Sentences with phrase «in regulating gene expression»

Both were known to be active in regulating gene expression in the liver, kidney, and intestine.
The results of this study contrast sharply with the generally accepted view of the key roles that these epigenetic marks play in regulating gene expression.
MicroRNAs are short noncoding RNAs that play critical roles in regulating gene expression in normal physiology and disease.
This RNA does not code for a protein but is highly conserved by evolution, occurring in many species, and is involved in regulating gene expression during human development and cancer.
Enzymes that chemically modify DNA, known as DNA methyltranferases, play critical roles in regulating gene expression during development, but their role in cancer formation is less clear.
In the past decade or so, researchers have also come to appreciate the key roles played by chromatin proteins and RNA in regulating gene expression.
The study also raises questions about the role of histone acetylation in regulating gene expression.
Now researchers from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg show robust evidence that not only the inherited DNA itself but also the inherited epigenetic instructions contribute in regulating gene expression in the offspring.
Small non-coding RNAs, including microRNAs, are known to be important players in regulating gene expression in many contexts, including tissue development.
MicroRNAs or miRNAs are short non-coding RNA sequences that can participate in regulating gene expression, through post transcriptional silencing of mRNAs.
While the role that DNA - binding proteins play in regulating gene expression at the transcriptional level is well studied, how RNA - binding proteins control gene expression at the post-transcriptional level is less clear.
A microRNA — a small piece of RNA involved in regulating gene expression — functions as an oncogene to drive the development of lung...
MicroRNAs (miRNAs) are small non-coding RNA molecules that play a crucial role in regulating gene expression in animals and plants.
The team's work provides one of the first quantitative global analyses of the role RNA - binding proteins play in regulating gene expression and makes a significant contribution to knowledge of this regulatory process.
Beachy continues research on virus resistance for crops for developing countries, as well as fundamental research in cell and molecular mechanisms in plant virology, and in regulating gene expression in plants.
«MicroRNAs, or miRNAs, are short RNA molecules that play a prominent role in regulating gene expression.
DNA is wrapped around proteins called histones, which serve to package the DNA inside the cell nucleus and play an important role in regulating gene expression.
In the first study to run a genome - wide analysis of Short Tandem Repeats (STRs) in gene expression, a large team of computational geneticists led by investigators from Columbia Engineering and the New York Genome Center have shown that STRs, thought to be just neutral, or «junk,» actually play an important role in regulating gene expression.
More recently, some small RNAs have been found to be involved in regulating gene expression.
Single - stranded, noncoding micro-ribonucleic acids (microRNAs), consisting of 18 - 23 nucleotides, play a key role in regulating gene expression.
The second group, headed by John Mattick, a molecular biologist at University of Queensland, St. Lucia, in Australia, identified a new class of short RNAs that also seem to be involved in regulating gene expression, though their function needs to be confirmed.
Deciphering the processes involved in regulating gene expression is not only essential for understanding normal development, but also for comprehension of the molecular changes that occur in inborn errors of embryonic development as well as in somatic mutations that lead to cancer.
Both mRNA and small RNAs play important roles in regulating gene expression, Dr. Zhang explained.
Other types of RNA play important roles in regulating gene expression (microRNAs), RNA processing by the spliceosome (small nuclear RNAs or snRNA), and protein translation (tRNAs).
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