Sentences with phrase «in pathway analysis»

Interestingly, we also found enrichment of differentially methylated genes related to glycan metabolism in the pathway analysis in adipose tissue from unrelated patients with diabetes versus nondiabetic subjects.

By the end of 2009, I was involved heavily in pathway analysis of the array data.

He says the EEG and fMRI techniques «counter each other's weaknesses» in pathway analysis.

Further, in our pathway analyses, we find large impacts on delaying marriage in both countries.

Not exact matches

GFI reports that as their scientists investigate further, they have become more optimistic — because clean meat is so much more efficient than animal - based meat.102 One of their senior scientists, Dr. Liz Specht, has met with venture capital firms and other venture investors to present technology plans of specific clean meat companies and their pathways to commercialization.103 GFI further reports that, based partly on her analysis, many leading venture capital investors and firms have become much more interested in clean meat companies.

Only a very small number of companies have set long - term (2030 or later) targets which can be considered to be in line with a sectoral 2 °C pathway.282 An analysis of 70 of the world's largest publicly listed corporate emitters, across the aluminium, cement, chemicals and electric utilities sectors, found that 21 had targets up to 2020 which could be considered consistent with a 2 °C sectoral pathway, but only 7 had targets to 2030 or later.283 Twenty others had non-2 °C or «irrelevant» targets, and the rest had none at all.

GFI reports that as their scientists investigate further, they have become more optimistic — because clean meat is so much more efficient than animal - based meat.102 One of their senior scientists, Dr. Liz Specht, has met with venture capital firms and other venture investors to present technology plans of specific clean meat companies and their pathways to commercialization.103 GFI further reports that, based partly on her analysis, many leading venture capital investors and firms have become much more interested in clean meat companies.

Program impact pathway analysis of a social franchise model shows potential to improve infant and young child feeding practices in Vietnam

«Whatever pathway we choose to a low - carbon future, it's absolutely clear from the government's analysis that we have to go beyond oil in our transport system.

Analysis of signaling pathways that were affected pointed to changes in mitochondrial function and oxidative phosphorylation, consistent with a number of studies showing perturbations of these pathways in neurodegenerative disorders.

Scientists from the Biogerontology Research Foundation (BGRF), a UK - based charity founded to support aging research and address the challenges of a rapidly aging population, propose a new concept for signalome - wide analysis of changes in intracellular pathways, called OncoFinder, which allows for accurate and robust cross-platform analysis of gene expression data.

«Our goal is to provide objective, data - driven analysis to help inform policymakers in California and elsewhere about which technology pathway is likely to be more cost - effective in combating climate change,» Pellow said.

To unravel the complex signaling pathway map, the scientists used their own findings from the analysis of factors regulated up or down in the interplay between tissue and stem cells, linking them with the signaling pathways described in existing literature.

Show how analysis of CSF samples from Alzheimer's disease patients has identified potential new biomarkers and provided new information about some of the major pathways involved in the disease

The analyses of genetic link to BMI indicate that the central nervous system has a role in obesity susceptibility, including a pathway that responds to changes in feeding and fasting and that is thought to be targeted by an FDA - approved weight - loss drug.

«It's a step up in the transgenic technology that's available in this model system that opens up new pathways of analysis.»

Putting together their analyses of the mitochondrial DNA in each tumour cell line and the metabolic pathways at work, the team were able to deduce how each cell line's genetics directly affected its ability to multiply.

The new study, a comprehensive analysis of the genomes of 178 primary cervical cancers, found that over 70 percent of the tumors had genomic alterations in either one or both of two important cell signaling pathways.

The discovery was made during an analysis of the parasitic plant Viscum scurruloideum, a species of mistletoe whose apparent ability to survive and thrive without several genes involved in the primary energy - producing pathway of oxygen - respiring organisms could make it one of the most unusual plants on Earth.

In forensics, CUP might be used in reproducing bullet pathways, which could once again open up the Kennedy assassination conspiracy theories and revive a more accurate analysis of the strange physics of the «magic bullet.&raquIn forensics, CUP might be used in reproducing bullet pathways, which could once again open up the Kennedy assassination conspiracy theories and revive a more accurate analysis of the strange physics of the «magic bullet.&raquin reproducing bullet pathways, which could once again open up the Kennedy assassination conspiracy theories and revive a more accurate analysis of the strange physics of the «magic bullet.»

Pathway analysis also found changes in genes linked to the immune system, the body's inflammatory response, and cells» energy metabolism.

Developed by researchers in the UK and Germany and published in Nature Methods, OmniPath offers a comprehensive, unified collection of literature - curated signalling pathways based on an analysis of 41,000 scientific papers.

Former Energy Department Assistant Secretary for Policy Susan Tierney, now a principal in the Boston - based Analysis Group, said regulations underway put the United States «well on the pathway... but many of them would need to be tightened up.»

(C) Biochemical pathway impact analysis — males, The top five pathway disturbances in males were responsible for 82 % of the metabolic impact.

Evan Paull, a graduate student in Stuart's lab at UC Santa Cruz (now at Columbia University), led the computational analyses, which involved integrating the phosphoproteomic data with genomic and gene expression datasets to provide a unified view of the activated signaling pathways in late stage prostate cancer.

«Analysis of metastatic prostate cancers suggests treatment options: Study maps out abnormal signaling pathways in prostate cancer cells and provides computational approaches to identify individualized targets for therapy.»

Gene expression analysis of the animals» skeletal muscles led to another clue: differences in the kynurenine pathway of tryptophan degradation.

To study these pathways, we use a range of in vitro and in vivo approaches, including manipulating genes in mice and leveraging genome - wide analyses and chemical biology.

The ECETOC Young Scientist Award at the European Societies of Toxicology (Eurotox) Annual Congress (Rhodes, Greece, 5 - 8 October 2008) went to: Ms Nathalie Lambrecht of CARDAM VITO in Belgium for her poster, entitled «Pathway analysis of dendritic cell markers for skin sensitization.»

Used together, these technologies provide maximal statistical rigor to analyses of coregulation of genesets that are functionally related or related by involvement in a given biologic pathway.

For instance, our «activity centers» analysis requires translation from protein or gene identifiers in a pathway database to Affymetrix probe set identifiers or other gene expression array platform identifiers.

Pathway analyses implicate glial cells in schizophrenia.

Many functional categories of genes were represented in these analyses, including calcium signaling, cytokines, and growth factor pathways.

Using the liquid SIMS technique and the newly patented electrochemical System for Analysis at the Liquid Vacuum Interface (SALVI), the researchers discovered transient species and reaction pathways in the solid - liquid interface.

Birgit Kagermeier - Schenk (Weidinger, TUD)-- «Genome - wide analysis of Wnt / beta - catenin target genes in zebrafish embryogenesis and characterization of a novel modifier of Wnt signaling pathways» (2010)

Computational biologists: Download an integrated set of pathways in BioPAX format for global analysis.

PathProt is the international forum for Pathway Analysis in Proteomics.

In non-targeted analysis, the team discovered 52 metabolites related to diabetes pathology that implicated different metabolic pathways for insulin resistance and impaired pancreatic secretory function.

The Wnt and TGF - β signaling pathways were identified in the gene expression analysis as being up - regulated during the day (Fig. 4).

In multivariate analyses that included clinical factors, BRCA2 / ATM, TP53, and PI3K pathway alterations remained significantly associated with shorter time to progression.

NEWARK, Calif., May 31, 2016 (GLOBE NEWSWIRE)-- StemCells, Inc. (NASDAQ: STEM)(the «Company») today announced its decision to terminate the Company's Phase II Pathway Study in spinal cord injury following an in - depth review of data from the study and after obtaining the concurrence of the study's Interim Analysis Data Monitoring Committee (the «IA - DMC»).

Analysis of gene expression array in TSC2 - deficient AML cells reveals IRF7 as a pivotal factor in the Rheb / mTOR pathway.

Finally, our results indicate that FARO is more powerful in associating mutants in common pathways than existing methods such as co-expression analysis.

Measures including psychological measures (depressive symptoms, perceived stress, vitality and mindfulness) and detailed methods for the blood draw, processing, biomarker assays and RNA sequencing of blood samples are described in the Supplementary Appendix, along with all statistical analyses carried out for group comparisons, construction of differential expression signatures, construction of coexpression networks, construction of Bayesian networks and pathway enrichment analysis.

P.G.F. and R.G. conceived the study in coordination with K.A. M.M.A., F.R., and R.G. developed the PMI prediction models; C.P.S. and M.S. analyzed the mitochondrial transcription; A.B. the clustering modularity; A.A., M.R.H., J.C.C., C.C. and J.D. the signaling pathways; R.S. and D.D. the PSI calculation; J.C. and R.A. the signal deconvolution; A.S. contributed to the differential expression analysis; P.G.F. the remaining analysis.

Title: Proteomic analysis of the maternal protein restriction rat model for schizophrenia: Identification of translational changes in hormonal signaling pathways and glutamate neurotransmission Author: P. C. Guest et al..

To gain biological relevance of methylation differences in adipose tissue from unrelated patients with diabetes versus nondiabetic subjects, we performed a KEGG pathway analysis of the 7,046 genes that exhibit differential methylation at q < 0.15 (Supplementary Table 12) using WebGestalt.

As revealed by gene set enrichment analysis, the MAPK pathway was inactivated in the combination treatment group compared with the untreated group.

Pathway enrichment analysis of the overlapping genes of the RNA - Seq and ChIP - Seq in the combination group was then performed.

This yielded about 3,000 genes in each population; a KEGG analysis identified a total of 15 significantly enriched pathways.