He is now hoping to involve more bed - bound patients, including locked -
in patients in the study.
«That was actually the predominant problem
in patients in our study — 78 % of them had health insurance, but many of them were bankrupted anyway because there were gaps in their coverage like co-payments and deductibles and uncovered services,» says Dr. Woolhandler.
Not exact matches
While the new mid-stage
study results from DNDi were impressive (they showed cure rates of 96 % to 97 % even for the sickest
patients and those with liver scarring), more late - stage trials will be necessary before the drug is available on a large scale
in the developing world.
A new
study published
in the New England Journal of Medicine finds that Valeant Pharmaceuticals» infamous price hikes for a pair of heart drugs called nitroprusside and isoproterenol — whose prices were increased by 310 % and 720 %, respectively — had significant downstream effects on
patient care.
In all
studies, we assigned
patients measures of unconventional natural gas development activity.
We have now completed several health
studies in partnership with the Geisinger Health System, which provides primary care to over 450,000
patients in Pennsylvania, including many residing
in fracking areas.
Finally,
in our
study of symptoms, we found
patients with higher unconventional natural gas development activity had higher odds of nasal and sinus, migraine headache and fatigue symptoms compared to those with lower activity.
A series of preliminary Mayo Clinic
studies conducted
in 2010 showed promise for the potential use of a chemical component of green tea (epigallocatechin gallate)
in reducing the number of cancer cells
in patients with chronic lymphocytic leukemia.
In the asthma
study, we found increased odds among asthma
patients of asthma hospitalizations, emergency department visits and a medication used for mild asthma attacks with higher unconventional natural gas development activity, compared to those with lower activity.
In our symptom
study, we obtained questionnaires from 7,847
patients about nasal, sinus and other health symptoms.
In health care, this amounts to an hourly avalanche of new research papers, clinical trials, scientific
studies, and
patient health information.
The
study participants were asked to develop strategies for landing the rocket mentally; this,
in turn, allowed the
patients to strategize ways of blocking out hallucinatory voices inside their heads.
The
study, published today
in the journal Trauma Surgery & Acute Care Open, found most of the fictional
patients (71 %) were transferred from emergency directly to the operating theatre.
Patient experiences
in the TV drama Grey's Anatomy are, unsurprisingly, portrayed inaccurately when compared with real - life trauma cases, according to a new
study.
This
study, published
in the journal Philosophical Transactions of the Royal Society B, found that 22
patients who played the memory game made significantly fewer errors and needed significantly fewer attempts to remember the location of different patterns specific tests.
British - based GlaxoSmithKline, for example, conducts more than 100
studies a year
in Canada, with the participation of some 10,500
patients in more than 1,000 medical centres.
BIIB098: MRI and relapse results from the phase 3 EVOLVE - MS - 1
study in patients with relapsing and remitting multiple sclerosis were presented at the 70th annual meeting of the American Academy of Neurology (AAN).
In a study cited in Shawn Achor's book The Happiness Advantage, three groups of patients treated their depression with medication, exercise, or a combination of the tw
In a
study cited
in Shawn Achor's book The Happiness Advantage, three groups of patients treated their depression with medication, exercise, or a combination of the tw
in Shawn Achor's book The Happiness Advantage, three groups of
patients treated their depression with medication, exercise, or a combination of the two.
ALKS 3831: Enrollment completed for ENLIGHTEN - 2, a six - month weight
study compared to olanzapine
in patients with stable schizophrenia.
FITBIT DATA AIDS RESEARCHERS
IN UNDERSTANDING SURGERY RECOVERY: Fitbit data can help researchers and doctors predict the risk of 30 - and 60 - day readmission after surgery for cancer patients, according to a study published in the Annals of Behavioral Medicin
IN UNDERSTANDING SURGERY RECOVERY: Fitbit data can help researchers and doctors predict the risk of 30 - and 60 - day readmission after surgery for cancer
patients, according to a
study published
in the Annals of Behavioral Medicin
in the Annals of Behavioral Medicine.
The company points to a simple resource allocation problem that's hindered the most effective
patient care: the fact that it is physically impossible for oncologists to keep track of every
study, every clinical trial, and every breakthrough
in the wildly stratified world of cancer research.
A new
study using lab - engineered microtumors allowed doctors to better predict if a cancer drug treatment will work
in a
patient.
Speaking of checkpoint inhibitor drugs... Merck's star cancer immunotherapy treatment Keytruda is facing some troubling clinical trial incidents which have now compelled the Food and Drug Administration (FDA) to halt three
studies of the drug
in multiple myeloma, a rare blood cancer, after a number of
patient deaths.
To participate
in the
study, which concludes
in July 2020,
patients must be 18 years or older and have a histological - or cytological - proven diagnosis of a malignancy
in the lung, breast, head and neck, genitourinary organs or ovaries or multiple myeloma.
The first step
in the process is to surgically remove the
patient's tumor and ensure that the
patient is cancer free by confirming that there is no sign of cancer on blood tests and imaging
studies.
But Amgen's rivals
in the space, Sanofi and Regeneron (which have their own PCSK9 blocking medicine called Praluent), announced that an independent data monitoring committee hasn't seen enough significant evidence
in a huge, 18,000 -
patient cardiovascular outcomes trial to stop the
study early.
Now, the firms are hoping that the completion of the
study will show cardiovascular improvement
in these
patients, giving them a strong argument to present to reticent physicians.
Besides randomized controlled clinical trials, there are a number of ways researchers can
study how a particular cancer treatment is playing out
in the real world: there are retrospective
studies, observational
studies, and even prospective research done using
patient registries.
The
study, just published
in Science, showed that the creation of what the researchers are calling microtumors can help predict drug effectiveness
in cancer
patients better than the current standard method of testing the drugs on rodents.
Other
studies, meanwhile, are examining tryp's potential efficacy as an antifungal agent; and as a prognostic indicator
in patients with brain cancer (as seen by increased uptake of the amino acid on a PET scan).
«While we are disappointed CheckMate - 026 did not meet its primary endpoint
in this broad
patient population, we remain committed to improving
patient outcomes through our comprehensive development program, including the ongoing Phase III CheckMate - 227
study exploring the potential of the combination of Opdivo plus [our other cancer immunotherapy] Yervoy for PD - L1 positive
patients, and Opdivo plus Yervoy, or Opdivo plus chemotherapy
in PD - L1 negative
patients,» he added.
The ENDEAVOUR Phase 3
study data monitoring committee recommended dosing be suspended after it found «an imbalance of mortality»
in patients who used revusiran as compared to placebo.
«
Patients in the
study spent an average of approximately 27 minutes per day exercising over the course of an average 30 days
in recovery,» wrote the researchers.
Amgen Executive Vice President of Research and Development Sean Harper said the
study was designed to explore Kyprolis dosing regimens, noting that the the trial did not meet its goal
in improving progression - free survival versus Velcade
in patients who had not yet been treated for the disease.
«ICU care is inefficient, devoting substantial resources to
patients less likely to benefit,» their
study, published
in the February edition of JAMA Internal Medicine, concluded.
Khosla referenced a
study that asked a group of doctors to review
patient data
in order to determine whether the individual was
in need of cardiac surgery.
HEART APP IMPROVES JOHNS HOPKINS»
PATIENT OUTCOMES: A new cardiology - focused iPhone app is reducing readmission rates for heart attack
patients, resulting
in massive savings, according to a Johns Hopkins University
study.
«Among both groups,
patients taking Entresto had a 20 % or greater reduction
in cardiovascular death or heart failure hospitalization compared to those taking enalapril,» Novartis said
in a statement, citing conclusions based on analysis of data from the PARADIGM - HF
study.
The
study is
patient - funded; participants, who range
in age from late 30s through 80s, must pay $ 8,000 to take part, and live
in or travel to Monterey for treatments and follow - up assessments.
Fernando Pagan, a GUMC associate professor of neurology who directs the Movement Disorders Program at MedStar Georgetown University Hospital, said that to his knowledge, the
study «represents the first time a therapy appears to reverse — to a greater or lesser degree depending on stage of disease — cognitive and motor decline
in patients with these neurodegenerative disorders.»
The technology has proved to be quite effective
in studies — Embrace's algorithm detected 100 % of the seizures
in a multi-site clinical
study of 135
patients diagnosed with epilepsy.
When he co-founded Twine
in 2013, Moore was a researcher at MIT
studying how technology could be used to help
patients improve their health.
Amarin's clinical development program for Vascepa includes a trial known as the REDUCE - IT cardiovascular outcomes
study, an 8,175 -
patient study commenced
in 2011.
In parallel, adjudication will be completed for all MACE which occurred during the
study, including adjudication for certain events which, per protocol, can not be finally adjudicated until
patients complete their final site visit and results are available from certain non-invasive diagnostic testing conducted during such site visits.
REDUCE - IT is the first multinational cardiovascular outcomes
study evaluating the effect of prescription pure EPA therapy, or any triglyceride - lowering therapy, as an add - on to statins
in patients with high cardiovascular risk who, despite stable statin therapy, have elevated triglyceride levels (150 - 499 mg / dL).
Final
patient visits will be followed by completing data entry for the more than 35,000
patient years of
study in REDUCE - IT, and typical database quality control measures, known as cleaning.
In March 2018, patients in the study began to complete their final clinical site visits, a key step towards study completio
In March 2018,
patients in the study began to complete their final clinical site visits, a key step towards study completio
in the
study began to complete their final clinical site visits, a key step towards
study completion.
A large portion of the male and female
patients enrolled
in this outcomes
study are anticipated to also be diagnosed with type 2 diabetes.
The National Institutes for Health also brought on six health - care groups
in smaller cities to expand the
study's reach and ensure a diverse roster of
patients.
About half of the
patients in a Kymriah
study got cytokine - release syndrome, a response to the reprogrammed cells running loose
in the body.