Sentences with phrase «in response to glucose»

What if a person secretes too much insulin in response to a glucose load?

Our results showing a reduction in hypothalamic CBF in response to glucose ingestion are consistent with prior fMRI studies in healthy volunteers, which observed a decrease in hypothalamic activity in response to ingestion of glucose13 - 15,22 or a liquid meal, 23 a finding posited to reflect a central biomarker of satiety.

Never went up in response to glucose but went down every hour till it hit 52 by the 3 hour.

Effects of oral L - carnitine supplementation on insulin sensitivity indices in response to glucose feeding in lean and overweight / obese males.

Neurons seem to be the most sensitive cells to high glucose levels, and the severity of neuropathy in diabetes is correlated with how high blood glucose rises above 140 mg / dl in response to a glucose tolerance test.

Maybe one secretes a little more insulin in response to the glucose, or is a little more sensitive or resistant to the insulin secreted.

Secondary messengers acts to repair the doorbell so that the cell doors open in response to glucose, resulting in less insulin needing to be secreted.

As a result, the increased acetate stimulated the beta cells of the pancreas to secrete more insulin in response to glucose.

Type 2 diabetes patients, who represent the 85 % of people with diabetes, have fewer beta cells and less ability to secrete insulin in response to glucose.

Healthy beta cells produce and release insulin in response to glucose in the blood, and they are vital to treating and preventing diabetes.

The cells (blue), made from stem cells, can secrete insulin (green) in response to glucose.

In the glucose tolerance tests, F0, F1, and F2 IVC males but not females had a lower ability to rectify blood glucose concentrations in response to glucose administration (Fig. 4C).

Novocell also demonstrated earlier this year, that hES - derived pancreatic progenitorsdevelop into human islet cells capable of producing insulin in response to glucose and ameliorating diabetes in animal models.

The researchers found cerebral fructose levels rose significantly in response to a glucose infusion, with minimal changes in fructose levels in the blood.

These receptors determine the differentiation of cell function and may increase the ability to produce insulin in response to glucose by beta cells.

From the first day of transplantation, the cells produced insulin in response to glucose spikes in the mice's blood, alleviating the modeled diabetes.

When human stem cells develop into beta cells in a dish, they only reach a precursor stage, unable to fully mature; this prevents them from effectively producing insulin in response to glucose.

«This gives the diabetic a way to make insulin in response to glucose and potentially would obviate (or at least reduce) the need for insulin injection,» March explained in an email.

Not exact matches

The Glycemic Index ranks carbohydrates according to their impact on the body's blood sugar level (glycemic response — conversion to glucose in the body).

Such a rapid response, he says, «could be very important for hypoglycemic [low glucose level] episodes in children, which can cause children to go into shock.»

As a result, Schultz believes his technology «will be able to rapidly reflect the dynamic changes in tissue glucose with a response time of about three to five minutes.»

«That observation is in line with the usual response of cells to oxygen deprivation: they save on the consumption of oxygen by converting glucose to lactate instead of burning the glucose.

Most importantly, these cells protected mice from developing diabetes in a model of disease, having the critical ability to produce insulin in response to changes in glucose levels.

Cells in the pancreatic islets called beta cells are responsible for modulating the body's response to the rise and fall of blood glucose levels after a meal.

Studies in rodents and in human fetal beta cells have showed that the responses of very young beta cells to increases in blood glucose are blunted when compared to their more - mature counterparts.

The reason for the reduced glucose levels associated with bacterial meningitis was believed to be the need for glucose as fuel by infiltrating immune cells in response to infection.

Insulin is secreted in response to a type of carbohydrate called glucose.

When the researchers raised mice that lacked ERRγ, the animals» beta cells couldn't produce insulin in response to blood glucose spikes.

Segal and his colleagues found that one person's blood glucose might spike in response to a particular food, while that same food would actually lower another person's.

The adaptation makes sense: reducing enzyme activity keeps more free cortisol in the body, which allows the liver and kidneys to maximize stores of glucose and metabolic fuels — an optimal response to prolonged starvation and other threats.

Additionally, a lower glycemic response equates to a lower insulin demand, better long - term blood glucose control and a reduction in blood lipids.

Using a small saliva, urine, or blood sample, equivalent to the amount required by blood glucose monitors to test blood sugar levels, the sample is applied to the sensors, triggering a response that provides visually evident results in as little as an hour.

The 2000 and 2010 studies led by Stuart A. Chalew, MD, Professor of Pediatrics and Head of the Division of Endocrinology in the Department of Pediatrics at LSU Health New Orleans School of Medicine, first reported the major difference in the hemoglobin A1c (HbA1c) response to blood glucose between African - American and Caucasian children with diabetes.

The animals were subsequently able to produce the insulin analogue in response to changes in their blood - glucose levels throughout the eight month study period.

Researchers at North Carolina State University and the University of North Carolina at Chapel Hill may have developed a rudimentary artificial pancreas capable of releasing insulin in response to real - time changes in blood glucose content.

In their study Loeken and her group, including Yichao Wu, Marta Viana, and Shoba Thirumangalathu, used mice and cell lines to test their hypothesis that AMPK might be stimulated in the embryo and that stimulation of AMPK was responsible for blocking Pax3 expression and causing neural tube defects in response to high glucosIn their study Loeken and her group, including Yichao Wu, Marta Viana, and Shoba Thirumangalathu, used mice and cell lines to test their hypothesis that AMPK might be stimulated in the embryo and that stimulation of AMPK was responsible for blocking Pax3 expression and causing neural tube defects in response to high glucosin the embryo and that stimulation of AMPK was responsible for blocking Pax3 expression and causing neural tube defects in response to high glucosin response to high glucose.

In particular, glucose utilization and related unfolded protein response as well as autophagy were reported to become deranged in diverse cancer cells [8, 72, 73In particular, glucose utilization and related unfolded protein response as well as autophagy were reported to become deranged in diverse cancer cells [8, 72, 73in diverse cancer cells [8, 72, 73].

Currently, she is using imaging techniques to explore the effects of glucose on brain responses to food cues in children who are at - risk for developing obesity and / or diabetes later in life.

While most rodents tend to become obese on high - fat diets, there can be variable responses in weight gain, glucose tolerance, insulin resistance, triglycerides and other parameters depending on the strain.

Defective lipid delivery modulates glucose tolerance and metabolic response to diet in apolipoprotein E-deficient mice.

Defective Lipid Delivery Modulates Glucose Tolerance and Metabolic Response to Diet in Apolipoprotein E — Deficient Mice.

Furthermore, transcription of CCHa2 is altered in response to nutritional levels, particularly of glucose.

For example, mammalian insulin is secreted from pancreatic β - cells in response to high blood glucose levels; insulin is then received by its receptor in the liver as well as in many other tissues to promote glucose uptake and anabolism, thereby reducing blood sugar levels [1].

Among their work, the investigators are looking at how ROS affects gene regulatory responses in cells that are exposed to elevated glucose levels or other stimuli.

For example, blood glucose levels provide an indication of disease control in diabetes and a rapid measure of a patient response to a diabetes drug.

The elevated insulin concentrations produced by the IVC males may represent a compensatory response to maintain glucose levels, as is frequently observed in insulin - resistant diabetes type 2 in humans and animals [33].

Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism.

Response to both insulin and glucose dosing was normal in Lyplal1 (tm1a (KOMP) Wtsi) homozygous mice, with normal fasting blood glucose concentrations.

When Dunstan had office workers interrupt their sitting with regular activity breaks, they experienced a 30 per cent improvement in their body's response and sensitivity to a meal containing glucose — which means the movement was helping to reduce risks of diabetes type 2.

Heilbronn LK, Civitarese AE, Bogacka I, Smith SR, Hulver M, Ravussin E. Glucose tolerance and skeletal muscle gene expression in response to alternate day fasting.