«Small molecule inhibitor shows promise
in precision cancer targeting.»
Not exact matches
Yet, while Shelley Hwang, chief of breast surgery at Duke
Cancer Institute and vice chair of research at Duke University's Department of Surgery, agrees
in principle, she also has concerns about all the new diagnostic potential that will come with
precision medicine.
He cites the progress the medical community has made
in treating
cancer through immunotherapy, and he's a big believer
in the potential
in precision health.
IBM (ibm) Watson is teaming up with Quest Diagnostics (dgx)
in a significant expansion of its ongoing
cancer genomic sequencing and
precision medicine push.
The Harvard Business School Kraft
Precision Medicine Accelerator is working with the MMRF and other
cancer partners to harness the potential of master protocols
in precision oncology.
Additionally, the agency would continue efforts to advance
precision medicine and
cancer genomics
in support of the Million Veteran Program (MVP), which aims to collect blood samples and health information from one million veteran volunteers to study how genes affect health.
«Such advances
in sequencing technology facilitate rational
precision therapies for individuals with late - stage
cancer.»
In 2004 the
precision strategy got a boost with two FDA approvals for pharmaceuticals to treat colon
cancer — the second most common cause of U.S.
cancer deaths.
Little progress has been made
in outcomes for pancreatic
cancer patients over the last 40 years, and we believe that
PRECISION Panc will reshape how we approach treatment development.
«New era
in precision medicine for pancreatic
cancer.»
«It represents a model of collaboration between
cancer centers, represents a monumental operational, technical and computational achievement and finally represents the value of
precision medicine
in finding actionable mutations.»
«We're
in an era of cutting - edge
precision medicine, yet we can still achieve meaningful progress with conventional treatments,» said Gregory A. Masters, MD, FACP, FASCO, Chair of ASCO's
Cancer Communications Committee.
«To realize the benefits of the most recent progress
in cancer genomics, clinical implementation of
precision medicine approaches is needed
in the form of novel biomarker assays.
Study co-leader Wyndham Wilson, M.D., Ph.D., NCI Center for
Cancer Research, added, «This is the first clinical study to demonstrate the importance of
precision medicine
in lymphomas.»
«New three -
in - one blood test opens door to
precision medicine for prostate
cancer: Test picks out men for treatment, detects early signs of resistance and monitors
cancer's evolution over time.»
«However, there is still much more to understand before the potentially huge benefits of widespread
precision treatment for prostate
cancer will reach men
in clinics across the UK.
Scientists have developed a three -
in - one blood test that could transform treatment of advanced prostate
cancer through use of
precision drugs designed to target mutations
in the BRCA genes.
Dr Fiona Blackhall, a senior lecturer
in The University of Manchester's Institute of Cancer Sciences and a consultant based at The Christie NHS Foundation Trust — both part of the Manchester Cancer Research Centre — said: «In order to introduce precision medicine, where each cancer patient receives treatment designed to target the genetic makeup of their individual cancer, we need to compare how effective the new targeted treatment is compared to standard chemotherapy treatment.&raqu
in The University of Manchester's Institute of
Cancer Sciences and a consultant based at The Christie NHS Foundation Trust — both part of the Manchester Cancer Research Centre — said: «In order to introduce precision medicine, where each cancer patient receives treatment designed to target the genetic makeup of their individual cancer, we need to compare how effective the new targeted treatment is compared to standard chemotherapy treatment.&
Cancer Sciences and a consultant based at The Christie NHS Foundation Trust — both part of the Manchester
Cancer Research Centre — said: «In order to introduce precision medicine, where each cancer patient receives treatment designed to target the genetic makeup of their individual cancer, we need to compare how effective the new targeted treatment is compared to standard chemotherapy treatment.&
Cancer Research Centre — said: «
In order to introduce precision medicine, where each cancer patient receives treatment designed to target the genetic makeup of their individual cancer, we need to compare how effective the new targeted treatment is compared to standard chemotherapy treatment.&raqu
In order to introduce
precision medicine, where each
cancer patient receives treatment designed to target the genetic makeup of their individual cancer, we need to compare how effective the new targeted treatment is compared to standard chemotherapy treatment.&
cancer patient receives treatment designed to target the genetic makeup of their individual
cancer, we need to compare how effective the new targeted treatment is compared to standard chemotherapy treatment.&
cancer, we need to compare how effective the new targeted treatment is compared to standard chemotherapy treatment.»
In the era of
precision medicine, targeting the mutations driving
cancer growth, rather than the tumor site itself, continues to be a successful approach for some patients.
«We have found another piece
in the
cancer puzzle — knowledge that could one day be used for more
precision in screening and breast
cancer prevention, and also help with therapeutic approaches to block some of the earliest alterations before
cancer develops and starts to spread.»
If these results are validated
in subsequent testing,
in the future an oncologist will have many more options for
precision cancer therapy.»
At the German
Cancer Research Center, (Deutsches Krebsforschungszentrum, or DKFZ)
in Heidelberg, scientists working
in precision oncology are also taking full advantage of advances
in genomic technology.
«Pathologists who specialize
in molecular diagnostics and lung
cancer collaborated to create the guideline to minimize variation and provide greater
precision in the care of patients.»
In an era of
precision medicine, the guideline provides recommendations for pathologists, oncologists, and other
cancer health professionals on the current state - of - the - art recommendations for the molecular testing of lung
cancer.
«Having these personalized laboratory models, which we can make
in a matter of weeks, will let us test multiple different drugs on the tumor and help us bring
precision medicine to individuals with bladder
cancer.»
«The study represents a clear breakthrough
in precision medicine, as this molecule only kills the
cancer cells that express the
cancer - causing gene — not healthy cells.
A team of researchers at the Massachusetts General Hospital and Harvard Medical School
in Boston has developed technologies for
precision measurement of cell migration speed before and applied the new tool to study the variations of migration speed
in population of
cancer cells.
The findings are being presented as part of a poster presentation by members of the Rutgers
Cancer Institute
precision medicine team at the Annual Meeting of the American Association for
Cancer Research (AACR) which begins this weekend
in New Orleans.
Other biomarkers and genetic signatures are being used
in an effort to predict the aggressiveness of an individual patient's prostate
cancer, «but the current information doesn't make it possible for their gene signature to be an actual target for
precision medicine targeted therapy,» Ellis explained.
Identification and functional validation of proteins involved
in tumorigenesis are essential steps toward advancing
cancer precision medicine.
Researchers leading the largest genomic tumor profiling effort of its kind say such studies are technically feasible
in a broad population of adult and pediatric patients with many different types of
cancer, and that some patients can benefit by receiving
precision drugs targeted to their tumors» mutations or being enrolled
in clinical trials.
The authors concluded that «Genomic results may alter management
in diverse scenarios; however, additional barriers must be overcome to enable
precision cancer medicine on a large scale.»
«
In identifying a specific abnormality in a patient's cancer instead of the overall organ where it first presented, the opportunity exists to provide tailored therapies for patients,» notes Lorna Rodriguez, MD, PhD, director of the precision medicine initiative at the Cancer Institute and professor of obstetrics, gynecology and reproductive sciences at Robert Wood Johnson Medical Schoo
In identifying a specific abnormality
in a patient's cancer instead of the overall organ where it first presented, the opportunity exists to provide tailored therapies for patients,» notes Lorna Rodriguez, MD, PhD, director of the precision medicine initiative at the Cancer Institute and professor of obstetrics, gynecology and reproductive sciences at Robert Wood Johnson Medical Schoo
in a patient's
cancer instead of the overall organ where it first presented, the opportunity exists to provide tailored therapies for patients,» notes Lorna Rodriguez, MD, PhD, director of the precision medicine initiative at the Cancer Institute and professor of obstetrics, gynecology and reproductive sciences at Robert Wood Johnson Medical S
cancer instead of the overall organ where it first presented, the opportunity exists to provide tailored therapies for patients,» notes Lorna Rodriguez, MD, PhD, director of the
precision medicine initiative at the
Cancer Institute and professor of obstetrics, gynecology and reproductive sciences at Robert Wood Johnson Medical S
Cancer Institute and professor of obstetrics, gynecology and reproductive sciences at Robert Wood Johnson Medical School.
As part of the
precision medicine initiative at the
Cancer Institute of New Jersey, investigators — which include colleagues from Rutgers Robert Wood Johnson Medical School and RUCDR Infinite Biologics, the world's largest university - based biorepository, located within the Human Genetics Institute of New Jersey — wanted to define the relationship of ERBB2 alterations
in the pleomorphic form of the disease.
Recognizing a need to further explore genomic profiling
in pediatric malignancies, the Hugs for Brady Foundation has committed $ 300,000 to the
precision medicine initiative at Rutgers
Cancer Institute of New Jersey.
They included efforts to prepare communities to adapt to climate change; the
cancer moonshot,
precision medicine, and brain research
in the health arena; a network of advanced manufacturing institutes to recapture global industrial dominance; and public - private partnerships to improve science and math education.
«Clinical and research leaders
in cancer genomics are making tremendous progress towards bringing
precision medicine to
cancer patients, but genomic data interpretation is a significant obstacle, and that's where Watson can help.»
A. Right now, The
Cancer Institute of New Jersey and other institutions are engaged in an approach known as precision / personalized medicine, where systems biologists and other specialists collaborate with scientists and clinicians to identify the molecular alterations associated with cancer, and then tailor regimens of targeted agents to those specific alterations or muta
Cancer Institute of New Jersey and other institutions are engaged
in an approach known as
precision / personalized medicine, where systems biologists and other specialists collaborate with scientists and clinicians to identify the molecular alterations associated with
cancer, and then tailor regimens of targeted agents to those specific alterations or muta
cancer, and then tailor regimens of targeted agents to those specific alterations or mutations.
The overall
precision medicine initiative at the
Cancer Institute is supported
in part by a $ 10 million anonymous gift.
Agios has leveraged its core capabilities
in cellular metabolism and
precision medicine to build a product engine that is focused
in the therapeutic areas of
cancer and rare genetic diseases.
«This is a very exciting advance
in our understanding of
cancer, and perhaps a first step toward a personalized,
precision approach to the treatment of glioblastoma,» said Stephen G. Emerson, MD, PhD, director of the HICCC and the Clyde ’56 and Helen Wu Professorship
in Immunology at the Columbia University College of Physicians and Surgeons.
In my laboratory at NYU Langone, I focus on
precision medicine, rare tumors, and early detection and prevention of gynecologic
cancers.
Dr. Mody is leading a clinical trial investigating the role of next generation sequencing (NGS)
in precision oncology for developing novel biomarkers and therapeutic targets against refractory childhood
cancers.
In effect, Affigen uses
cancer's «Achille's Heel»: the proteins which distinguish tumor cells from normal cells, that can target tumor cells for destruction with extreme sensitivity and
precision.
His research interests include new drug development against childhood
cancers and role of
precision medicine
in pediatric oncology.
NCI has launched a series of
precision medicine clinical trials since 2014, many genetically targeted therapies are currently available to
cancer patients, and many more are expected to become available
in the near future.
On Dec. 1 - 2, those issues will come to the fore as national experts
in genetics, medicine, law, big data and other fields gather for Frontiers
in Precision Medicine II:
Cancer, Big Data and the Public, a unique
precision medicine symposium at the University of Utah S.J. Quinney College of Law, Center for Law and Biomedical Sciences, University of Utah Health Sciences, Huntsman
Cancer Institute, and University of Utah Center for Excellence
in ELSI Research (UCEER) addresses those topics as
precision medicine is gaining more attention nationwide from health care systems, practitioners, researchers, insurers and federal agencies.
What was once dismissed as futuristic has now become reality for some
cancer patients, and with leading - edge research and groundbreaking partnerships, City of Hope stands
in the
precision medicine vanguard.
Vice President Joe Biden's «
Cancer Moonshot» initiative is an example of
precision medicine
in its goal of using big data and
precision oncology techniques.
For almost three decades, Dr. Maharaj has been treating patients with blood
cancers and immune disorders
in a totally outpatient basis, leading the field for a personalized and
precision - based approach to disease.