in a High - Fat - Diet - Induced Fatty Liver
in Mice.
This gene is believed to signal
availability of other substances, like
oxygen, and to interact with intracellular pathways regulating growth and nutrient uptake
in other tissues of the body.
However, this study suggests that this evolutionary event is tied to the
availability of
oxygen in the atmosphere.
Deficiencies of B12, B6, folic acid and / or iron can all create a shift
in fuel
availability (specifically
in glycolysis: the oxidation or burning of sugar / glucose) which is a huge stressor on the body as it decreases
oxygen availability to every cell.
The cellular respiration process that converts your food energy into ATP is
in large part dependent on the
availability of
oxygen.
These results are consistent with the hypothesis that ketones can be used
in addition to glucose as a substrate for brain energy production even during reduced
oxygen availability.»
Oxygen availability is a vital component
in muscle function and particularly important
in aiding muscular recovery.
Joel Jameson has stated
in order to improve the aerobic energy system we need to improve the
oxygen supply,
oxygen utilisation and the substrate
availability.
These likely compromise overall blood flow and result
in hypoxia (a reduced
availability of
oxygen).
In addition to increasing the quantity of organic carbon and reducing the
availability of
oxygen, eutrophication may also affect the overall quality of organic matter for fueling CH4 - producing archaea.
Projected changes
in physical and biogeochemical drivers such as temperature, CO2 content and acidification,
oxygen levels, the
availability of nutrients, and the amount of ocean covered by ice, will affect marine life.