They discovered that patients who had microscopic metastatic disease
in their regional lymph nodes and a tumor that had a breakdown of the overlaying skin responded best to ipilimumab treatment.
The prognosis for patients with metastatic melanoma remains poor, with 5 - year survival rates of 63 percent in patients who have metastatic disease
in regional lymph nodes, and only 17 percent in patients who have metastatic disease in distant sites.
Not exact matches
For each of these cancer sites, the researchers calculated important
regional and county differences
in advanced stage of diagnosis, which takes into account the growth and size of the tumor and whether it has spread to the
lymph nodes or other organs.
Radiotherapy to the chest wall and
regional lymph nodes (under the arm, above the collar bone and under the breast bone), known as
regional nodal irradiation, is used after mastectomy
in women with
node - positive breast cancer who are treated with adjuvant systemic therapy.
The degree of involvement of
regional lymph nodes is predictive of overall survival and is also a key factor
in determining the appropriateness of adjuvant therapy and the patient's eligibility for investigational trials.
In the case of high risk features such as
regional lymph node involvement, then adjuvant interferon alpha may be considered [53].
The authors found that somatic mutations of TP53 (often referred to as the master molecule)
in the stroma correlate with
regional lymph node metastases (spread of cancer to the
lymph glands).
Instead, immune responses are induced
in the local and
regional lymph nodes (ie, the tonsils, adenoids, and cervical
lymph nodes).
Spread of mammary carcinomas
in both dogs and cats is primarily to
regional lymph nodes and lungs.
AGA can go to any tissue
in the body, but tends to spread first to the
regional lymph nodes (primarily sublumbar
nodes).
Ultrasonorgraphy is important
in viewing the
regional lymph nodes and metastases
in other abdominal organs.
Lymphoma is categorized into five stages, depending on the extent of the disease
in the body: single
lymph node enlargement (stage I),
regional lymph node enlargement (stage II), generalized
lymph node enlargement (stage III), liver and / or spleen involvement (stage IV), and bone marrow and blood involvement (stage V).