The St. Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project has identified new mutations
in pediatric brain tumors known as high - grade gliomas (HGGs), which most often occur in the youngest patients.
Research from the Pediatric Cancer Genome Project has identified new mutations
in pediatric brain tumors known as high - grade gliomas, including tumors like diffuse intrinsic pontine glioma pictured in this MRI.
As these compounds are already approved for clinical trails
in pediatric brain tumors, these findings suggest that drugs inhibiting MEK activity could offer a new therapy option for children with these devastating tumors.
Two Emory researchers are being recognized by the Southeastern Brain Tumor Foundation (SBTF) for their work
in pediatric brain tumor research.
Not exact matches
Frustrated with the lack of investment
in research and drug development devoted to
pediatric brain tumor gliomas, the Kamens decided to take action and launch their foundation.
The Kamens claim the main thing that distinguishes their foundation from other
brain tumor foundations is their focus on
pediatric brain cancer specifically, as well as their close ties with pharmaceutical and biotech companies working
in the fields of immunotherapy and target gene therapy.
He has also authored several chapters
in scholarly texts on subjects ranging from
pediatric concussion to
brain tumors in children.
He remains a leader
in supportive care and research
in pediatric oncology, with a special focus on neuroblastoma, non-Hodgkin lymphoma, Ewing Sarcoma, acute lymphoblastic leukemia and
brain tumors.
In particular, our pediatric radiation oncologists at Floating Hospital for Children offer special expertise in the management of brain tumors, including medulloblastoma, with a combination of post-operative radiotherapy and multi-agent chemotherap
In particular, our
pediatric radiation oncologists at Floating Hospital for Children offer special expertise
in the management of brain tumors, including medulloblastoma, with a combination of post-operative radiotherapy and multi-agent chemotherap
in the management of
brain tumors, including medulloblastoma, with a combination of post-operative radiotherapy and multi-agent chemotherapy.
Engineered human immune cells can vanquish a deadly
pediatric brain tumor in a mouse model, a study from the Stanford University School of Medicine has demonstrated.
It also features prominently
in pediatric cancers such as medulloblastoma, a rare
brain tumor.
Pilocytic astrocytoma (PA) is a primarily
pediatric brain tumor caused mainly by mutations
in the BRAF gene.
«Carefully defining the molecular landscape of these
tumor subtypes may guide us
in pediatric precision medicine, to better treat children with
brain tumors,» said Payal Jain, PhD, a postdoctoral researcher at Children's Hospital of Philadelphia (CHOP).
«Biology of childhood
brain tumor subtypes offers clues to precision treatments: Researchers reveal differences among gene fusions
in low - grade
pediatric brain tumors.»
Sanford Research scientists are published
in Nature Cell Biology for their work developing a model to explore therapies for a
pediatric brain tumor known as choroid plexus carcinoma.
Researchers investigating
pediatric low - grade gliomas (PLGG), the most common type of
brain tumor in children, have discovered key biological differences
in how mutated genes combine with other genes to drive this childhood cancer.
Medulloblastoma is diagnosed
in about 400 children and adolescents annually
in the U.S., making it the nation's most common
pediatric brain tumor.
Medulloblastoma occurs
in infants, children and adults, but it is the most common malignant
pediatric brain tumor.
Medulloblastoma is diagnosed
in about 400 children annually
in the U.S., making it the most common
pediatric brain tumor.
In a previous study, Sredni and colleagues were the first to describe PLK4 as a therapeutic target for brain tumors and in pediatric cance
In a previous study, Sredni and colleagues were the first to describe PLK4 as a therapeutic target for
brain tumors and
in pediatric cance
in pediatric cancer.
Previously, the authors of the study have shown that an experimental drug that inhibits polo - like kinase 4 (PLK4) stopped
pediatric brain tumor growth
in vitro.
«This is exciting because it's the first animal model of
pediatric high - grade gliomas, or malignant
brain tumors,» says Maria Castro, Ph.D., senior author of the paper and a professor
in the departments of Neurosurgery and Cell and Developmental Biology at U-M.
A new PNAS paper from geneticist Tamara Caspary's lab identifies a possible drug target
in medulloblastoma, the most common
pediatric brain tumor.
UT Southwestern Medical Center's
pediatric brain tumor team has dedicated subspecialists, state - of - the - art radiation technology, and access to advanced
pediatric treatments that other hospitals
in North Texas don't offer.
UT Southwestern's
pediatric neurosurgeons are some of the most gifted neurosurgeons
in the country and have, along with their colleagues
in neuro - oncology, radiation oncology, and neuro - radiology, dedicated their lives to the care of children with
brain tumors.
We treat 80 to 100 children with
brain tumors each year, and we established the first
pediatric neuro - oncology program
in Texas.
The University of Michigan is a national leader
in basic, translational, and clinical research on
pediatric brain tumors.
In this conference, members of the U-M
pediatric brain tumor team and physicians from leading national
brain tumor institutions incorporate molecular results from
pediatric brain tumors (Mi - Oncoseq and molecular pathology) into targeted treatments for patients.
C.S. Mott Children's Hospital has expertise
in treating the full range of
pediatric brain tumor types, including:
U-M is emerging as a leader
in the care for and research into better treatments for
pediatric brain tumors.
He continues to study cancer gene function
in his Georgetown lab, and has recently identified a new cancer gene called STAG2 that is among the most commonly mutated genes
in cancer, involved
in causing bladder cancer,
pediatric bone
tumors, leukemias,
brain tumors, and other
tumor types.
Our groundbreaking
Pediatric Mi - Oncoseq Program is an internationally known precision oncology program focusing on the genetic analysis of
pediatric cancer patients including
in children with malignant
brain tumors, and determines whether targeted treatments may be available based upon their personalized
tumor genomic sequencing profiles.